-
Tytuł:
-
Extraperitoneal laparoscopy for para-aortic lymphadenectomy in endometrial carcinoma staging: an approach with higher efficiency.
-
Autorzy:
-
Zhang W; Department of Gynecologic Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Xia L; Department of Gynecologic Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Han X; Department of Gynecologic Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Ju X; Department of Gynecologic Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Wu X; Department of Gynecologic Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Chen X; Department of Gynecologic Oncology, Fudan University Shanghai Cancer Center, Shanghai, China. .
-
Źródło:
-
World journal of surgical oncology [World J Surg Oncol] 2021 Nov 07; Vol. 19 (1), pp. 323. Date of Electronic Publication: 2021 Nov 07.
-
Typ publikacji:
-
Journal Article
-
Język:
-
English
-
Imprint Name(s):
-
Original Publication: London : BioMed Central, 2003-
-
MeSH Terms:
-
Endometrial Neoplasms*/pathology
Endometrial Neoplasms*/surgery
Laparoscopy*
China ; Female ; Humans ; Lymph Node Excision ; Lymph Nodes/pathology ; Lymph Nodes/surgery ; Neoplasm Staging ; Prognosis ; Retrospective Studies
-
References:
-
Gynecol Oncol. 2001 Sep;82(3):498-503. (PMID: 11520146)
J Minim Invasive Gynecol. 2018 May - Jun;25(4):730-736. (PMID: 29229578)
Gynecol Oncol. 2010 Nov;119(2):291-4. (PMID: 20708226)
Minerva Med. 2021 Feb;112(1):70-80. (PMID: 33198443)
Cancer. 2011 May 1;117(9):1928-34. (PMID: 21509770)
Gynecol Oncol. 2011 May 1;121(2):314-8. (PMID: 21315429)
Int J Gynecol Cancer. 2014 Sep;24(7):1292-8. (PMID: 24987919)
J Clin Oncol. 2009 Nov 10;27(32):5331-6. (PMID: 19805679)
Int J Gynecol Cancer. 2015 Oct;25(8):1494-502. (PMID: 26270116)
Anticancer Res. 2018 Aug;38(8):4677-4681. (PMID: 30061235)
J Minim Invasive Gynecol. 2013 Sep-Oct;20(5):611-5. (PMID: 23680520)
Gynecol Oncol. 2009 Oct;115(1):172-174. (PMID: 19450870)
Gynecol Oncol. 2014 Jan;132(1):98-101. (PMID: 24231134)
Gynecol Oncol. 2019 Jun;153(3):676-683. (PMID: 30952370)
Gynecol Oncol. 1996 Aug;62(2):169-73. (PMID: 8751545)
J Laparoendosc Surg. 1995 Apr;5(2):85-90. (PMID: 7612948)
Gynecol Oncol. 2015 Nov;139(2):330-7. (PMID: 26407477)
Cancer. 2000 Apr 15;88(8):1883-91. (PMID: 10760766)
J Am Coll Surg. 2003 Aug;197(2):198-205. (PMID: 12892797)
Int J Gynecol Cancer. 2011 Jul;21(5):864-9. (PMID: 21666486)
Minim Invasive Ther Allied Technol. 2020 Aug;29(4):232-239. (PMID: 31169418)
Int J Gynecol Cancer. 2015 Feb;25(2):192. (PMID: 25611895)
Lancet Oncol. 2017 Mar;18(3):384-392. (PMID: 28159465)
J Minim Invasive Gynecol. 2015 Feb;22(2):268-74. (PMID: 25460316)
Ann Surg Oncol. 2016 Sep;23(9):2966-74. (PMID: 27098143)
Gynecol Oncol. 2008 Dec;111(3):418-24. (PMID: 18835020)
Gynecol Oncol. 2014 Feb;132(2):366-71. (PMID: 24361579)
Gynecol Oncol. 2008 Apr;109(1):11-8. (PMID: 18304622)
Obstet Gynecol. 1998 Mar;91(3):360-3. (PMID: 9491860)
-
Grant Information:
-
81602270 Young Scientists Fund
-
Contributed Indexing:
-
Keywords: Endometrial carcinoma; Extraperitoneal; Laparotomy; Lymphadenectomy; Minimally invasive; Transperitoneal
-
Entry Date(s):
-
Date Created: 20211108 Date Completed: 20211109 Latest Revision: 20211111
-
Update Code:
-
20240105
-
PubMed Central ID:
-
PMC8573921
-
DOI:
-
10.1186/s12957-021-02416-x
-
PMID:
-
34743715
-
Background: Removing more inframesenteric nodes is not only significantly increases the likelihood of finding metastasis for endometrial cancer, but also can add survival advantage. As most patients diagnosed with endometrial cancer are overweight or obesity, a high efficiency approach is important. Aim of this study was to compare the surgical outcomes of extraperitoneal laparoscopic, transperitoneal laparoscopic, and laparotomic para-aortic lymphadenectomy in endometrial carcinoma staging.
Methods: We retrospectively reviewed data of all patients diagnosed with primary endometrial carcinoma who were treated at the Department of Gynecologic Oncology, Fudan University Shanghai Cancer Center from 1 January 2017 to 31 December 2019. The numbers of para-aortic lymph nodes, surgical time, complications, blood loss and hospital stay were compared. The patients' medical records and pathological reports were carefully reviewed. Statistical significance was defined as p < 0.05.
Results: We retrospectively compared patients who underwent extraperitoneal laparoscopy (Group E, n = 20), transperitoneal laparoscopy (group T, n = 21), and laparotomy (group L, n = 135). The median number of para-aortic lymph nodes was significantly higher in group E than in groups T and L (9.5, 5, and 6, respectively; p = 0.004 and 0.0004, respectively). All patients in group E underwent successfully dissection to the renal vessel level. The median operation time was significantly shorter in group L than in groups T and E (94, 174, and 233 min, respectively; p < 0.0001). The median estimated blood loss volume was higher in group L than in groups T and E (200, 100, and 142.5 ml, respectively; all comparisons p < 0.001), and the length of hospital stay was significantly longer in group L than in Groups T and E (6, 5, and 6 days, respectively; all comparisons p < 0.001).
Conclusion: The extraperitoneal laparoscopic approach for staging endometrial carcinoma harvested higher numbers of para-aortic lymph nodes which could be considered for endometrial carcinoma staging, especially for para-aortic lymph node harvest.
(© 2021. The Author(s).)
Zaloguj się, aby uzyskać dostęp do pełnego tekstu.