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Tytuł:
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Biocatalytic Approaches for an Efficient and Sustainable Preparation of Polyphenols and Their Derivatives.
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Autorzy:
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Contente ML; Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, via Celoria 2, 20133 Milan, Italy.
Annunziata F; Department of Pharmaceutical Sciences (DISFARM), University of Milan, via Mangiagalli 25, 20133 Milan, Italy.
Cannazza P; Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, via Celoria 2, 20133 Milan, Italy.
Donzella S; Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, via Celoria 2, 20133 Milan, Italy.
Pinna C; Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, via Celoria 2, 20133 Milan, Italy.
Romano D; Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, via Celoria 2, 20133 Milan, Italy.
Tamborini L; Department of Pharmaceutical Sciences (DISFARM), University of Milan, via Mangiagalli 25, 20133 Milan, Italy.
Barbosa FG; Department of Organic and Inorganic Chemistry, Sciences Center, Federal University of Ceará, Fortaleza-CE 60455-970, Brazil.
Molinari F; Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, via Celoria 2, 20133 Milan, Italy.
Pinto A; Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, via Celoria 2, 20133 Milan, Italy.
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Źródło:
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Journal of agricultural and food chemistry [J Agric Food Chem] 2021 Nov 24; Vol. 69 (46), pp. 13669-13681. Date of Electronic Publication: 2021 Nov 11.
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Typ publikacji:
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Journal Article; Review
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Język:
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English
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Imprint Name(s):
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Original Publication: Washington, American Chemical Society.
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MeSH Terms:
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Dietary Supplements*
Polyphenols*/analysis
Biocatalysis ; Diet ; Humans ; Vegetables
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Contributed Indexing:
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Keywords: biocatalysis; cosmetics; enzymes; food ingredients; metabolites; nutraceuticals; nutrients
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Substance Nomenclature:
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0 (Polyphenols)
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Entry Date(s):
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Date Created: 20211111 Date Completed: 20211125 Latest Revision: 20211125
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Update Code:
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20240105
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DOI:
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10.1021/acs.jafc.1c05088
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PMID:
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34762407
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Many sectors of industry, such as food, cosmetics, nutraceuticals, and pharmaceuticals, have increased their interest in polyphenols due to their beneficial properties. These molecules are widely found in Nature (plants) and can be obtained through direct extraction from vegetable matrices. Polyphenols introduced through the diet may be metabolized in the human body via different biotransformations leading to compounds having different bioactivities. In this context, enzyme-catalyzed reactions are the most suitable approach to produce modified polyphenols that not only can be studied for their bioactivity but also can be labeled as green, natural products. This review aims to give an overview of the potential of biocatalysis as a powerful tool for the modification of polyphenols to enhance their bioaccessibility, bioavailability, biological activity or modification of their physicochemical properties. The main polyphenol transformations occurring during their metabolism in the human body have been also presented.