-
Tytuł:
-
Risk factors for systemic reactions in typical cold urticaria: Results from the COLD-CE study.
-
Autorzy:
-
Bizjak M; Division of Allergy, Urticaria Center of Reference and Excellence (UCARE), University Clinic of Respiratory and Allergic Diseases Golnik, Golnik, Slovenia.; Faculty of Medicine, University of Maribor, Maribor, Slovenia.
Košnik M; Division of Allergy, Urticaria Center of Reference and Excellence (UCARE), University Clinic of Respiratory and Allergic Diseases Golnik, Golnik, Slovenia.; Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Dinevski D; Faculty of Medicine, University of Maribor, Maribor, Slovenia.
Thomsen SF; Department of Dermatology, Urticaria Center of Reference and Excellence (UCARE), Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Fomina D; Urticaria Center of Reference and Excellence (UCARE), Center of Allergy and Immunology, Clinical State Hospital 52, Moscow Ministry of Healthcare, Moscow, Russian Federation.; Department of Clinical Immunology and Allergology, I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation.
Borzova E; Department of Dermatology and Venereology, I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation.; Department of Clinical Genetics, Veltischev Research and Clinical Institute for Pediatrics of the Pirogov Russian National Research Medical University, Moscow, Russian Federation.
Kulthanan K; Department of Dermatology, Urticaria Center of Reference and Excellence (UCARE), Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Meshkova R; Department of Clinical Immunology and Allergology, Urticaria Center of Reference and Excellence (UCARE), Smolensk State Medical University, Smolensk, Russian Federation.
Ahsan DM; Urticaria Center of Reference and Excellence (UCARE), Institute for Allergology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology, Berlin, Germany.
Al-Ahmad M; Microbiology Department, Faculty of Medicine, Urticaria Center of Reference and Excellence (UCARE), Kuwait University, Safat, Kuwait.
Altrichter S; Urticaria Center of Reference and Excellence (UCARE), Institute for Allergology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology, Berlin, Germany.; Department of Dermatology and Venerology, Urticaria Center of Reference and Excellence (UCARE), Comprehensive Allergy Center, Kepler University Hospital, Linz, Austria.
Bauer A; Department of Dermatology, Urticaria Center of Reference and Excellence (UCARE), University Allergy Center, University Hospital Carl Gustav Carus, Technical University, Dresden, Germany.
Brockstädt M; Urticaria Center of Reference and Excellence (UCARE), Institute for Allergology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology, Berlin, Germany.
Costa C; Immunoallergology Department, Urticaria Center of Reference and Excellence (UCARE), Hospital de Santa Maria, CHULN, Lisbon, Portugal.
Demir S; Division of Allergy, Department of Internal Medicine, Istanbul Faculty of Medicine, Urticaria Center of Reference and Excellence (UCARE), Istanbul University, Istanbul, Turkey.
Fachini Criado R; Faculdade de Medicina do ABC (FMABC), Urticaria Center of Reference and Excellence (UCARE), Santo André, Brazil.
Ensina LF; Division of Allergy, Clinical Immunology and Rheumatology, Department of Pediatrics, Urticaria Center of Reference and Excellence (UCARE), Federal University of São Paulo, São Paulo, Brazil.
Gelincik A; Division of Allergy, Department of Internal Medicine, Istanbul Faculty of Medicine, Urticaria Center of Reference and Excellence (UCARE), Istanbul University, Istanbul, Turkey.
Giménez-Arnau AM; Department of Dermatology, Urticaria Center of Reference and Excellence (UCARE), Hospital del Mar, IMIM, Universitat Autònoma, Barcelona, Spain.
Gonçalo M; Clinic of Dermatology, Urticaria Center of Reference and Excellence (UCARE), University Hospital and Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
Gotua M; Center of Allergy and Immunology, Urticaria Center of Reference and Excellence (UCARE), Tbilsi, Georgia.
