The evaluation of lung involvement and functional capacities in patients diagnosed with primary Sjogren's syndrome.
Sahin Ozdemirel T; Department of Pulmonology, Atatürk Chest Diseases and Chest Surgery Training and Research Hospital, University of Health Sciences, Ankara, Turkey.
Ozdemirel AE; Department of Rheumatology, Gaziler Physical Therapy and Rehabilitation Training and Research Hospital, University of Health Sciences, Ankara, Turkey.
Akinci Ozyurek B; Department of Pulmonology, Atatürk Chest Diseases and Chest Surgery Training and Research Hospital, University of Health Sciences, Ankara, Turkey.
Yenibertiz D; Department of Pulmonology, Kecioren Training and Research Hospital, University of Health Sciences, Ankara, Turkey.
Erdogan Y; Department of Pulmonology, Atatürk Chest Diseases and Chest Surgery Training and Research Hospital, University of Health Sciences, Ankara, Turkey.
International journal of clinical practice [Int J Clin Pract] 2021 Oct; Vol. 75 (10), pp. e14635. Date of Electronic Publication: 2021 Aug 06.
Typ publikacji :
Imprint Name(s) :
Publication: 2003- : Oxford, U.K. : Wiley
Original Publication: Esher [England] ; Bronxville, N.Y. : Medicom International, c1997-
MeSH Terms :
Female ; Humans ; Lung/diagnostic imaging ; Male ; Respiratory Function Tests ; Retrospective Studies ; Tomography, X-Ray Computed
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Entry Date(s) :
Date Created: 20210726 Date Completed: 20210921 Latest Revision: 20210921
Update Code :
Introduction: Sjögren syndrome (SS) is a chronic, systemic, inflammatory disease characterised with lymphocytic infiltration of the exocrine glands, frequently manifested by dryness in the region affected. Although the most common extraglandular involvement in SS is pulmonary involvement. Early diagnosis and treatment is considered to be important. It was aimed to evaluate the frequency of early lung involvement, high resolution computed tomography (HRCT) findings and data of pulmonary function test (PFT) in SS in this study.
Materials and Methods: Thirty-five patients diagnosed with SS and referred by the Department of Rheumatology to determine potential lung involvement to the eighth chest diseases outpatient clinic of our hospital between September 2015 and December 2018 were included in this study. Respiratory signs, demographic features, length of disease and treatment regimens, PFT, data of 6-minute walk test and findings of HRCT of the patients were retrospectively obtained from hospital information system and patient files.
Results: The mean age of the patients was 54.4 ± 9.2. The majority of the patients were women (94.3%). When the HRCT findings were evaluated, 28 (80%) patients had CT findings, while 7 (20%) patients had no CT findings. The most common HRCT findings found in patients were peribronchial thickening (48.6%), ground glass appearance (28.6%) and prominence in interstitial scars.
Conclusion: We think that the evaluation of HRCT and PFTs in patients diagnosed with SS for assessing early pulmonary involvement will be guiding in terms of follow-up and treatment.
(© 2021 John Wiley & Sons Ltd.)