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Tytuł:
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Spirometry-based reconstruction of real-time cardiac MRI: Motion control and quantification of heart-lung interactions.
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Autorzy:
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Röwer LM; Department of General Pediatrics, Neonatology and Pediatric Cardiology, University Children's Hospital Düsseldorf, Düsseldorf, Germany.; Department of Diagnostic and Interventional Radiology, Heinrich Heine University, Düsseldorf, Germany.
Uelwer T; Department of Computer Science, Heinrich Heine University, Düsseldorf, Germany.
Hußmann J; Department of General Pediatrics, Neonatology and Pediatric Cardiology, University Children's Hospital Düsseldorf, Düsseldorf, Germany.; Department of Diagnostic and Interventional Radiology, Heinrich Heine University, Düsseldorf, Germany.
Malik H; Department of General Pediatrics, Neonatology and Pediatric Cardiology, University Children's Hospital Düsseldorf, Düsseldorf, Germany.; Department of Diagnostic and Interventional Radiology, Heinrich Heine University, Düsseldorf, Germany.
Eichinger M; Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thoraxklinik, University of Heidelberg, Heidelberg, Germany.; Department of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Heidelberg, Germany.; Translational Lung Research Center Heidelberg, German Center for Lung Research, Heidelberg, Germany.
Voit D; Biomedizinische NMR, Max-Planck Institute for Biophysical Chemistry, Göttingen, Germany.
Wielpütz MO; Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thoraxklinik, University of Heidelberg, Heidelberg, Germany.; Department of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Heidelberg, Germany.; Translational Lung Research Center Heidelberg, German Center for Lung Research, Heidelberg, Germany.
Frahm J; Biomedizinische NMR, Max-Planck Institute for Biophysical Chemistry, Göttingen, Germany.; Partner Site Göttingen, German Centre for Cardiovascular Research, Berlin, Germany.
Harmeling S; Department of Computer Science, Heinrich Heine University, Düsseldorf, Germany.
Klee D; Department of Diagnostic and Interventional Radiology, Heinrich Heine University, Düsseldorf, Germany.
Pillekamp F; Department of General Pediatrics, Neonatology and Pediatric Cardiology, University Children's Hospital Düsseldorf, Düsseldorf, Germany.
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Źródło:
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Magnetic resonance in medicine [Magn Reson Med] 2021 Nov; Vol. 86 (5), pp. 2692-2702. Date of Electronic Publication: 2021 Jul 17.
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Typ publikacji:
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Journal Article; Research Support, Non-U.S. Gov't
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Język:
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English
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Imprint Name(s):
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Publication: 1999- : New York, NY : Wiley
Original Publication: San Diego : Academic Press,
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MeSH Terms:
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Magnetic Resonance Imaging, Cine*
Ventricular Function, Left*
Adult ; Cross-Sectional Studies ; Humans ; Lung/diagnostic imaging ; Magnetic Resonance Imaging ; Retrospective Studies ; Spirometry ; Stroke Volume
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References:
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Ferrigno M, Hickey DD, Linér MH, Lundgren CE. Cardiac performance in humans during breath holding. J Appl Physiol. 1986;60:1871-1877.
Magder S. Heart-Lung interaction in spontaneous breathing subjects: the basics. Ann Transl Med. 2018;18:348.
Paulev P, Wetterqvist H. Cardiac output during breath-holding in man. Scand J Clin Lab Invest. 1968;22:115-123.
Scott AD, Keegan J, Firmin DN. Motion in cardiovascular MR imaging. Radiology. 2009;250:331-351.
Uecker M, Zhang S, Voit D, Karaus A, Merboldt KD, Frahm J. Real-time MRI at a resolution of 20 ms. NMR Biomed. 2010;23:986-994.
Voit D, Zhang S, Unterberg-Buchwald C, Sohns JM, Lotz J, Frahm J. Real-time cardiovascular magnetic resonance at 1.5 T using balanced SSFP and 40 ms resolution. J Cardiovasc Magn Reson. 2013;15:79.
