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Tytuł:
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Prominent gallbladder enlargement: Kawasaki disease or other congenital or acquired gallbladder disease? A case report.
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Autorzy:
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Zhao L; Department of Paediatric Cardiology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.; The Cardiac Development and Early Intervention Unit, West China Institute of Women and Children's Health, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.; Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education Chengdu, Sichuan, China.; Key Laboratory of Development and Diseases of Women and Children of Sichuan Province, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Hua Y; Department of Paediatric Cardiology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.; The Cardiac Development and Early Intervention Unit, West China Institute of Women and Children's Health, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.; Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education Chengdu, Sichuan, China.; Key Laboratory of Development and Diseases of Women and Children of Sichuan Province, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Zhou K; Department of Paediatric Cardiology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.; The Cardiac Development and Early Intervention Unit, West China Institute of Women and Children's Health, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.; Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education Chengdu, Sichuan, China.; Key Laboratory of Development and Diseases of Women and Children of Sichuan Province, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
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Źródło:
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The Journal of international medical research [J Int Med Res] 2021 Sep; Vol. 49 (9), pp. 3000605211041507.
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Typ publikacji:
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Case Reports; Journal Article
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Język:
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English
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Imprint Name(s):
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Publication: Nov. 2012- : London : Sage Publications
Original Publication: Northampton, Eng., Cambridge Medical Publications ltd.
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MeSH Terms:
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Gallbladder Diseases*/diagnostic imaging
Gallbladder Diseases*/drug therapy
Mucocutaneous Lymph Node Syndrome*/diagnostic imaging
Mucocutaneous Lymph Node Syndrome*/drug therapy
Child, Preschool ; Fever ; Humans ; Immunoglobulins, Intravenous/therapeutic use ; Male
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References:
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Contributed Indexing:
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Keywords: Kawasaki disease; case report; computed tomography; gallbladder; glucocorticoid therapy; pediatric
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Substance Nomenclature:
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0 (Immunoglobulins, Intravenous)
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Entry Date(s):
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Date Created: 20210909 Date Completed: 20210910 Latest Revision: 20210917
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Update Code:
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20240105
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PubMed Central ID:
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PMC8442496
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DOI:
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10.1177/03000605211041507
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PMID:
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34496644
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Kawasaki disease (KD) is a common systemic vasculitis in childhood that can result in damage to multiple body systems. However, prominent gallbladder (GB) enlargement in the acute stage is especially rare. A 5-year-old boy was admitted to the hospital with an 8-day history of a cervical mass, 7-day history of fever, and 5-day history of abdominal pain and rash. The child was diagnosed with KD. After treatment with high-dose intravenous immunoglobulin therapy (2 g/kg), all clinical manifestations were relieved except the abdominal pain. Enhanced computed tomography showed distinct enlargement of the GB, and a congenital choledochal cyst was strongly suspected. After high-dose glucocorticoid treatment, his obviously enlarged GB returned to normal size in the subacute phase. No abnormality was found during 2 years of follow-up. Prominent GB enlargement may emerge in the acute stage of KD. The enlarged GB can return to normal size within the subacute stage by standard treatment for KD. Proper diagnosis, thorough differential diagnosis, and active anti-inflammatory treatment of KD are crucial to avoid surgery.