Holm JG; Department of Dermatology, Urticaria Center of Reference and Excellence (UCARE), Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Inomata N; Department of Environmental Immuno-Dermatology, Urticaria Center of Reference and Excellence (UCARE), Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Kasperska-Zajac A; Clinical Department of Internal Diseases, European Center for Diagnosis and Treatment of Urticaria, Urticaria Center of Reference and Excellence (UCARE), Dermatology and Allergology of Medical University of Silesia, Zabrze, Poland.
Khoshkhui M; Allergy Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Klyucharova A; Department of Clinical Immunology and Allergology, Republican Center of Clinical Immunology and Allergology, Urticaria Center of Reference and Excellence (UCARE), Republican Clinical Hospital, Kazan State Medical University, Kazan, Russian Federation.; Department of Fundamental Principles of Clinical Medicine, Institute of Fundamental Medicine and Biology (IFMB) of Kazan Federal University, Kazan, Russian Federation.
Kocatürk E; Department of Dermatology, Urticaria Center of Reference and Excellence (UCARE), Koç University School of Medicine, Istanbul, Turkey.
Lu R; Department of Dermatology, Urticaria Center of Reference and Excellence (UCARE), The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Makris M; Allergy Unit, Second Department of Dermatology and Venereology, Urticaria Center of Reference and Excellence (UCARE), National and Kapodistrian University of Athens, University General Hospital 'Attikon', Athens, Greece.
Maltseva N; Urticaria Center of Reference and Excellence (UCARE), Center of Allergy and Immunology, Clinical State Hospital 52, Moscow Ministry of Healthcare, Moscow, Russian Federation.
Miljković J; Faculty of Medicine, University of Maribor, Maribor, Slovenia.
Pasali M; Allergy Unit, Second Department of Dermatology and Venereology, Urticaria Center of Reference and Excellence (UCARE), National and Kapodistrian University of Athens, University General Hospital 'Attikon', Athens, Greece.
Paulino M; Immunoallergology Department, Urticaria Center of Reference and Excellence (UCARE), Hospital de Santa Maria, CHULN, Lisbon, Portugal.
Pesqué D; Department of Dermatology, Urticaria Center of Reference and Excellence (UCARE), Hospital del Mar, IMIM, Universitat Autònoma, Barcelona, Spain.
Peter J; Division of Allergy and Clinical Immunology, Department of Medicine, Urticaria Center of Reference and Excellence (UCARE), University of Cape Town, Cape Town, South Africa.; Allergy and Immunology Unit, University of Cape Town Lung Institute, Cape Town, South Africa.
Ramón GD; Urticaria Center of Reference and Excellence (UCARE), Instituto de Alergia e Inmunologia del Sur, Buenos Aires, Argentina.
Ritchie C; Adults and Pediatrics Allergy Unit, Urticaria Center of Reference and Excellence (UCARE), Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
Rodrigues Valle SO; Department of Internal Medicine, Immunology Service, Urticaria Center of Reference and Excellence (UCARE), Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Rudenko M; Urticaria Center of Reference and Excellence (UCARE), London Allergy and Immunology Centre, London, UK.
Sikora A; Clinical Department of Internal Diseases, European Center for Diagnosis and Treatment of Urticaria, Urticaria Center of Reference and Excellence (UCARE), Dermatology and Allergology of Medical University of Silesia, Zabrze, Poland.
de Souza Lima EM; Faculdade de Ciências, Médicas e da Saúde de Juiz de Fora (SUPREMA), Urticaria Center of Reference and Excellence (UCARE), Hospital Maternidade Therezinha de Jesus, Minas Gerais, Brazil.
Wagner N; Department of Dermatology, Urticaria Center of Reference and Excellence (UCARE), University Hospital of Erlangen, University of Erlangen-Nuremberg (FAU), Germany.
Xepapadaki P; Allergy Unit, 2nd Pediatric Clinic, Urticaria Center of Reference and Excellence (UCARE), National and Kapodistrian University of Athens, Greece.
Xue X; Department of General Practice, Urticaria Center of Reference and Excellence (UCARE), Community Health Service Center, Guangzhou City, China.
Zhao Z; Department of Dermatology and Venerology, Urticaria Center of Reference and Excellence (UCARE), Beijing Key Laboratory of Molecular Diagnosis on Dermatoses and National Clinical Research Center for Skin and Immune Diseases, Peking University First Hospital, Beijing, China.
