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Tytuł pozycji:

[A review on the application of UK Biobank in neuroimaging].

Tytuł:
[A review on the application of UK Biobank in neuroimaging].
Autorzy:
Lin L; Intelligent Physiological Measurement and Clinical Translation, Beijing International Base for Scientific and Technological Cooperation, Department of Biomedical Engineering, Faculty of Environment and Life, Beijing University of Technology, Beijing 100124, P.R.China.
Xiong M; Intelligent Physiological Measurement and Clinical Translation, Beijing International Base for Scientific and Technological Cooperation, Department of Biomedical Engineering, Faculty of Environment and Life, Beijing University of Technology, Beijing 100124, P.R.China.
Wu S; Intelligent Physiological Measurement and Clinical Translation, Beijing International Base for Scientific and Technological Cooperation, Department of Biomedical Engineering, Faculty of Environment and Life, Beijing University of Technology, Beijing 100124, P.R.China.
Źródło:
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi [Sheng Wu Yi Xue Gong Cheng Xue Za Zhi] 2021 Jun 25; Vol. 38 (3), pp. 594-601.
Typ publikacji:
Journal Article; Review
Język:
Chinese
Imprint Name(s):
Publication: Chengdu : Sichuan Sheng sheng wu yi xue gong cheng xue hui
Original Publication: Chengdu : Sichuan Sheng sheng wu yi xue gong cheng xue hui : Hua xi yi ke da xue : Chengdu ke ji da xue,
MeSH Terms:
Biological Specimen Banks*
Neuroimaging*
Brain ; United Kingdom
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Contributed Indexing:
Keywords: UK Biobank; biomedical; brain aging; multimodality magnetic resonance imaging; neuroimaging
Local Abstract: [Publisher, Chinese] 英国生物银行(UKB)是一项前瞻性流行病学研究计划,招募了逾 50 万名年龄在 40~69 岁之间的参与者。其影像扩展项目共邀请了 10 万名 UKB 参与者进行多模态大脑磁共振成像扫描。这些海量的多模态成像与大量的表型、遗传数据结合,为脑健康相关研究领域提供了很好的资源。本文就 UKB 在神经影像领域的研究进展展开综述。首先概括了 UKB 中神经影像的数据采集和影像学衍生表型,随后从心血管疾病风险因素、调节性因素、脑年龄预测、常态、成功和病态脑老化、环境与遗传因素、认知能力及性别等多个应用层面,分别介绍了 UKB 中的一些典型研究,并对研究中存在的问题和未来发展方向进行了探讨,以期为神经系统疾病的预防和治疗开辟新的研究领域。.
Entry Date(s):
Date Created: 20210628 Date Completed: 20210629 Latest Revision: 20230701
Update Code:
20240105
PubMed Central ID:
PMC9927767
DOI:
10.7507/1001-5515.202012059
PMID:
34180206
Czasopismo naukowe
UK Biobank (UKB) is a forward-looking epidemiological project with over 500, 000 people aged 40 to 69, whose image extension project plans to re-invite 100, 000 participants from UKB to perform multimodal brain magnetic resonance imaging. Large-scale multimodal neuroimaging combined with large amounts of phenotypic and genetic data provides great resources to conduct brain health-related research. This article provides an in-depth overview of UKB in the field of neuroimaging. Firstly, neuroimage collection and imaging-derived phenotypes are summarized. Secondly, typical studies of UKB in neuroimaging areas are introduced, which include cardiovascular risk factors, regulatory factors, brain age prediction, normality, successful and morbid brain aging, environmental and genetic factors, cognitive ability and gender. Lastly, the open challenges and future directions of UKB are discussed. This article has the potential to open up a new research field for the prevention and treatment of neurological diseases.

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