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Tytuł pozycji:

Effect of the Timing of Admission of Out of Hospital Cardiac Arrest Complicating Acute Myocardial Infarction on Management and Outcome.

Tytuł:
Effect of the Timing of Admission of Out of Hospital Cardiac Arrest Complicating Acute Myocardial Infarction on Management and Outcome.
Autorzy:
Dafaalla M; Keele Cardiovascular Research Group, School of Medicine, Keele University, Stoke-on-Trent, United Kingdom; Department of cardiology, Royal Stoke University Hospital, Stoke-on-Trent, United Kingdom.
Rashid M; Keele Cardiovascular Research Group, School of Medicine, Keele University, Stoke-on-Trent, United Kingdom; Department of cardiology, Royal Stoke University Hospital, Stoke-on-Trent, United Kingdom.
Weston C; Glangwili General Hospital, Carmarthen, Wales, United Kingdom.
D'Ascenzo F; Division of Cardiology, Department of Medical Sciences, University of Turino, Turino, Italy.
De Ferrari GM; Division of Cardiology, A.O.U. Città della Salute e della Scienza di Torino, Torino, Italy.
Hussain ST; University Hospitals of Leicester NHS Trust, Leicester, United Kingdom.
Mohamed MO; Keele Cardiovascular Research Group, School of Medicine, Keele University, Stoke-on-Trent, United Kingdom; Department of cardiology, Royal Stoke University Hospital, Stoke-on-Trent, United Kingdom.
Shoaib A; Keele Cardiovascular Research Group, School of Medicine, Keele University, Stoke-on-Trent, United Kingdom; Department of cardiology, Royal Stoke University Hospital, Stoke-on-Trent, United Kingdom.
Curzen N; Coronary Research Group, University Hospital Southampton NHS Trust and Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
Mamas MA; Keele Cardiovascular Research Group, School of Medicine, Keele University, Stoke-on-Trent, United Kingdom; Department of cardiology, Royal Stoke University Hospital, Stoke-on-Trent, United Kingdom; Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania.. Electronic address: .
Źródło:
The American journal of cardiology [Am J Cardiol] 2021 Oct 01; Vol. 156, pp. 1-8. Date of Electronic Publication: 2021 Aug 02.
Typ publikacji:
Journal Article; Multicenter Study
Język:
English
Imprint Name(s):
Original Publication: New York, NY : Excerpta Medica
MeSH Terms:
Disease Management*
Time-to-Treatment*
Myocardial Infarction/*complications
Out-of-Hospital Cardiac Arrest/*therapy
Aged ; Angioplasty, Balloon, Coronary ; Female ; Hospital Mortality/trends ; Humans ; Male ; Middle Aged ; Myocardial Infarction/mortality ; Myocardial Infarction/surgery ; Out-of-Hospital Cardiac Arrest/etiology ; Out-of-Hospital Cardiac Arrest/mortality ; Percutaneous Coronary Intervention ; Risk Factors ; Survival Rate/trends ; Treatment Outcome ; United Kingdom/epidemiology
Entry Date(s):
Date Created: 20210806 Date Completed: 20210920 Latest Revision: 20210920
Update Code:
20240105
DOI:
10.1016/j.amjcard.2021.06.042
PMID:
34353630
Czasopismo naukowe
There is limited data regarding the impact of time of admission on clinical outcomes of out of hospital cardiac arrest (OHCA) complicating acute myocardial infarction (AMI). We investigated the patient characteristics, management, and outcomes of OHCA complicating AMI according to the time of admission. Patients admitted with a diagnosis of AMI and OHCA between 2010 and 2017 from the Myocardial Ischemia National Audit Project (MINAP) were studied. All patients were stratified into out-of-hours (OOH) and working hours (WH) cohort according to the time of hospital admission. We used multivariable logistic regression models to evaluate the predictors of clinical outcomes and treatment strategy. 16,118 patients were admitted with AMI and OHCA. The WH cohort consisted of 5,780 patients (35.9%) and OOH cohort consisted of 10,338 patients (64.1%). The OOH cohort was younger (OOH 64 vs WH 66 years, p <0.001). A significantly higher proportion of patients had a final diagnosis of STEMI in OOH cohort (OOH 78.3% vs WH 76.6%, p = 0.012). Whilst the use of coronary angiography was lower in OOH (OOH 80.7% vs WH 82.5%, p = 0.005), PCI rates were similar (OOH 39.7% vs WH 40.5%, p = 0.4). Adjusted in-hospital mortality (OR 0.96, 95%CI 0.86 to 1.07), re-infarction (OR 0.90, 95% CI 0.72 to 1.12) and bleeding (OR 0.93, 95% CI 0.76 to 1.12) were similar in the 2 groups. In conclusion, the majority of OHCA occurred out of working hours. However, the time of hospital admission didn't affect the rate of revascularization by PCI or clinical outcomes.
(Copyright © 2021 Elsevier Inc. All rights reserved.)

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