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Tytuł pozycji:

Impact of intravascular ultrasound on Outcomes following PErcutaneous coronary interventioN for In-stent Restenosis (iOPEN-ISR study).

Tytuł:
Impact of intravascular ultrasound on Outcomes following PErcutaneous coronary interventioN for In-stent Restenosis (iOPEN-ISR study).
Autorzy:
Shlofmitz E; Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, USA.
Torguson R; Department of Cardiovascular Research and Clinical Trials, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Zhang C; Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, USA.
Mintz GS; Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, USA.
Dheendsa A; Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, USA.
Khalid N; Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, USA.
Chen Y; Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, USA.
Musallam A; Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, USA.
Rogers T; Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, USA; Cardiovascular Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Hashim H; Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, USA.
Ben-Dor I; Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, USA.
Garcia-Garcia HM; Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, USA.
Waksman R; Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, USA. Electronic address: .
Źródło:
International journal of cardiology [Int J Cardiol] 2021 Oct 01; Vol. 340, pp. 17-21. Date of Electronic Publication: 2021 Aug 08.
Typ publikacji:
Journal Article
Język:
English
Imprint Name(s):
Publication: Amsterdam : Elsevier
Original Publication: Amsterdam : Elsevier/North-Holland Biomedical Press, c1981-
MeSH Terms:
Coronary Artery Disease*
Coronary Restenosis*/diagnostic imaging
Coronary Restenosis*/etiology
Drug-Eluting Stents*
Percutaneous Coronary Intervention*/adverse effects
Coronary Angiography ; Humans ; Treatment Outcome ; Ultrasonography, Interventional
Contributed Indexing:
Keywords: Drug-eluting stent; In-stent restenosis; Intravascular ultrasound
Entry Date(s):
Date Created: 20210809 Date Completed: 20211020 Latest Revision: 20211020
Update Code:
20240105
DOI:
10.1016/j.ijcard.2021.08.003
PMID:
34371029
Czasopismo naukowe
Background: Percutaneous coronary intervention (PCI) for in-stent restenosis (ISR) remains common. Intravascular imaging allows for the determination of the mechanism of ISR, potentially guiding appropriate therapy. Intravascular ultrasound (IVUS)-guided stent implantation is associated with a reduction in adverse events after PCI, but its impact on treatment of ISR is not clear.
Methods: All patients with 1-year follow-up after ISR treatment from 2003 through 2016 were included and stratified by IVUS use. The primary endpoint was the rate of major adverse cardiac events (MACE) at 1 year, defined as the composite of all-cause mortality, Q-wave myocardial infarction, and target vessel revascularization (TVR).
Results: The final analysis included 1522 ISR patients, 65.9% of whom were treated with IVUS guidance. The primary endpoint occurred in 18.0% of patients treated with IVUS guidance vs. 24.5% of patients treated with angiography guidance (p = 0.0014). Post-dilatation was used more often with IVUS (18.6% vs. 14.1%, p < 0.001), with a larger diameter of new stents (3.04 ± 0.35 mm vs. 2.94 ± 0.47 mm, p = 0.001). At 1 year, TVR occurred in 14.5% with IVUS guidance and 19.2% with angiography guidance (p = 0.021).
Conclusions: The use of IVUS is associated with decreased MACE at 1 year following PCI for ISR. These results support routine IVUS for the treatment of ISR lesions.
(Copyright © 2021. Published by Elsevier B.V.)
Comment in: Int J Cardiol. 2021 Oct 1;340:22-23. (PMID: 34454963)

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