Predictors of Participation in Clinical Research.

Szczegóły
Abstrakt

Tytuł:: Predictors of Participation in Clinical Research.
Autorzy:: Scanlon JK
Wofford L
Fair A
Philippi D
Źródło:: Nursing research [Nurs Res] 2021 Jul-Aug 01; Vol. 70 (4), pp. 289-297.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Język:: English
Imprint Name(s):: Publication: <1998- >: Hagerstown, MD : Lippincott-Ravn Publisher
Original Publication: New York, American Journal of Nursing Co.
MeSH Terms:: Biomedical Research*
Patient Selection*
Trust*
Attitude to Health/*ethnology
Racial Groups/*statistics & numerical data
Black or African American/statistics & numerical data ; Cross-Sectional Studies ; Female ; Humans ; Male ; Middle Aged ; Reproducibility of Results ; Surveys and Questionnaires ; White People/statistics & numerical data ; American Indian or Alaska Native/statistics & numerical data
References:: J Transcult Nurs. 2016 Sep;27(5):456-63. (PMID: 25754929)
BMC Health Serv Res. 2018 Jul 20;18(1):568. (PMID: 30029660)
Med Care. 2006 Nov;44(11):1048-53. (PMID: 17063137)
MMWR Morb Mortal Wkly Rep. 2020 Apr 17;69(15):458-464. (PMID: 32298251)
J Health Care Poor Underserved. 2010 Aug;21(3):879-97. (PMID: 20693733)
J Natl Med Assoc. 2011 Feb;103(2):123-30. (PMID: 21443064)
BMC Med Res Methodol. 2011 Mar 31;11:35. (PMID: 21453543)
J Biomed Inform. 2019 Jul;95:103208. (PMID: 31078660)
Ann Fam Med. 2006 May-Jun;4(3):247-52. (PMID: 16735527)
Genet Med. 2019 Jan;21(1):107-113. (PMID: 29887604)
Am J Bioeth. 2018 Apr;18(4):3-20. (PMID: 29621457)
Gerontologist. 2011 Jun;51 Suppl 1:S106-15. (PMID: 21565812)
J Community Health. 2013 Aug;38(4):642-51. (PMID: 23468319)
J Womens Health (Larchmt). 2014 Aug;23(8):681-7. (PMID: 25046058)
Oncol Nurs Forum. ;44(1):20-23. (PMID: 28060469)
Cancer Nurs. 1993 Feb;16(1):25-33. (PMID: 8457983)
Q J Econ. 2018 Feb;133(1):407-455. (PMID: 30505005)
Am J Health Behav. 2013 Jan;37(1):80-5. (PMID: 22943104)
Milbank Q. 2001;79(4):613-39, v. (PMID: 11789119)
J Clin Epidemiol. 2011 Aug;64(8):872-7. (PMID: 21330104)
J Natl Med Assoc. 1997 Nov;89(11):721-7. (PMID: 9375475)
Cancer Detect Prev. 2006;30(1):24-33. (PMID: 16495020)
Qual Health Res. 2017 Jan;27(1):130-137. (PMID: 26825482)
Soc Work Public Health. 2010 May;25(3):286-95. (PMID: 20446176)
J Mix Methods Res. 2014 Jan 1;8(1):83-106. (PMID: 25309155)
J Community Health. 2017 Jun;42(3):472-480. (PMID: 27812847)
J Nurs Adm. 2010 Jan;40(1):43-8. (PMID: 20010377)
J Health Psychol. 2013 Jan;18(1):65-74. (PMID: 22366042)
J Empir Res Hum Res Ethics. 2014 Oct;9(4):10-21. (PMID: 25747293)
Grant Information:: UL1 TR000445 United States TR NCATS NIH HHS
Entry Date(s):: Date Created: 20210422 Date Completed: 20210824 Latest Revision: 20221207
Update Code:: 20240104
PubMed Central ID:: PMC8231664
DOI:: 10.1097/NNR.0000000000000513
PMID:: 33883501
: Czasopismo naukowe

Background: Despite numerous efforts to create more equitable healthcare systems, minority populations face long-standing health disparities compared to White populations. Healthcare research is the necessary foundation for creating equitable health systems and providing patient-centered care. Significant challenges exist, however, with recruiting and engaging underrepresented populations in clinical research.
Objectives: The purpose of this analysis was to determine how research participants' race, trust, and level of education influence participation barriers in clinical research.
Methods: The study used secondary, cross-sectional survey data that were collected between 2014 and 2016 through the former Mid-South Clinical Data Research Network, currently known as the Stakeholders, Technology, and Research Clinical Research Network. Descriptive statistics and Spearman rank correlations were performed between level of education, level of trust, and each attitude statement for each racial category.
Results: A total of 2,190 survey responses were used in the data analysis. The mean age of respondents was 52 years, with majority being women, White, insured, and working full time. Overall, the respondents had favorable attitudes toward research participation. Trust was correlated with agreement in many attitude statements for both White and African American respondents, whereas correlations with education level were more variable depending on racial grouping. Trust level was negatively associated with agreement toward the statement "researchers do not care about me" in White and Native American respondents.
Discussion: The results support the importance of trust to research participation. Generally, education level was not strongly predictive of research participation, although prediction was influenced by race and attitude.
Competing Interests: The authors have no conflicts of interest to report.
(Copyright © 2021 The Authors. Published by Wolters Kluwer Health, Inc.)

Informacja