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Tytuł:
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Comparison of first trimester dating methods for gestational age estimation and their implication on preterm birth classification in a North Indian cohort.
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Autorzy:
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Vijayram R; Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai, India.; Centre for Integrative Biology and Systems Medicine, Indian Institute of Technology Madras, Chennai, India.
Damaraju N; Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai, India.; Centre for Integrative Biology and Systems Medicine, Indian Institute of Technology Madras, Chennai, India.
Xavier A; Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai, India.; Centre for Integrative Biology and Systems Medicine, Indian Institute of Technology Madras, Chennai, India.
Desiraju BK; Maternal and Child Health Program, Translational Health Science and Technology Institute, Faridabad, India.; Interdisciplinary Group for Advanced Research on Birth Outcomes - DBT India Initiative, Translational Health Science and Technology Institute, Faridabad, India.
Thiruvengadam R; Maternal and Child Health Program, Translational Health Science and Technology Institute, Faridabad, India.; Interdisciplinary Group for Advanced Research on Birth Outcomes - DBT India Initiative, Translational Health Science and Technology Institute, Faridabad, India.
Misra S; Maternal and Child Health Program, Translational Health Science and Technology Institute, Faridabad, India.; Interdisciplinary Group for Advanced Research on Birth Outcomes - DBT India Initiative, Translational Health Science and Technology Institute, Faridabad, India.
Chopra S; Maternal and Child Health Program, Translational Health Science and Technology Institute, Faridabad, India.; Interdisciplinary Group for Advanced Research on Birth Outcomes - DBT India Initiative, Translational Health Science and Technology Institute, Faridabad, India.
Khurana A; The Ultrasound Lab, Defence Colony, New Delhi, India.
Wadhwa N; Maternal and Child Health Program, Translational Health Science and Technology Institute, Faridabad, India.; Interdisciplinary Group for Advanced Research on Birth Outcomes - DBT India Initiative, Translational Health Science and Technology Institute, Faridabad, India.
Rengaswamy R; Centre for Integrative Biology and Systems Medicine, Indian Institute of Technology Madras, Chennai, India.; Department of Chemical Engineering, Indian Institute of Technology Madras, Chennai, India.; Robert Bosch Centre for Data Science and Artificial Intelligence, Indian Institute of Technology Madras, Chennai, India.
Sinha H; Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai, India. .; Centre for Integrative Biology and Systems Medicine, Indian Institute of Technology Madras, Chennai, India. .; Robert Bosch Centre for Data Science and Artificial Intelligence, Indian Institute of Technology Madras, Chennai, India. .
Bhatnagar S; Maternal and Child Health Program, Translational Health Science and Technology Institute, Faridabad, India. .; Interdisciplinary Group for Advanced Research on Birth Outcomes - DBT India Initiative, Translational Health Science and Technology Institute, Faridabad, India. .
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Corporate Authors:
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GARBH-Ini Study Group
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Źródło:
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BMC pregnancy and childbirth [BMC Pregnancy Childbirth] 2021 Apr 30; Vol. 21 (1), pp. 343. Date of Electronic Publication: 2021 Apr 30.
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Typ publikacji:
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Comparative Study; Journal Article; Multicenter Study; Observational Study
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Język:
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English
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Imprint Name(s):
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Original Publication: London : BioMed Central, [2001-
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MeSH Terms:
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Crown-Rump Length*
Gestational Age*
Pregnancy Trimester, First*
Premature Birth/*classification
Ultrasonography, Prenatal/*methods
Adult ; Female ; Humans ; India ; Infant, Newborn ; Pregnancy ; Prospective Studies ; Young Adult
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References:
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Indian J Radiol Imaging. 2020 Apr-Jun;30(2):149-155. (PMID: 33100681)
BMC Med Res Methodol. 2013 Dec 07;13:151. (PMID: 24314232)
Lancet Glob Health. 2019 Jan;7(1):e37-e46. (PMID: 30389451)
