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Tytuł:
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How dyspepsia, gastroesophageal reflux symptoms, and overlapping symptoms affect quality of life, use of health care, and medication - a long-term population based cohort study.
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Autorzy:
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Klausen KM; Department of Medical Gastroenterology and Hepatology S, Odense University Hospital, Odense, Denmark.
Bomme Høgh M; Department of Medical Gastroenterology and Hepatology S, Odense University Hospital, Odense, Denmark.
David M; Department of Medical Gastroenterology and Hepatology S, Odense University Hospital, Odense, Denmark.
Schaffalitzky de Muckadell OB; Department of Medical Gastroenterology and Hepatology S, Odense University Hospital, Odense, Denmark.
Hansen JM; Department of Medical Gastroenterology and Hepatology S, Odense University Hospital, Odense, Denmark.
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Źródło:
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Scandinavian journal of gastroenterology [Scand J Gastroenterol] 2021 Jul; Vol. 56 (7), pp. 753-760. Date of Electronic Publication: 2021 Jun 01.
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Typ publikacji:
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Journal Article; Randomized Controlled Trial
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Język:
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English
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Imprint Name(s):
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Publication: London : Informa Healthcare
Original Publication: Oslo : Universitetsforlager
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MeSH Terms:
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Dyspepsia*/drug therapy
Dyspepsia*/epidemiology
Gastroesophageal Reflux*/drug therapy
Gastroesophageal Reflux*/epidemiology
Cohort Studies ; Delivery of Health Care ; Humans ; Quality of Life ; Surveys and Questionnaires
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Contributed Indexing:
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Keywords: Dyspepsia; GERD; GERS; Gastroesophageal Reflux Symptoms; Long-term; Overlapping GERS and Dyspepsia; Population Study; Quality of Life; SF-36; Use of Health Care
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Entry Date(s):
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Date Created: 20210601 Date Completed: 20210818 Latest Revision: 20220424
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Update Code:
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20240105
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DOI:
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10.1080/00365521.2021.1929448
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PMID:
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34062084
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Background and Aim: The prevalence of gastroesophageal reflux symptoms (GERS) and dyspepsia is high. Overlapping of GERS and dyspepsia has been described to affect quality of life. However, studies are few. This long-term population-based study evaluates how GERS, dyspepsia, and overlapping symptoms, affect quality of life, and the use of health care and medication.
Methods: This study presents data for the control group of the randomised population study, HEP-FYN. At baseline 10,000 individuals, aged 40-65 years, received questionnaires at baseline and after 1, 5 and 13 years. The questionnaire included questions regarding demographics, use of health care resources, gastrointestinal symptoms (the Gastrointestinal Symptom Rating Scale (GSRS)), and the Short-Form 36-Item Health Survey (SF-36) to assess quality of life.
Results: Complete data was available for 4.403 individuals at 13-year follow-up. Of these 13.6% reported GERS only, 11.6% dyspepsia only, and 27.1% overlapping symptoms during follow-up. Individuals reporting overlapping symptoms had compared to individuals reporting GERS only or dyspepsia only more visits at general practitioner (last year:16.7% vs. 8.5% vs. 12.3%), more sick leave days (last month: 4.3% vs. 2.9% vs 0.7%), used more ulcer drugs (last month: 30.5% vs 16.4% vs 9.4%). In addition, individuals with overlapping symptoms reported a lower quality of life in all eight dimensions of SF-36 compared to individuals with GERS alone or dyspepsia alone.
Conclusions: Overlapping symptoms was associated with lower quality of life scores and substantial use of health-care resources. Having solely GERS affected quality of life and health care use least.