Frahm J, Voit D, Uecker M. Real-time magnetic resonance imaging: radial gradient-echo sequences with nonlinear inverse reconstruction. Invest Radiol. 2019;54:757-766.
Zhang S, Joseph AA, Voit D, et al. Real-time magnetic resonance imaging of cardiac function and flow-recent progress. Quant Imaging Med Surg. 2014;4:313-329.
Bauer RW, Radtke I, Block KT, et al. True real-time cardiac MRI in free breathing without ECG synchronization using a novel sequence with radial k-space sampling and balanced SSFP contrast mode. Int J Cardiovasc Imaging. 2013;29:1059-1067.
Eichinger M, Puderbach M, Smith H-J, et al. Magnetic-resonance-compatible-spirometry: principle, technical evaluation and application. Eur Respir J. 2007;30:972-979.
Kokki T, Klén R, Noponen T, et al. Linear relation between spirometric volume and the motion of cardiac structures: MRI and clinical PET study. J Nucl Cardiol. 2016;23:475-485.
Chen S, Hu P, Gu Y, et al. Impact of patient comfort on diagnostic image quality during PET/MR exam: a quantitative survey study for clinical workflow management. J Appl Clin Med Phys. 2019;20:184-192.
Harris CR, Millman KJ, van der Walt SJ, et al. Array programming with NumPy. Nature. 2020;585:357-362.
Mason D, scaramallion, rhaxton, et al. Pydicom/pydicom: V1. 4. 0. January 20, 2020. Zenodo. Available at: https://doi.org/10.5281/zenodo.3614042. Accessed September 15, 2020.
Schulz-Menger J, Bluemke DA, Bremerich J, et al. Standardized image interpretation and post processing in cardiovascular magnetic resonance: society for cardiovascular magnetic resonance (SCMR) board of trustees task force on standardized post processing. J Cardiovasc Magn Reson. 2013;15:35.
Paknezhad M, Marchesseau S, Brown MS. Automatic basal slice detection for cardiac analysis. J Med Imaging (Bellingham). 2016;3:034004.
Marchesseau S, Ho JXM, Totman JJ. Influence of the short-axis cine acquisition protocol on the cardiac function evaluation: a reproducibility study. Eur J Radiol Open. 2016;3:60-66.
van der Ven JPG, Sadighy Z, Valsangiacomo Buechel ER, et al. Multicentre reference values for cardiac magnetic resonance imaging derived ventricular size and function for children aged 0-18 years. Eur Heart J Cardiovasc Imaging. 2020;21:102-113.
Shahzadi I, Siddiqui MF, Aslam I, Omer H. Respiratory motion compensation using data binning in dynamic contrast enhanced golden-angle radial MRI. Magn Reson Imaging. 2020;70:115-125.
Dasari P, Johnson K, Dey J, et al. MRI investigation of the linkage between respiratory motion of the heart and markers on patient‘s abdomen and chest: implications for respiratory amplitude binning list-mode PET and SPECT studies. IEEE Trans Nucl Sci. 2014;61:192-201.
Gay SB, Sistrom CL, Holder CL, Suratt PM. Breath-holding capability of adults. Implications for spiral computed tomography, fast-acquisition magnetic resonance imaging, and angiography. Invest Radiol. 1994;29:848-851.
Funk E, Thunberg P, Anderzen-Carlsson A. Patients’ experiences in magnetic resonance imaging (MRI) and their experiences of breath holding techniques. J Adv Nurs. 2014;70:1880-1890.
Runge VM, Richter JK, Heverhagen JT. Motion in magnetic resonance: new paradigms for improved clinical diagnosis. Invest Radiol. 2019;54:383-395.
Santelli C, Nezafat R, Goddu B, et al. Respiratory bellows revisited for motion compensation: preliminary experience for cardiovascular MR. Magn Reson Med. 2011;65:1097-1102.
Ryan T, Petrovic O, Dillon J, Feigenbaum H, Conley MJ, Armstrong WF. An echocardiographic index for separation of right ventricular volume and pressure overload. J Am Coll Cardiol. 1985;5:918-927.
