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Tytuł:
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Nesfatin-1 in lipid metabolism and lipid-related diseases.
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Autorzy:
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Luo JJ; Institute of Pharmacy and Pharmacology, School of Pharmaceutical Sciences, University of South China, Hengyang 421001, China; Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang 421001, China.
Wen FJ; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, Department of Cell Biology and Geneties, University of South China, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, Hengyang Medical College, University of South China, Hengyang, Hunan 421001, China.
Qiu D; Institute of Pharmacy and Pharmacology, School of Pharmaceutical Sciences, University of South China, Hengyang 421001, China; Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang 421001, China.
Wang SZ; Institute of Pharmacy and Pharmacology, School of Pharmaceutical Sciences, University of South China, Hengyang 421001, China; Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang 421001, China. Electronic address: .
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Źródło:
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Clinica chimica acta; international journal of clinical chemistry [Clin Chim Acta] 2021 Nov; Vol. 522, pp. 23-30. Date of Electronic Publication: 2021 Aug 10.
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Typ publikacji:
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Journal Article; Review
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Język:
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English
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Imprint Name(s):
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Original Publication: Amsterdam, Elsevier.
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MeSH Terms:
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Calcium-Binding Proteins*
Lipid Metabolism*
DNA-Binding Proteins ; Humans ; Lipids ; Nerve Tissue Proteins ; Nucleobindins
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Contributed Indexing:
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Keywords: Cardiovascular diseases; Fat accumulation; Lipid metabolism; Metabolic syndrome; Nesfatin-1; Obesity
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Substance Nomenclature:
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0 (Calcium-Binding Proteins)
0 (DNA-Binding Proteins)
0 (Lipids)
0 (Nerve Tissue Proteins)
0 (Nucleobindins)
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Entry Date(s):
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Date Created: 20210814 Date Completed: 20210928 Latest Revision: 20210928
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Update Code:
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20240105
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DOI:
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10.1016/j.cca.2021.08.005
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PMID:
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34389280
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Nesfatin-1, an anorexic neuropeptide discovered in 2006, is widely distributed in the central nervous system and peripheral tissues. It has been shown to be involved in the regulation of food intake and lipid metabolism, inhibiting fat accumulation, accelerating lipid decomposition, and in general, inhibiting the development of lipid-related diseases, such as obesity and metabolic syndrome. Potential mechanisms of Nesfatin-1 action in lipid metabolism and lipid-related diseases will be discussed as well as its role as a biomarker in cardiovascular disease. This review expected to provide a new strategy for the diagnosis and prevention of clinically related diseases.
(Copyright © 2021 Elsevier B.V. All rights reserved.)
