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Tytuł pozycji:

2021 Update on Diagnostic Markers and Translocation in Salivary Gland Tumors.

Tytuł:
2021 Update on Diagnostic Markers and Translocation in Salivary Gland Tumors.
Autorzy:
Meyer MT; Department of Otorhinolaryngology, Head and Neck Surgery, University of Giessen, Klinikstrasse 33, Ebene -1, 35392 Giessen, Germany.
Watermann C; Department of Otorhinolaryngology, Head and Neck Surgery, University of Giessen, Klinikstrasse 33, Ebene -1, 35392 Giessen, Germany.
Dreyer T; Institute for Pathology, Justus Liebig University, Langhansstrasse 10, 35392 Gießen, Germany.
Ergün S; Institute for Anatomy and Cell Biology, Julius-Maximilians-University Würzburg, Koellikerstrasse 6, 97070 Würzburg, Germany.
Karnati S; Institute for Anatomy and Cell Biology, Julius-Maximilians-University Würzburg, Koellikerstrasse 6, 97070 Würzburg, Germany.
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jun 24; Vol. 22 (13). Date of Electronic Publication: 2021 Jun 24.
Typ publikacji:
Journal Article; Review
Język:
English
Imprint Name(s):
Original Publication: Basel, Switzerland : MDPI, [2000-
MeSH Terms:
Biomarkers, Tumor*
Genetic Predisposition to Disease*
Genetic Testing*/methods
Genetic Testing*/standards
Translocation, Genetic*
Salivary Gland Neoplasms/*diagnosis
Salivary Gland Neoplasms/*genetics
Genetic Association Studies ; Humans ; Neoplasm Grading ; Neoplasm Staging ; Preoperative Care/methods ; Preoperative Care/standards ; Salivary Gland Neoplasms/metabolism ; Salivary Gland Neoplasms/therapy
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Contributed Indexing:
Keywords: adenoid cystic carcinoma (ACC); diagnostic markers; epithelial salivary gland; mucoepidermoid carcinoma; pleomorphic adenoma; salivary gland tumors
Substance Nomenclature:
0 (Biomarkers, Tumor)
Entry Date(s):
Date Created: 20210702 Date Completed: 20210726 Latest Revision: 20210726
Update Code:
20240105
PubMed Central ID:
PMC8269195
DOI:
10.3390/ijms22136771
PMID:
34202474
Czasopismo naukowe
Salivary gland tumors are a rare tumor entity within malignant tumors of all tissues. The most common are malignant mucoepidermoid carcinoma, adenoid cystic carcinoma, and acinic cell carcinoma. Pleomorphic adenoma is the most recurrent form of benign salivary gland tumor. Due to their low incidence rates and complex histological patterns, they are difficult to diagnose accurately. Malignant tumors of the salivary glands are challenging in terms of differentiation because of their variability in histochemistry and translocations. Therefore, the primary goal of the study was to review the current literature to identify the recent developments in histochemical diagnostics and translocations for differentiating salivary gland tumors.
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