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Tytuł:
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Hybrid mesoporous nanostructured scaffolds as dielectric biosimilar restorative materials.
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Autorzy:
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Rivas-Mundiña B; Surgical and Medical-Surgical Specialities Department, Universidade de Santiago de Compostela, Spain.
Vargas-Osorio Z; Department of Applied Physics, Nanotechnology and Magnetism Laboratory (NANOMAG), Universidade de Santiago de Compostela, Santiago de Compostela, Spain.
Yáñez-Vilar S; Department of Applied Physics, Nanotechnology and Magnetism Laboratory (NANOMAG), Universidade de Santiago de Compostela, Santiago de Compostela, Spain.
Rizk M; Department for Preventive Dentistry, Periodontology and Cardiology, University Medical Center Göttingen, Göttingen, Germany.
Piñeiro Y; Department of Applied Physics, Nanotechnology and Magnetism Laboratory (NANOMAG), Universidade de Santiago de Compostela, Santiago de Compostela, Spain.
Pérez-Sayáns M; Surgical and Medical-Surgical Specialities Department, Universidade de Santiago de Compostela, Spain.; Instituto de Investigación de Santiago de Compostela (IDIS), Santiago de Compostela, Spain.
Rivas J; Department of Applied Physics, Nanotechnology and Magnetism Laboratory (NANOMAG), Universidade de Santiago de Compostela, Santiago de Compostela, Spain.
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Źródło:
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Bio-medical materials and engineering [Biomed Mater Eng] 2021; Vol. 32 (4), pp. 243-255.
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Typ publikacji:
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Journal Article
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Język:
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English
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Imprint Name(s):
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Publication: Amsterdam : IOS Press
Original Publication: New York : Pergamon Press, c1991-
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MeSH Terms:
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Biosimilar Pharmaceuticals*
Nanostructures*
Porosity ; Silicon Dioxide
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Contributed Indexing:
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Keywords: Mesoporous scaffolds; dielectric properties; restorative materials; textural properties
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Substance Nomenclature:
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0 (Biosimilar Pharmaceuticals)
7631-86-9 (Silicon Dioxide)
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Entry Date(s):
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Date Created: 20210329 Date Completed: 20210917 Latest Revision: 20210917
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Update Code:
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20240105
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DOI:
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10.3233/BME-201118
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PMID:
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33780354
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Background: The intricate structure of natural materials is in correspondence with its highly complex functional behaviour. The health of teeth depends, in a complex way, on a heterogeneous arrangement of soft and hard porous tissues that allow for an adequate flow of minerals and oxygen to provide continuous restoration. Although restorative materials, used in clinics, have been evolving from the silver amalgams to actual inorganic fillers, their structural and textural properties are scarcely biomimetic, hindering the functional recovery of the tissue.
Objective: The objective of this work is to compare and test the hybrid mesoporous silica-based scaffolds as candidates for dentine restoration applications.
Methods: In this work, we present the development and the physical properties study of biocompatible hybrid mesoporous nanostructured scaffolds with a chemically versatile surface and biosimilar architecture. We test their textural (BET) and dielectric permittivity (ac impedance) properties.
Results: These materials, with textural and dielectric properties similar to dentine and large availability for the payload of therapeutic agents, are promising candidates as functional restorative materials, suitable for impedance characterization techniques in dental studies.
Conclusions: Structural, textural, morphological characterization and electrical properties of hybrid mesoporous show a large degree of similarity to natural dentin samples.