J Family Med Prim Care. 2019 Jun;8(6):1846-1849. (PMID: 31334143)
Contraception. 2004 Oct;70(4):289-92. (PMID: 15451332)
Am J Epidemiol. 2019 Apr 1;188(4):621-631. (PMID: 30770926)
BJOG. 2014 Apr;121(5):556-65. (PMID: 24387345)
J Obstet Gynaecol Can. 2019 Oct;41(10):1497-1507. (PMID: 31548039)
J Med Imaging Radiat Oncol. 2008 Oct;52(5):471-9. (PMID: 19032393)
Ultrasound Obstet Gynecol. 2008 Apr;31(4):388-96. (PMID: 18348183)
Fertil Steril. 2003 Aug;80(2):259-61. (PMID: 12909481)
Obesity (Silver Spring). 2009 May;17(5):1070-6. (PMID: 19180069)
Obstet Gynecol. 2017 May;129(5):e150-e154. (PMID: 28426621)
Ultrasound Obstet Gynecol. 2009 Feb;33(2):157-60. (PMID: 19115262)
Lancet. 1986 Feb 8;1(8476):307-10. (PMID: 2868172)
Early Hum Dev. 2005 Oct;81(10):833-9. (PMID: 16084037)
Acta Obstet Gynecol Scand. 1977;56(3):247-53. (PMID: 560099)
Acta Paediatr. 2015 Dec;104(467):96-113. (PMID: 26172878)
Am J Obstet Gynecol. 2002 Dec;187(6):1660-6. (PMID: 12501080)
N Engl J Med. 1998 Dec 17;339(25):1817-22. (PMID: 9854117)
Radiology. 1992 Feb;182(2):501-5. (PMID: 1732970)
Lancet. 2014 Sep 6;384(9946):857-68. (PMID: 25209487)
Paediatr Perinat Epidemiol. 2008 Nov;22(6):587-96. (PMID: 19000297)
Int J Gynaecol Obstet. 2019 Jan;144(1):9-15. (PMID: 30267538)
Br J Obstet Gynaecol. 1975 Sep;82(9):702-10. (PMID: 1182090)
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Contributed Indexing:
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Investigator: V Bal; S Bhatnagar; B Das; M Dash; BK Desiraju; P Kshetrapal; S Misra; UCM Natchu; S Rath; K Sachdeva; D Sharma; A Singh; S Sopory; R Thiruvengadam; N Wadhwa; A Maitra; PP Majumder; S Mukherjee; TK Maiti; M Bahl; S Bansal; U Mehta; S Sharma; B Sindhu; S Arya; R Bharti; H Chellani; P Mittal; A Garg; S Ramji; A Khurana; R Tripathi; A Goyal; Y Gupta; S Hari; N Tandon; R Gupta; DM Salunke; GB Nair; G Kang
Keywords: CRL; Crown-rump length; GARBH-Ini; Garbhini-GA1; Gestational age; Last menstrual period; Machine learning; Preterm birth
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Entry Date(s):
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Date Created: 20210501 Date Completed: 20210524 Latest Revision: 20210524
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Update Code:
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20240105
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PubMed Central ID:
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PMC8088008
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DOI:
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10.1186/s12884-021-03807-4
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PMID:
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33931016
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Background: Different formulae have been developed globally to estimate gestational age (GA) by ultrasonography in the first trimester of pregnancy. In this study, we develop an Indian population-specific dating formula and compare its performance with published formulae. Finally, we evaluate the implications of the choice of dating method on preterm birth (PTB) rate. This study's data was from GARBH-Ini, an ongoing pregnancy cohort of North Indian women to study PTB.
Methods: Comparisons between ultrasonography-Hadlock and last menstrual period (LMP) based dating methods were made by studying the distribution of their differences by Bland-Altman analysis. Using data-driven approaches, we removed data outliers more efficiently than by applying clinical parameters. We applied advanced machine learning algorithms to identify relevant features for GA estimation and developed an Indian population-specific formula (Garbhini-GA1) for the first trimester. PTB rates of Garbhini-GA1 and other formulae were compared by estimating sensitivity and accuracy.
Results: Performance of Garbhini-GA1 formula, a non-linear function of crown-rump length (CRL), was equivalent to published formulae for estimation of first trimester GA (LoA, - 0.46,0.96 weeks). We found that CRL was the most crucial parameter in estimating GA and no other clinical or socioeconomic covariates contributed to GA estimation. The estimated PTB rate across all the formulae including LMP ranged 11.27-16.50% with Garbhini-GA1 estimating the least rate with highest sensitivity and accuracy. While the LMP-based method overestimated GA by 3 days compared to USG-Hadlock formula; at an individual level, these methods had less than 50% agreement in the classification of PTB.
Conclusions: An accurate estimation of GA is crucial for the management of PTB. Garbhini-GA1, the first such formula developed in an Indian setting, estimates PTB rates with higher accuracy, especially when compared to commonly used Hadlock formula. Our results reinforce the need to develop population-specific gestational age formulae.
