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Tytuł:
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Seasonal variation in estimated cardiovascular risk in patients with type 2 diabetes.
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Autorzy:
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Ciardullo S; Department of Medicine and Rehabilitation, Policlinico di Monza, Monza, Italy; School of Medicine and Surgery, University of Milano Bicocca, Milan, Italy.
Muraca E; Department of Medicine and Rehabilitation, Policlinico di Monza, Monza, Italy.
Cannistraci R; Department of Medicine and Rehabilitation, Policlinico di Monza, Monza, Italy; School of Medicine and Surgery, University of Milano Bicocca, Milan, Italy.
Manzoni G; Department of Medicine and Rehabilitation, Policlinico di Monza, Monza, Italy.
Perra S; Department of Medicine and Rehabilitation, Policlinico di Monza, Monza, Italy.
Bianconi E; Department of Medicine and Rehabilitation, Policlinico di Monza, Monza, Italy.
Oltolini A; Department of Medicine and Rehabilitation, Policlinico di Monza, Monza, Italy.
Zerbini F; Department of Medicine and Rehabilitation, Policlinico di Monza, Monza, Italy.
Grassi G; Clinica Medica, University of Milano Bicocca, Milan, Italy.
Mancia G; Department of Medicine and Rehabilitation, Policlinico di Monza, Monza, Italy; School of Medicine and Surgery, University of Milano Bicocca, Milan, Italy.
Lattuada G; Department of Medicine and Rehabilitation, Policlinico di Monza, Monza, Italy.
Perseghin G; Department of Medicine and Rehabilitation, Policlinico di Monza, Monza, Italy; School of Medicine and Surgery, University of Milano Bicocca, Milan, Italy. Electronic address: .
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Źródło:
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Nutrition, metabolism, and cardiovascular diseases : NMCD [Nutr Metab Cardiovasc Dis] 2021 May 06; Vol. 31 (5), pp. 1494-1500. Date of Electronic Publication: 2021 Feb 06.
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Typ publikacji:
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Journal Article; Observational Study; Research Support, Non-U.S. Gov't
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Język:
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English
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Imprint Name(s):
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Publication: 2005- : Amsterdam : Elsevier
Original Publication: [Heidelberg] : Springer International, c1991-
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MeSH Terms:
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Seasons*
Cardiovascular Diseases/*epidemiology
Diabetes Mellitus, Type 2/*epidemiology
Aged ; Cardiovascular Diseases/diagnosis ; Comorbidity ; Diabetes Mellitus, Type 2/diagnosis ; Female ; Heart Disease Risk Factors ; Humans ; Italy/epidemiology ; Male ; Middle Aged ; Prognosis ; Retrospective Studies ; Risk Assessment ; Temperature ; Time Factors
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Contributed Indexing:
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Keywords: Blood pressure; Cardiovascular risk; Diabetes; Risk estimation; Seasons
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Entry Date(s):
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Date Created: 20210403 Date Completed: 20210524 Latest Revision: 20210524
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Update Code:
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20240105
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DOI:
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10.1016/j.numecd.2021.01.022
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PMID:
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33810954
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Background and Aims: Seasonal variations in several risk factors for cardiovascular events (CVD) were described. Here, we evaluate the impact of seasonal variations in blood pressure (BP), lipid profile and glycemic control on estimated CVD risk in patients with type 2 diabetes (T2D).
Methods and Results: Retrospective monocentric study of patients with T2D who were visited at least once in the winter period and once in the summer period, less than 8 months apart, for which data related to systolic (S) BP, diastolic (D) BP, body mass index, glycosylated hemoglobin (HbA1c), total cholesterol, HDL cholesterol and smoking habit were available on both occasions. The 10-year CVD risk was calculated using the UKPDS risk engine and the ASCVD risk estimator. As many as 411 patients were included in the study. Significant within-patient differences between summer and winter were found for the absolute risk of events assessed with both calculators (Δs-w UKPDS-CHD: -1.33%, Δs-w UKPDS-Stroke: -0.84%, Δs-w ASCVD: -2.21%). The seasonal change in SBP was the main responsible for the change in risk estimated with both the UKPDS-Stroke (r 2 = 0.43) and the ASCVD (r 2 = 0.50) scores, while the change in total cholesterol was the main determinant of the change in risk for the UKPDS-CHD (r 2 = 0.34). A significant correlation was identified between changes in temperature and changes in SBP (ρ = 0.130, p = 0.008), but not in other risk factors.
Conclusions: Seasonal variations in the classic CVD risk factors influence the risk estimated using validated calculators.
Competing Interests: Declaration of competing interest All authors declare no conflicts of interest related to this study.
(Copyright © 2021 The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.)
