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Tytuł:
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Relationship Between Central Corneal Thickness and Ganglionic-Inner Plexiform Cell Layer and Retinal Nerve Fibre Layer Thickness in Normal Subjects.
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Autorzy:
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Al Saad M; Department of Special Surgery/Ophthalmology Division, School of Medicine, The University of Jordan, Amman, Jordan.
Shehadeh A; Department of Special Surgery/Ophthalmology Division, School of Medicine, The University of Jordan, Amman, Jordan.
Meqbil J; Department of Special Surgery/Ophthalmology Division, School of Medicine, The University of Jordan, Amman, Jordan.
Elubous K; Department of Special Surgery/Ophthalmology Division, School of Medicine, The University of Jordan, Amman, Jordan.
Qablawi M; Department of Special Surgery/Ophthalmology Division, School of Medicine, The University of Jordan, Amman, Jordan.
Abu-Yaghi N; Department of Special Surgery/Ophthalmology Division, School of Medicine, The University of Jordan, Amman, Jordan.
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Źródło:
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Clinical ophthalmology (Auckland, N.Z.) [Clin Ophthalmol] 2021 Apr 28; Vol. 15, pp. 1809-1812. Date of Electronic Publication: 2021 Apr 28 (Print Publication: 2021).
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Typ publikacji:
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Journal Article
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Język:
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English
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Imprint Name(s):
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Original Publication: Auckland : Dove Medical Press, c2007-
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References:
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J Med Assoc Thai. 2014 Jul;97(7):751-7. (PMID: 25265775)
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Prog Retin Eye Res. 2013 Jan;32:1-21. (PMID: 22995953)
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Contributed Indexing:
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Keywords: central corneal thickness; ganglion cell layer; inner plexiform layer; optical coherence tomography
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Entry Date(s):
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Date Created: 20210506 Latest Revision: 20220422
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Update Code:
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20240104
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PubMed Central ID:
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PMC8090982
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DOI:
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10.2147/OPTH.S308585
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PMID:
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33953540
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Purpose: To determine the relationship between central corneal thickness (CCT), ganglionic cell-inner plexiform layer thickness and macular nerve fibre layer (RNFL) thickness as measured by optical coherence tomography in a cohort of healthy subjects.
Methods: Sixty healthy eyes from 60 subjects were included in this study. All subjects had a standard slit-lamp examination and optical coherence tomography. Central corneal thickness was measured using the Optopol spectral domain optical coherence tomography (SD OCT) machine (version 7.2.0). A linear mixed effects model was used to assess the relationship between central corneal thickness (CCT) and ganglionic cell-inner plexiform layer thickness and macular retinal nerve fibre layer thickness (RNFL).
Results: Sixty healthy eyes from 60 subjects were included in this study. The average age was 41.8 years (±20.6 years). There were 22 males (37%) and 38 females (63%). The average central corneal thickness was 525.2 ± 35.1 µm (451-601) µm. The average macular retinal nerve fiber layer thickness was 28.9 ± 2.5 µm (23-38µm), and the average ganglionic cell-inner plexiform layer thickness was 88.6 ± 6.3 µm (75-110 µm). We found no statistically significant relationship between central corneal thickness and ganglionic cell-inner plexiform layer thickness (p=0.983) nor with macular RNFL (p =0.285).
Conclusion: In this cohort of healthy subjects, there was no statistically significant relationship between central corneal thickness and ganglionic cell-inner plexiform layer thickness or with macular retinal nerve fibre layer thickness.
Competing Interests: The authors reported no conflicts of interest for this work.
(© 2021 Al Saad et al.)
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