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Tytuł:
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Determining the efficacy of low-dose oral benzodiazepine administration and use of wide-bore magnet in assisting claustrophobic patients to undergo MRI brain examination.
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Autorzy:
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Sozio SJ; Penn Medicine, Princeton Medical Center, Department of Imaging, 1 Plainsboro Road, Plainsboro, NJ 08536, USA. Electronic address: .
Bian Y; Rutgers University, Graduate School of Education, 10 Seminary Place, New Brunswick, NJ 08901, USA.
Marshall SJ; Rutgers University, Graduate School of Biomedical Sciences, 675 Hoes Lane West, Piscataway, NJ 08854, USA.
Rivera-Núñez Z; Rutgers University, Environmental and Occupational Health Sciences Institute, 170 Frelinghuysen Road, Piscataway, NJ 08854, USA.
Bacile S; Penn Medicine, Princeton Medical Center, Department of Imaging, 1 Plainsboro Road, Plainsboro, NJ 08536, USA.
Roychowdhury S; Rutgers Robert Wood Johnson Medical School, Department of Radiology, 1 Robert Wood Johnson Place, New Brunswick, NJ 08901, USA.
Youmans DC; Penn Medicine, Princeton Medical Center, Department of Imaging, 1 Plainsboro Road, Plainsboro, NJ 08536, USA.
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Źródło:
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Clinical imaging [Clin Imaging] 2021 Nov; Vol. 79, pp. 289-295. Date of Electronic Publication: 2021 Jun 18.
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Typ publikacji:
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Journal Article
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Język:
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English
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Imprint Name(s):
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Original Publication: [New York, NY] : Elsevier, [c1989-
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MeSH Terms:
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Benzodiazepines*
Magnets*
Brain/diagnostic imaging ; Case-Control Studies ; Humans ; Magnetic Resonance Imaging ; Retrospective Studies
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Contributed Indexing:
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Keywords: Anxiolytic; Brain; Claustrophobia; Magnetic resonance imaging; Wide-bore
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Substance Nomenclature:
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12794-10-4 (Benzodiazepines)
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Entry Date(s):
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Date Created: 20210701 Date Completed: 20210927 Latest Revision: 20210927
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Update Code:
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20240105
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DOI:
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10.1016/j.clinimag.2021.06.013
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PMID:
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34198113
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Purpose: Claustrophobia remains a challenging barrier for a significant number of patients to successfully complete a Magnetic Resonance Imaging (MRI) examination. While use of wide-bore machines and pre-exam administration of a low-dose benzodiazepine are commonly employed, there is little published research to determine which modality is the most efficacious based on the patient's specific degree of claustrophobia. This retrospective case-control study examines the efficacy of using a low-dose oral benzodiazepine and wide-bore magnet to successfully aid the claustrophobic patient in completing an MRI Brain examination.
Methods: 3966 non-contrast MRI brain examinations were considered for this study. The sample was filtered to include only patients who were older than 18 years of age, not currently experiencing symptoms which may hinder MRI examination, and did not undergo any additional MR studies at the time of their exam, resulting in a final sample of 2358 examinations for analysis. Patients were then sub-divided based on severity of claustrophobia and analyzed using logistic regression analysis.
Results: Use of wide-bore magnet increased odds of successfully completing the MRI Brain examination in mild, moderately, and severely claustrophobic patients (OR: 1.79, 95% CI: 1.17-2.75). The administration of pre-examination low-dose oral benzodiazepine increased odds of successfully completing the MRI Brain examination in severely claustrophobic patients (OR: 6.21, 95% CI: 1.63-19.28).
Conclusion: Use of a wide-bore magnet is effective in assisting mild, moderately, and severely claustrophobic patients in completing an MRI Brain exam. However, the efficacy of low-dose oral benzodiazepine is limited to severely claustrophobic patients.
(Copyright © 2021. Published by Elsevier Inc.)
