-
Tytuł:
-
ASYMPTOTICALLY INDEPENDENT U-STATISTICS IN HIGH-DIMENSIONAL TESTING.
-
Autorzy:
-
He Y; Department of Statistics, University of Michigan.
Xu G; Department of Statistics, University of Michigan.
Wu C; Department of Statistics, Florida State University.
Pan W; Division of Biostatistics, School of Public Health, University of Minnesota.
-
Źródło:
-
Annals of statistics [Ann Stat] 2021 Feb; Vol. 49 (1), pp. 154-181. Date of Electronic Publication: 2021 Jan 29.
-
Typ publikacji:
-
Journal Article
-
Język:
-
English
-
Imprint Name(s):
-
Publication: Ithaca, NY : Project Euclid
Original Publication: San Francisco.
-
References:
-
Genetics. 2016 Jun;203(2):715-31. (PMID: 27075728)
Genetics. 2014 Aug;197(4):1081-95. (PMID: 24831820)
Alzheimers Dement. 2011 Mar;7(2):208-44. (PMID: 21414557)
Nucleic Acids Res. 2010 Jan;38(Database issue):D355-60. (PMID: 19880382)
Natl Sci Rev. 2014 Jun;1(2):293-314. (PMID: 25419469)
Nat Genet. 2019 Mar;51(3):404-413. (PMID: 30617256)
Genet Epidemiol. 2009 Dec;33(8):700-9. (PMID: 19333968)
Nature. 2010 Sep 23;467(7314):460-4. (PMID: 20827270)
Biometrika. 2015 Jun;102(2):247-266. (PMID: 28502988)
Alzheimers Dement. 2013 Jan;9(1):63-75.e2. (PMID: 23305823)
Biometrika. 2016 Sep;103(3):609-624. (PMID: 28804142)
Science. 2009 Oct 16;326(5951):399-403. (PMID: 19833961)
Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9440-5. (PMID: 12883005)
Ann Stat. 2021 Feb;49(1):154-181. (PMID: 34857975)
Annu Rev Econom. 2011 Sep;3:291-317. (PMID: 22022635)
Nature. 2009 Oct 8;461(7265):747-53. (PMID: 19812666)
Genomics. 2011 Jul;98(1):1-8. (PMID: 21565265)
Natl Vital Stat Rep. 2018 Jul;67(5):1-76. (PMID: 30248015)
Nature. 2011 Oct 26;478(7370):519-23. (PMID: 22031444)
Genet Epidemiol. 2017 Nov;41(7):599-609. (PMID: 28714590)
J Am Stat Assoc. 2015 Jun 1;110(510):837-849. (PMID: 26279594)
Econometrica. 2015 Jul 1;83(4):1497-1541. (PMID: 26778846)
-
Grant Information:
-
R01 GM113250 United States GM NIGMS NIH HHS; R01 GM126002 United States GM NIGMS NIH HHS; R01 HL105397 United States HL NHLBI NIH HHS; R01 HL116720 United States HL NHLBI NIH HHS
-
Contributed Indexing:
-
Keywords: 62F03; 62F05; High-dimensional hypothesis test; U-statistics; adaptive testing
-
Entry Date(s):
-
Date Created: 20211203 Latest Revision: 20240404
-
Update Code:
-
20240404
-
PubMed Central ID:
-
PMC8634550
-
DOI:
-
10.1214/20-aos1951
-
PMID:
-
34857975
-
Many high-dimensional hypothesis tests aim to globally examine marginal or low-dimensional features of a high-dimensional joint distribution, such as testing of mean vectors, covariance matrices and regression coefficients. This paper constructs a family of U-statistics as unbiased estimators of the ℓ p -norms of those features. We show that under the null hypothesis, the U-statistics of different finite orders are asymptotically independent and normally distributed. Moreover, they are also asymptotically independent with the maximum-type test statistic, whose limiting distribution is an extreme value distribution. Based on the asymptotic independence property, we propose an adaptive testing procedure which combines p -values computed from the U-statistics of different orders. We further establish power analysis results and show that the proposed adaptive procedure maintains high power against various alternatives.