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Tytuł:
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3D Modeling of Blood Flow in Simulated Abdominal Aortic Aneurysm.
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Autorzy:
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Gonzalez-Urquijo M; Tecnologico de Monterrey, School of Medicine and Health Sciences, Nuevo Leon, Mexico.
de Zamacona RG; Tecnologico de Monterrey, School of Engineering and Sciences, Nuevo Leon, Mexico.
Mendoza AKM; Tecnologico de Monterrey, School of Engineering and Sciences, Nuevo Leon, Mexico.
Iribarren MZ; Tecnologico de Monterrey, School of Engineering and Sciences, Nuevo Leon, Mexico.
Ibarra EG; Tecnologico de Monterrey, School of Engineering and Sciences, Nuevo Leon, Mexico.
Bencomo MDM; Tecnologico de Monterrey, School of Engineering and Sciences, Nuevo Leon, Mexico.
Fabiani MA; Tecnologico de Monterrey, School of Medicine and Health Sciences, Nuevo Leon, Mexico.
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Źródło:
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Vascular and endovascular surgery [Vasc Endovascular Surg] 2021 Oct; Vol. 55 (7), pp. 677-683. Date of Electronic Publication: 2021 Apr 27.
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Typ publikacji:
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Journal Article
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Język:
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English
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Imprint Name(s):
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Publication: Thousand Oaks, CA : Sage Publications
Original Publication: Glen Head, N.Y. : Westminster Publications, c2002-
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MeSH Terms:
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Hemodynamics*
Models, Cardiovascular*
Aorta, Abdominal/*physiopathology
Aortic Aneurysm, Abdominal/*physiopathology
Aorta, Abdominal/diagnostic imaging ; Aortic Aneurysm, Abdominal/complications ; Aortic Aneurysm, Abdominal/diagnostic imaging ; Aortic Rupture/etiology ; Aortic Rupture/physiopathology ; Biomechanical Phenomena ; Blood Flow Velocity ; Finite Element Analysis ; Humans ; Hydrodynamics ; Regional Blood Flow ; Software ; Stress, Mechanical
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Contributed Indexing:
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Keywords: aortic aneurysm; biomechanics; risk rupture; solidworks; wall properties
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Entry Date(s):
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Date Created: 20210427 Date Completed: 20211124 Latest Revision: 20220426
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Update Code:
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20240104
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DOI:
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10.1177/15385744211012926
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PMID:
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33902355
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Background: Besides biological factors, abdominal aortic aneurysm rupture is also caused by mechanical parameters, which are constantly affecting the wall's tissue due to their abnormal values. The ability to evaluate these parameters could vastly improve the clinical treatment of patients with abdominal aortic aneurysms. The objective of this study was to develop and demonstrate a methodology to analyze the fluid dynamics that cause the wall stress distribution in abdominal aortic aneurysms, using accurate 3D geometry and a realistic, nonlinear, elastic biomechanical model using a computer-aided software.
Methods: The geometry of the abdominal aortic aneurysm; was constructed on a 3D scale using computer-aided software SolidWorks (Dassault Systems SolidWorksCorp., Waltham MA). Due to the complex nature of the abdominal aortic aneurysm geometry, the physiological forces and constraints acting on the abdominal aortic aneurysm wall were measured by using a simulation setup using boundary conditions and initial conditions for different studies such as finite element analysis or computational fluid dynamics.
Results: The flow pattern showed an increase velocity at the angular neck, followed by a stagnated flow inside the aneurysm sack. Furthermore, the wall shear stress analysis showed to focalized points of higher stress, the top and bottom of the aneurysm sack, where the flow collides against the wall. An increase of the viscosity showed no significant velocity changed but results in a slight increase in overall pressure and wall shear stress.
Conclusions: Conducting computational fluid dynamics modeling of the abdominal aortic aneurysm using computer-aided software SolidWorks (Dassault Systems SolidWorksCorp., Waltham MA) proves to be an insightful approach for the clinical setting. The careful consideration of the biomechanics of the abdominal aortic aneurysm may lead to an improved, case-specific prediction of the abdominal aortic aneurysm rupture potential, which could significantly improve the clinical management of these patients.
