Eclipta prostrata (L.) L. (Asteraceae): Ethnomedicinal Uses, Chemical Constituents, and Biological Activities.

Szczegóły
Abstrakt

Tytuł:: Eclipta prostrata (L.) L. (Asteraceae): Ethnomedicinal Uses, Chemical Constituents, and Biological Activities.
Autorzy:: Timalsina D; Central Department of Chemistry, Tribhuvan University, Kathmandu 44618, Nepal.
Devkota HP; Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-Ku, Kumamoto 862-0973, Japan.; Headquarters for Admissions and Education, Kumamoto University, 2-40-1 Kurokami, Chuo-Ku, Kumamoto 860-8555, Japan.
Źródło:: Biomolecules [Biomolecules] 2021 Nov 22; Vol. 11 (11). Date of Electronic Publication: 2021 Nov 22.
Typ publikacji:: Journal Article; Review
Język:: English
Imprint Name(s):: Original Publication: Basel, Switzerland : MDPI, 2011-
MeSH Terms:: Eclipta*
Asteraceae ; Medicine, Traditional
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Contributed Indexing:: Keywords: Eclipta alba; Eclipta prostrata; ecalbasaponin; hepatoprotective; wedelolactone
Entry Date(s):: Date Created: 20211127 Date Completed: 20220112 Latest Revision: 20231108
Update Code:: 20240104
PubMed Central ID:: PMC8615741
DOI:: 10.3390/biom11111738
PMID:: 34827736
: Czasopismo naukowe

Pełny tekst

Eclipta prostrata (L.) L. (Syn.: Eclipta alba (L.) Hassak, Family: Asteraceae) is an important medicinal plant in the tropical and subtropical regions. It is widely used in treating various diseases of skin, liver and stomach in India, Nepal, Bangladesh, and other countries. The main aim of this review was to collect and analyze the available information on traditional uses, phytoconstituents, and biological activities of E. prostrata . The scientific information was collected from the online bibliographic databases such as Scopus, MEDLINE/PubMed, Google Scholar, SciFinder, etc. and books and proceedings. The active phytochemicals were coumestan derivatives, phenolic acid derivatives, flavonoids, triterpenoid and steroid saponins, substituted thiophenes, etc. Various extracts and isolated compounds of E. prostrata showed a wide range of biological activities such as antimicrobial, anticancer, hepatoprotective, neuroprotective and hair growth promoting activities. Relatively a few studies have been performed to reveal the exact phytoconstituents responsible for their corresponding pharmacological activities. Future studies should focus on detailed mechanism based studies using animal models and clinical studies.

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