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Tytuł pozycji:

Correlation between symptoms and imaging findings including pelvic floor ultrasound to improve the symptom-based diagnosis of female urethral diverticulum (CHECK-UD study).

Tytuł :
Correlation between symptoms and imaging findings including pelvic floor ultrasound to improve the symptom-based diagnosis of female urethral diverticulum (CHECK-UD study).
Autorzy :
Barakat B; Department of Urology and Pediatric Urology, Hospital Viersen, Hoserkirchweg 63, 41747, Viersen, Germany. .
Franke K; Department of Urology and Pediatric Urology, Hospital Viersen, Hoserkirchweg 63, 41747, Viersen, Germany.
Hijazi S; Department of Urology, Hospital Ibbenbüren, Ibbenbüren, Germany.
Wolff I; Department of Urology, University Medicine Greifswald, Greifswald, Germany.
Hadaschik B; Department of Urology and Pediatric Urology, University Hospital Essen, Essen, Germany.
Rehme C; Department of Urology and Pediatric Urology, University Hospital Essen, Essen, Germany.
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Źródło :
International urogynecology journal [Int Urogynecol J] 2021 Apr 19. Date of Electronic Publication: 2021 Apr 19.
Publication Model :
Ahead of Print
Typ publikacji :
Journal Article
Język :
English
Imprint Name(s) :
Original Publication: London : Springer
References :
El-Nashar SA, Bacon MM, Kim-Fine S, Weaver AL, Gebhart JB, Klingele CJ. Incidence of female urethral diverticulum: a population-based analysis and literature review. Int Urogynecol J. 2014;25:73–9. (PMID: 10.1007/s00192-013-2155-2)
Stewart M, Bretland PM, Stidolph NE. Urethral diverticula in the adult female. Br J Urol. 1981;53:353–9. (PMID: 10.1111/j.1464-410X.1981.tb03196.x)
Romanzi LJ, Groutz A, Blaivas JG. Urethral diverticulum in women: diverse presentations resulting in diagnostic delay and mismanagement. J Urol. 2000;164:428–4. (PMID: 10.1016/S0022-5347(05)67377-6)
Reeves FA, Inman RD, Chapple CR. Management of symptomatic urethral diverticula in women: a single-centre experience. Eur Urol. 2014;66:164–72. (PMID: 10.1016/j.eururo.2014.02.041)
Stav K, Dwyer PL, Rosamilia A, et al. Urinary symptoms before and after female urethral diverticulectomy—can we predict de novo stress urinary incontinence? J Urol. 2008;180:2088–90. (PMID: 10.1016/j.juro.2008.07.049)
Baradaran N, Chiles L, Freilich DA, Rames RA, Cox L, Rovner RS. Female urethral diverticula in the contemporary era: is the classic triad of the “3Ds” still relevant? Urology. 2016;94:53–6. (PMID: 10.1016/j.urology.2016.04.005)
Aydin A, Ahmed K, Zaman I, Khan MS, Dasgupta P. Recurrent urinary tract infections in women. Int Urogynecol J. 2015;26(6):795–804. (PMID: 10.1007/s00192-014-2569-5)
Abrams P, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U. The standardisation of terminology of lower urinary tract function: report from the standardisation sub-committee of the International Continence Society. Neurourol Urodyn. 2002;21:167–78. (PMID: 10.1002/nau.10052)
Ockrim JL, Allen DJ, Shah PJ, Greenwell TJ. A tertiary experience of urethral diverticulectomy: diagnosis, imaging and surgical outcomes. BJU Int. 2009;103(11):1550–4. (PMID: 10.1111/j.1464-410X.2009.08348.x)
El-Nashar SA, Singh R, Bacon MM, Kim-Fine S, Occhino JA, Gebhart JB, et al. Female urethral diverticulum: presentation, diagnosis, and predictors of outcomes after surgery. Female Pelvic Med Reconstr Surg. 2016;22(6):447–452.9. (PMID: 10.1097/SPV.0000000000000312)
Santoro GA, Wieczorek AP, Dietz HP, Mellgren A, Sultan AH, Shobeiri SA, et al. State of the art: an integrated approach to pelvic floor ultrasonography. Ultrasound Obstet Gynecol. 2011;37(4):381–96. (PMID: 10.1002/uog.8816)
Wieczorek AP, Stankiewicz A, Santoro GA, Woźniak MM, Bogusiewicz M, Rechberger T. Pelvic floor disorders: role of new ultrasonographic techniques. World J Urol. 2011;29(5):615–23. (PMID: 10.1007/s00345-011-0708-x)
Patel AK, Chapple CR. Female urethral diverticula. Curr Opin Urol. 2006;16:248–54. (PMID: 10.1097/01.mou.0000232045.80180.2f)
Contributed Indexing :
Keywords: Female urethral diverticulum; Pelvic floor ultrasound; Symptoms
Entry Date(s) :
Date Created: 20210419 Latest Revision: 20210419
Update Code :
20210419
DOI :
10.1007/s00192-021-04770-6
PMID :
33871666
Czasopismo naukowe
Introduction and Hypothesis: The objective was to establish a model to predict the presence of a female urethral diverticulum (UD) based on symptoms.
Methods: A prospective CHECK-UD study (check of female urethral diverticulum) was conducted. Female patients presenting with symptoms such as lower urinary tract symptoms (LUTS), postmicturition dribble or urinary incontinence (UI), dyspareunia or pain in the pelvic area, and recurrent urinary tract infection (UTI) treated between 2015 and 2020 were included. The association between each symptom variable and the positive finding of UD was evaluated by multivariate logistic regression adjusting for age, body mass index (BMI), vaginal deliveries, previous surgery for SUI, previous pelvic surgery, and microscopic hematuria. A predictive model for the presence of UD was then created.
Results: In total, 189 female patients with a minimum of one symptom were enrolled. Pelvic floor ultrasound revealed the presence of UD in 66 out of 189 (34.92%). Of the four symptoms, the combinations "LUTS + postmicturition dribble + UTI," "postmicturition dribble + LUTS," and "UTI + LUTS" were most significantly related to positive findings and had a higher positive prognostic value for the diagnosis of UD than each individual symptom alone (OR = 13.78 [95% CI: 6.95-16.35], p < 0.001; OR = 9.94 [95% CI: 4.60-12.2], p < 0.05; and OR = 5.78 [95% CI: 1.58-6.98] p = 0.05) respectively.
Conclusion: Based on our model, the combination "LUTS + postmicturition dribble + UTI" seems to be the most sensitive combination of clinical symptoms predicting the positive finding of UD. This model could be used for patient counseling and for the identification of patients with UD.

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