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Tytuł:
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Higher Long-Term Mortality in Patients with Non-ST-Elevation Myocardial Infarction than ST-Elevation Myocardial Infarction after Discharge.
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Autorzy:
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Han X; Department of Cardiology, Chonnam National University Hospital, Gwangju, Korea.; Department of Cardiology, Yanbian University Hospital, Yanji, China.
Bai L; Department of Cardiology, Chonnam National University Hospital, Gwangju, Korea.; Department of Cardiology, Yanbian University Hospital, Yanji, China.
Jeong MH; Department of Cardiology, Chonnam National University Hospital, Gwangju, Korea. .
Ahn JH; Department of Cardiology, Chonnam National University Hospital, Gwangju, Korea.
Hyun DY; Department of Cardiology, Chonnam National University Hospital, Gwangju, Korea.
Cho KH; Department of Cardiology, Chonnam National University Hospital, Gwangju, Korea.
Kim MC; Department of Cardiology, Chonnam National University Hospital, Gwangju, Korea.
Sim DS; Department of Cardiology, Chonnam National University Hospital, Gwangju, Korea.
Hong YJ; Department of Cardiology, Chonnam National University Hospital, Gwangju, Korea.
Kim JH; Department of Cardiology, Chonnam National University Hospital, Gwangju, Korea.
Ahn Y; Department of Cardiology, Chonnam National University Hospital, Gwangju, Korea.
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Corporate Authors:
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Other KAMIR-NIH Registry Investigators
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Źródło:
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Yonsei medical journal [Yonsei Med J] 2021 May; Vol. 62 (5), pp. 400-408.
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Typ publikacji:
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Journal Article
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Język:
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English
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Imprint Name(s):
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Original Publication: Seoul : Yonsei University
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MeSH Terms:
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Non-ST Elevated Myocardial Infarction*
Percutaneous Coronary Intervention*
ST Elevation Myocardial Infarction*
Aged ; Humans ; Patient Discharge ; Registries ; Republic of Korea/epidemiology ; Risk Factors ; Stroke Volume ; Ventricular Function, Left
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References:
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N Engl J Med. 2015 Sep 24;373(13):1271-2. (PMID: 26398080)
Eur Heart J. 2018 Jan 7;39(2):119-177. (PMID: 28886621)
Circulation. 2000 Oct 24;102(17):2031-7. (PMID: 11044416)
Medicine (Baltimore). 2019 Mar;98(11):e14833. (PMID: 30882670)
Am J Cardiol. 1993 Jan 1;71(1):1-7. (PMID: 8420223)
Lancet. 2015 Jan 31;385(9966):441-51. (PMID: 24969506)
Am J Cardiol. 2004 Jun 15;93(12):1455-60. (PMID: 15194012)
N Engl J Med. 2001 Nov 22;345(21):1573; author reply 1574-5. (PMID: 11794229)
J Transl Med. 2020 Apr 6;18(1):157. (PMID: 32252780)
J Am Coll Cardiol. 2014 Dec 23;64(24):e139-e228. (PMID: 25260718)
Diabet Med. 2001 Dec;18(12):979-83. (PMID: 11903397)
BMJ. 2006 Nov 25;333(7578):1091. (PMID: 17032691)
Am J Cardiol. 2018 Aug 1;122(3):365-373. (PMID: 30041888)
Am J Cardiol. 1998 Jul 1;82(1):38-42. (PMID: 9671006)
PLoS One. 2016 Jul 21;11(7):e0159335. (PMID: 27442587)
Circ J. 2016 May 25;80(6):1427-36. (PMID: 27118621)
Cardiovasc Diabetol. 2011 Oct 31;10:95. (PMID: 22035298)
Int J Cardiol. 2016 Sep 1;218:196-201. (PMID: 27236114)
Eur Heart J. 2007 Jun;28(11):1289-96. (PMID: 17363447)
Arch Intern Med. 2002 Nov 25;162(21):2405-10. (PMID: 12437397)
JAMA. 2000 Aug 16;284(7):835-42. (PMID: 10938172)
Am J Cardiol. 1995 Aug 1;76(4):250-4. (PMID: 7618618)
Aging Dis. 2020 Feb 1;11(1):108-117. (PMID: 32010485)
Am J Cardiol. 2002 Aug 15;90(4):358-63. (PMID: 12161222)
Cardiol Clin. 2018 Feb;36(1):37-52. (PMID: 29173680)
Curr Cardiol Rep. 2014 May;16(5):485. (PMID: 24668607)
BMJ Open. 2014 Feb 21;4(2):e004425. (PMID: 24561498)
Can J Cardiol. 2006 Apr;22(5):399-404. (PMID: 16639475)
Circulation. 1998 Nov 3;98(18):1860-8. (PMID: 9799205)
J Am Coll Cardiol. 2001 May;37(6):1571-80. (PMID: 11345367)
J Am Coll Cardiol. 2012 Oct 16;60(16):1581-98. (PMID: 22958960)
Lancet. 1999 Aug 28;354(9180):708-15. (PMID: 10475181)
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Grant Information:
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2016-ER6304-02 Republic of Korea Korea Centers for Disease Control and Prevention
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Contributed Indexing:
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Keywords: Acute myocardial infarction; prognosis; risk factors
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Entry Date(s):
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Date Created: 20210428 Date Completed: 20210429 Latest Revision: 20210511
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Update Code:
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20240104
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PubMed Central ID:
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PMC8084695
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DOI:
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10.3349/ymj.2021.62.5.400
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PMID:
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33908210
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Purpose: This study aimed to compare mortality rates after discharge between the patients with non-ST-elevation myocardial infarction (NSTEMI) and those with ST-elevation myocardial infarction (STEMI), and identify each mortality risk factors in these two types of myocardial infarction.
Materials and Methods: Between 2011 and 2015, 13105 consecutive patients were enrolled in the Korea Acute Myocardial Infarction-National Institute of Health registry (KAMIR-NIH); 12271 patients with acute myocardial infarction met the inclusion criteria and were further stratified into the STEMI (n=5828) and NSTEMI (n=6443) groups. The occurrence of mortality and cardiac mortality at 3 years were compared between groups, and the factors associated with mortality for NSTEMI and STEMI were evaluated.
Results: The comparison between these two groups and long-term follow-up outcomes showed that the cumulative rates of all-cause and cardiac mortality were higher in the NSTEMI group than in the STEMI group [all-cause mortality: 10.9% vs. 5.8%; hazards ratio (HR), 0.464; 95% confidence interval (CI), 0.359-0.600, p <0.001; cardiac mortality: 6.6% vs. 3.5%, HR, 0.474; 95% CI, 0.344-0.654, p <0.001, respectively). In the NSTEMI group, low left ventricular ejection fraction (LVEF; <40%), no percutaneous coronary intervention (PCI), old age (≥65 years), and low hemoglobin level (<12 g/dL) were identified as risk factors for 3-year mortality. In the STEMI group, old age, low glomerular filtration rate (<60 mL/min/1.73 m²), low LVEF, high heart rate (>100 beats/min), no PCI, and low hemoglobin level were identified as the risk factors for 3-year mortality.
Conclusion: The NSTEMI group had higher mortality compared to the STEMI group during the 3-year clinical follow-up after discharge. Low LVEF and no PCI were the main risk factors for mortality in the NSTEMI group. In contrast, old age and renal dysfunction were the risk factors for long-term mortality in the STEMI group.
Competing Interests: The authors have no potential conflicts of interest to disclose.
(© Copyright: Yonsei University College of Medicine 2021.)
