Prognostic factors of patients after liver cancer surgery: Based on Surveillance, Epidemiology, and End Results database.

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Tytuł:: Prognostic factors of patients after liver cancer surgery: Based on Surveillance, Epidemiology, and End Results database.
Autorzy:: Liang F; Department of Medical Oncology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, P.R. China.
Ma F
Zhong J
Źródło:: Medicine [Medicine (Baltimore)] 2021 Jul 30; Vol. 100 (30), pp. e26694.
Typ publikacji:: Journal Article
Język:: English
Imprint Name(s):: Original Publication: Hagerstown, Md : Lippincott Williams & Wilkins
MeSH Terms:: Prognosis*
Liver Neoplasms/*surgery
Aged ; Female ; Humans ; Male ; Middle Aged ; Proportional Hazards Models ; SEER Program/statistics & numerical data ; Survival Analysis
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Entry Date(s):: Date Created: 20210816 Date Completed: 20210824 Latest Revision: 20210825
Update Code:: 20240104
PubMed Central ID:: PMC8322491
DOI:: 10.1097/MD.0000000000026694
PMID:: 34397696
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Abstract: This study aimed to investigate the prognostic factors of patients after liver cancer surgery and evaluate the predictive power of nomogram. Liver cancer patients with the history of surgery in the Surveillance, Epidemiology, and End Results database between 2000 and 2016 were preliminary retrieved. Patients were divided into the survival group (n = 2120, survival ≥5 years) and the death group (n = 2615, survival < 5 years). Single-factor and multi-factor Cox regression were used for analyzing the risk factors of death in patients with liver cancer after surgery. Compared with single patients, married status was the protective factor for death in patients undergoing liver cancer surgery (HR = 0.757, 95%CI: 0.685-0.837, P < .001); the risk of death in Afro-Americans (HR = 1.300, 95%CI: 1.166-1.449, P < .001) was higher than that in Caucasians, while the occurrence of death in Asians (HR = 0.821, 95%CI: 0.1754-0.895, P < .0012) was lower; female patients had a lower incidence of death (HR = 0.875, 95%CI: 0.809-0.947, P < .001); grade II (HR = 1.167, 95%CI: 1.080-1.262, P < .001), III (HR = 1.580, 95%CI: 1.433-1.744, P < .001), and IV (HR = 1.419, 95%CI: 1.145-1.758, P = 0.001) were the risk factors for death in patients with liver cancer. The prognostic factors of liver cancer patients after surgery include the marital status, race, gender, age, grade of cancer and tumor size. The nomogram with good predictive ability can provide the prediction of 5-year survival for clinical development.
Competing Interests: The authors have no funding and conflicts of interest to disclose.
(Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.)

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