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Tytuł:
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Resurgence of SARS-CoV-2: Detection by community viral surveillance.
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Autorzy:
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Riley S; School of Public Health, Imperial College London, London, UK. .; MRC Centre for Global Infectious Disease Analysis and Abdul Latif Jameel Institute for Disease and Emergency Analytics, Imperial College London, London, UK.
Ainslie KEC; School of Public Health, Imperial College London, London, UK.; MRC Centre for Global Infectious Disease Analysis and Abdul Latif Jameel Institute for Disease and Emergency Analytics, Imperial College London, London, UK.
Eales O; School of Public Health, Imperial College London, London, UK.; MRC Centre for Global Infectious Disease Analysis and Abdul Latif Jameel Institute for Disease and Emergency Analytics, Imperial College London, London, UK.
Walters CE; School of Public Health, Imperial College London, London, UK.; MRC Centre for Global Infectious Disease Analysis and Abdul Latif Jameel Institute for Disease and Emergency Analytics, Imperial College London, London, UK.
Wang H; School of Public Health, Imperial College London, London, UK.; MRC Centre for Global Infectious Disease Analysis and Abdul Latif Jameel Institute for Disease and Emergency Analytics, Imperial College London, London, UK.
Atchison C; School of Public Health, Imperial College London, London, UK.
Fronterre C; Centre for Health Informatics, Computing, and Statistics (CHICAS), Lancaster Medical School, Lancaster University, Lancaster, UK.; Health Data Research UK, London, UK.
Diggle PJ; Centre for Health Informatics, Computing, and Statistics (CHICAS), Lancaster Medical School, Lancaster University, Lancaster, UK.; Health Data Research UK, London, UK.
Ashby D; School of Public Health, Imperial College London, London, UK.
Donnelly CA; School of Public Health, Imperial College London, London, UK.; MRC Centre for Global Infectious Disease Analysis and Abdul Latif Jameel Institute for Disease and Emergency Analytics, Imperial College London, London, UK.; Department of Statistics, University of Oxford, Oxford, UK.
Cooke G; Department of Infectious Disease, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, London, UK.; National Institute for Health Research Imperial Biomedical Research Centre, London, UK.
Barclay W; Department of Infectious Disease, Imperial College London, London, UK.
Ward H; School of Public Health, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, London, UK.; National Institute for Health Research Imperial Biomedical Research Centre, London, UK.
Darzi A; Imperial College Healthcare NHS Trust, London, UK.; National Institute for Health Research Imperial Biomedical Research Centre, London, UK.; Institute of Global Health Innovation, Imperial College London, London, UK.
Elliott P; School of Public Health, Imperial College London, London, UK. .; Imperial College Healthcare NHS Trust, London, UK.; National Institute for Health Research Imperial Biomedical Research Centre, London, UK.; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
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Źródło:
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Science (New York, N.Y.) [Science] 2021 May 28; Vol. 372 (6545), pp. 990-995. Date of Electronic Publication: 2021 Apr 23.
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Typ publikacji:
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Journal Article; Research Support, Non-U.S. Gov't
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Język:
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English
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Imprint Name(s):
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Publication: : Washington, DC : American Association for the Advancement of Science
Original Publication: New York, N.Y. : [s.n.] 1880-
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MeSH Terms:
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Epidemiological Monitoring*
Public Health Surveillance*
COVID-19/*epidemiology
Adolescent ; Adult ; Aged ; Basic Reproduction Number ; COVID-19/diagnosis ; COVID-19 Nucleic Acid Testing ; Child ; Child, Preschool ; England/epidemiology ; Female ; Humans ; Male ; Middle Aged ; Pandemics ; Prevalence ; SARS-CoV-2 ; Young Adult
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References:
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Grant Information:
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MC_PC_19012 United Kingdom MRC_ Medical Research Council; MC_PC_20029 United Kingdom MRC_ Medical Research Council; MR/J008761/1 United Kingdom MRC_ Medical Research Council; United Kingdom WT_ Wellcome Trust; MR/R015600/1 United Kingdom MRC_ Medical Research Council
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Entry Date(s):
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Date Created: 20210424 Date Completed: 20210611 Latest Revision: 20240402
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Update Code:
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20240402
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PubMed Central ID:
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PMC8158959
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DOI:
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10.1126/science.abf0874
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PMID:
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33893241
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Surveillance of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has mainly relied on case reporting, which is biased by health service performance, test availability, and test-seeking behaviors. We report a community-wide national representative surveillance program in England based on self-administered swab results from ~594,000 individuals tested for SARS-CoV-2, regardless of symptoms, between May and the beginning of September 2020. The epidemic declined between May and July 2020 but then increased gradually from mid-August, accelerating into early September 2020 at the start of the second wave. When compared with cases detected through routine surveillance, we report here a longer period of decline and a younger age distribution. Representative community sampling for SARS-CoV-2 can substantially improve situational awareness and feed into the public health response even at low prevalence.
(Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.)
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