Guyton AC, Lindsey AW, Abernathy B, Richardson T. Venous return at various right atrial pressures and the normal venous return curve. Am J Physiol. 1957;189:609-615.
Shuler RH, Ensor C, Ginning RE, Moss WG, Johnson V. The differential effects of respiration on the left and right ventricles. Am J Physiol. 1942;137:620-627.
Claessen G, Claus P, Delcroix M, Bogaert J, La Gerche A, Heidbuchel H. Interaction between respiration and right versus left ventricular volumes at rest and during exercise: a real-time cardiac magnetic resonance study. Am J Physiol Heart Circ Physiol. 2014;306:H816-H824.
Korperich H, Barth P, Gieseke J, et al. Impact of respiration on stroke volumes in paediatric controls and in patients after Fontan procedure assessed by MR real-time phase-velocity mapping. Eur Heart J Cardiovasc Imaging. 2015;16:198-209.
Ruskin J, Bache RJ, Rembert JC, Greenfield JC Jr. Pressure-flow studies in man: effect of respiration on left ventricular stroke volume. Circulation. 1973;48:79-85.
Wise RA, Robotham JL, Summer WR. Effects of spontaneous ventilation on the circulation. Lung. 1981;159:175-186.
Summer WR, Permutt S, Sagawa K, Shoukas AA, Bromberger-Barnea B. Effects of spontaneous respiration on canine left ventricular function. Circ Res. 1979;45:719-728.
Delicce AV, Markaryus AN. Physiology, Frank Starling Law. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2020.
Frank O. Zur Dynamik des Herzmuskels. Ztschr Biol. 1895;32:370.
Starling EH. The linacre lecture on the law of the heart. Given at Cambridge, 1915. Nature. 1918;101:1-27.
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Contributed Indexing:
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Keywords: cardiac magnetic resonance imaging; computer-assisted methods; free-breathing examinations; heart diagnostic imaging; image processing; real-time imaging; respiration; spirometry
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Entry Date(s):
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Date Created: 20210717 Date Completed: 20211026 Latest Revision: 20211026
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Update Code:
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20240105
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DOI:
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10.1002/mrm.28892
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PMID:
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34272760
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Purpose: To test the feasibility of cardiac real-time MRI in combination with retrospective gating by MR-compatible spirometry, to improve motion control, and to allow quantification of respiratory-induced changes during free-breathing.
Methods: Cross-sectional real-time MRI (1.5T; 30 frames/s) using steady-state free precession contrast during free-breathing was combined with MR-compatible spirometry in healthy adult volunteers (n = 4). Retrospective binning assigned images to classes that were defined by electrocardiogram and spirometry. Left ventricular eccentricity index as an indicator of septal position and ventricular volumes in different respiratory phases were calculated to assess heart-lung interactions.
Results: Real-time MRI with MR-compatible spirometry is feasible and well tolerated. Spirometry-based binning improved motion control significantly. The end-diastolic epicardial eccentricity index increased significantly during inspiration (1.04 ± 0.04 to 1.19 ± 0.05; P < .05). During inspiration, right ventricular end-diastolic volume (79 ± 17 mL/m 2 to 98 ± 18 mL/m 2 ), stroke volume (41 ± 8 mL/m 2 to 59 ± 11 mL/m 2 ) and ejection fraction (53 ± 3% to 60 ± 1%) increased significantly, whereas the end-systolic volume remained almost unchanged. Left ventricular end-diastolic volume, left ventricular stroke volume, and left ventricular ejection fraction decreased during inspiration, whereas the left ventricular end-systolic volume increased. The relationship between stroke volume and end-diastolic volume (Frank-Starling relationship) based on changes induced by respiration allowed for a slope estimate of the Frank-Starling curve to be 0.9 to 1.1.
Conclusion: Real-time MRI during free-breathing combined with MR-compatible spirometry and retrospective binning improves image stabilization, allows quantitative image analysis, and importantly, offers unique opportunities to judge heart-lung interactions.
(© 2021 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals LLC on behalf of International Society for Magnetic Resonance in Medicine.)