Terhorst-Molawi D; Urticaria Center of Reference and Excellence (UCARE), Institute for Allergology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology, Berlin, Germany.
Maurer M; Urticaria Center of Reference and Excellence (UCARE), Institute for Allergology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology, Berlin, Germany.
-
Źródło:
-
Allergy [Allergy] 2022 Jul; Vol. 77 (7), pp. 2185-2199. Date of Electronic Publication: 2021 Dec 23.
-
Typ publikacji:
-
Journal Article
-
Język:
-
English
-
Imprint Name(s):
-
Publication: Copenhagen : Wiley-Blackwell
Original Publication: Copenhagen, Munksgaard.
-
MeSH Terms:
-
Angioedema*/diagnosis
Angioedema*/epidemiology
Angioedema*/etiology
Chronic Urticaria*
Hymenoptera*
Insect Bites and Stings*/complications
Urticaria*/diagnosis
Urticaria*/epidemiology
Urticaria*/etiology
Animals ; Cold Temperature ; Cross-Sectional Studies ; Humans ; Pruritus/complications ; Risk Factors
-
References:
-
Maltseva N, Borzova E, Fomina D, et al. Cold urticaria - what we know and what we do not know. Allergy. 2021;76(4):1077-1094.
Bizjak M, Kosnik M, Terhorst-Molawi D, Dinevski D, Maurer M. Cold agglutinins and cryoglobulins associate with clinical and laboratory parameters of cold urticaria. Front Immunol. 2021;12:665491.
Bizjak M, Maurer M, Košnik MTerhorst-Molawi DZver SBurmeister TSiebenhaar F. Severe cold urticaria can point to an underlying clonal mast cell disorder. Allergy. 2021 Aug; 76(8):2609-2613. doi:10.1111/all.14844. Epub 2021 May 5. PMID: 33797762.
Magerl M, Altrichter S, Borzova E, et al. The definition, diagnostic testing, and management of chronic inducible urticarias - the EAACI/GA(2) LEN/EDF/UNEV consensus recommendations 2016 update and revision. Allergy. 2016;71(6):780-802.
Siebenhaar F, Staubach P, Metz M, Magerl M, Jung J, Maurer M. Peltier effect-based temperature challenge: an improved method for diagnosing cold urticaria. J Allergy Clin Immunol. 2004;114(5):1224-1225.
Magerl M, Abajian M, Krause K, Altrichter S, Siebenhaar F, Church MK. An improved Peltier effect-based instrument for critical temperature threshold measurement in cold- and heat-induced urticaria. J Eur Acad Dermatol Venereol. 2015;29(10):2043-2045.
Metz M, Scholz E, Ferran M, Izquierdo I, Gimenez-Arnau A, Maurer M. Rupatadine and its effects on symptom control, stimulation time, and temperature thresholds in patients with acquired cold urticaria. Ann Allergy Asthma Immunol. 2010;104(1):86-92.
Muraro A, Roberts G, Worm M, et al. Anaphylaxis: guidelines from the European Academy of Allergy and Clinical Immunology. Allergy. 2014;69(8):1026-1045.
Željko T, Sinkovič A. Anaphylactic shock after Ranitidine - a case report. Acta Medico-Biotechnica. 2010;3(1):51-55. Online access to the journal: http://actamedbio.mf.um.si/sl; Online access to this cited manuscript: http://actamedbio.mf.um.si/revija/article/Anafilakti%C4%8Dni+%C5%A1ok+po+Ranitidinu+%E2%80%93+poro%C4%8Dilo+o+primeru_342.
Shaker MS, Wallace DV, Golden DBK, et al. Anaphylaxis-a 2020 practice parameter update, systematic review, and Grading of Recommendations, Assessment, Development and Evaluation (GRADE) analysis. J Allergy Clin Immunol. 2020;145(4):1082-1123.
Ewan P, Brathwaite N, Leech S, et al. BSACI guideline: prescribing an adrenaline auto-injector. Clin Exp Allergy. 2016;46(10):1258-1280.
