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Tytuł:
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Capnocytophaga canimorsus Bloodstream Infection Associated with an Urticarial Exanthem.
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Autorzy:
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Goetzinger JC; Department of Internal Medicine, Section of Rheumatology, Immunology, and Allergy, University of Oklahoma Health Sciences Center, 1100 N. Lindsay, Oklahoma City, OK 73104, USA.
LaGrow AL; Department of Internal Medicine, University of Oklahoma Health Sciences Center, 1100 N. Lindsay, Oklahoma City, OK 73104, USA.
Shibib DR; Department of Pathology and Laboratory Medicine, Oklahoma City VA Health Care System, 921 NE 13th Street, Oklahoma City, OK 73104, USA.; Department of Pathology and Laboratory Medicine, University of Oklahoma Health Sciences Center, 940 Stanton L. Young Blvd, Oklahoma City, OK 73104, USA.
Thind SK; Section of Infectious Diseases, Medical Service, Oklahoma City VA Health Care System, 921 NE 13th Street, Oklahoma City, OK 73104, USA.; Department of Internal Medicine, Section of Infectious Diseases, University of Oklahoma Health Sciences Center, 1100 N. Lindsay, Oklahoma City, OK 73104, USA.
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Źródło:
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Case reports in infectious diseases [Case Rep Infect Dis] 2021 Jun 10; Vol. 2021, pp. 9932170. Date of Electronic Publication: 2021 Jun 10 (Print Publication: 2021).
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Typ publikacji:
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Case Reports
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Język:
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English
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Imprint Name(s):
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Original Publication: Cairo : Hindawi Pub. Corp.
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References:
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Am J Clin Pathol. 1976 Apr;65(4):564-9. (PMID: 1266816)
Antimicrob Agents Chemother. 2000 Nov;44(11):3186-8. (PMID: 11036049)
Eur J Clin Microbiol Infect Dis. 2015 Jul;34(7):1271-80. (PMID: 25828064)
Int J Infect Dis. 2019 May;82:104-105. (PMID: 30877041)
J Med Microbiol. 2008 Jul;57(Pt 7):901-903. (PMID: 18566152)
JAAD Case Rep. 2016 Mar 03;2(2):98-101. (PMID: 27051842)
Arch Intern Med. 1980 May;140(5):657-8. (PMID: 6249227)
Open Forum Infect Dis. 2021 Apr 15;8(7):ofab175. (PMID: 34327254)
J Clin Microbiol. 1989 Feb;27(2):231-5. (PMID: 2915017)
Can J Infect Dis Med Microbiol. 2013 Winter;24(4):209-14. (PMID: 24489563)
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Entry Date(s):
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Date Created: 20210705 Latest Revision: 20240402
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Update Code:
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20240402
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PubMed Central ID:
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PMC8213481
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DOI:
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10.1155/2021/9932170
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PMID:
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34221523
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Background . Capnocytophaga canimorsus is a fastidious, slow-growing, Gram-negative rod that is a commensal bacterium in normal gingival flora of canine and feline species. Infection with the organism may cause disease ranging from flu-like symptoms to disseminated intravascular coagulation (DIC), fulminant sepsis, meningitis, and endocarditis with an overall fatality rate of 6-26%. Risk factors for infection from C. canimorsus include immunosuppression, alcoholism, and asplenia. Case Presentation . We describe an unusual case with a relatively indolent clinical course and an urticarial exanthem in an otherwise young immunocompetent patient with a history of type 1 diabetes. The patient presented to the Emergency Department (ED) with a <1-day history of rhinorrhea, fever, and dyspnea. He met sepsis criteria on initial presentation, but left against medical advice and returned to the ED the following day, with new arthralgias and a diffuse rash, multiple erythematous, tender macules scattered across his trunk and extremities, and tonsillar erythema. He had not taken the doses of the prescribed amoxicillin. Blood cultures two days later signaled positive for growth with the Gram stain showing a Gram-negative rod. Three 7-8 cm tender targetoid lesions with central clearing were identified on the patient's back. The patient reported two nonengorged ticks crawling on his body a week prior and sustaining a dog bite to his ear three weeks before presentation. Ultimately, the organism was identified as C. canimorsus through MALDI-TOF mass spectrometry and additional biochemical testing. He was given appropriate antibiotics and improved clinically thereafter. Despite the patient's bacteremia, he never progressed to fulminant sepsis and followed a mild clinical course with several unusual characteristics. C. canimorsus is an uncommon cause of illness in humans, but is an important pathogen to consider when evaluating a patient with a dog bite, known risk factors, and an urticarial exanthem as empiric treatment may prevent severe outcomes.
Competing Interests: The authors declare no conflicts of interest regarding the publication of this paper.
(Copyright © 2021 John C. Goetzinger et al.)