Ring J, Behrendt H. Anaphylaxis and anaphylactoid reactions. Classification and pathophysiology. Clin Rev Allergy Immunol. 1999;17(4):387-399.
Ginter K, Ahsan DM, Bizjak M, et al. Cryoglobulins, cryofibrinogens, and cold agglutinins in cold urticaria: literature review, retrospective patient analysis, and observational study in 49 patients. Front Immunol. 2021;12:675451. https://doi.org/10.3389/fimmu.2021.675451.
Jain SV, Mullins RJ. Cold urticaria: a 20-year follow-up study. J Eur Acad Dermatol Venereol. 2016;30(12):2066-2071.
Fernando SL. Cold-induced anaphylaxis. J Pediatr. 2009;154(1):148.
Sampson HA, Mendelson L, Rosen JP. Fatal and near-fatal anaphylactic reactions to food in children and adolescents. N Engl J Med. 1992;327(6):380-384.
Pumphrey RS. Lessons for management of anaphylaxis from a study of fatal reactions. Clin Exp Allergy. 2000;30(8):1144-1150.
Bock SA, Munoz-Furlong A, Sampson HA. Further fatalities caused by anaphylactic reactions to food, 2001-2006. J Allergy Clin Immunol. 2007;119(4):1016-1018.
Paulino M, Costa C, Neto M, Pedro E. Cold urticaria. Characterizing the population from an urticaria outpatient clinic. Actas Dermosifiliogr (Engl Ed). 2021;112(8):740-746.
Kulthanan K, Tuchinda P, Chularojanamontri L, Kiratiwongwan R. Cold urticaria: clinical features and natural course in a tropical country. Allergy Asthma Immunol Res. 2019;11(4):538-547.
Yee CSK, El Khoury K, Albuhairi S, Broyles A, Schneider L, Rachid R. Acquired cold-induced urticaria in pediatric patients: a 22-year experience in a tertiary care center (1996-2017). J Allergy Clin Immunol Pract. 2019;7(3):1024-1031 e1023.
Stepaniuk P, Vostretsova K, Kanani A. Review of cold-induced urticaria characteristics, diagnosis and management in a Western Canadian allergy practice. Allergy Asthma Clin Immunol. 2018;14:85.
Deza G, Brasileiro A, Bertolin-Colilla M, Curto-Barredo L, Pujol RM, Gimenez-Arnau AM. Acquired cold urticaria: clinical features, particular phenotypes, and disease course in a tertiary care center cohort. J Am Acad Dermatol. 2016;75(5):918-924 e912.
Siebenhaar F, Degener F, Zuberbier T, Martus P, Maurer M. High-dose desloratadine decreases wheal volume and improves cold provocation thresholds compared with standard-dose treatment in patients with acquired cold urticaria: a randomized, placebo-controlled, crossover study. J Allergy Clin Immunol. 2009;123(3):672-679.
Katsarou-Katsari A, Makris M, Lagogianni E, Gregoriou S, Theoharides T, Kalogeromitros D. Clinical features and natural history of acquired cold urticaria in a tertiary referral hospital: a 10-year prospective study. J Eur Acad Dermatol Venereol. 2008;22(12):1405-1411.
Alangari AA, Twarog FJ, Shih MC, Schneider LC. Clinical features and anaphylaxis in children with cold urticaria. Pediatrics. 2004;113(4):e313-e317.
Mathelier-Fusade P, Aissaoui M, Bakhos D, Chabane MH, Leynadier F. Clinical predictive factors of severity in cold urticaria. Arch Dermatol. 1998;134(1):106-107.
Wanderer AA, Grandel KE, Wasserman SI, Farr RS. Clinical characteristics of cold-induced systemic reactions in acquired cold urticaria syndromes: recommendations for prevention of this complication and a proposal for a diagnostic classification of cold urticaria. J Allergy Clin Immunol. 1986;78(3):417-423.
Doeglas HM, Rijnten WJ, Schroder FP, Schirm J. Cold urticaria and virus infections: a clinical and serological study in 39 patients. Br J Dermatol. 1986;114(3):311-318.
Neittaanmaki H. Cold urticaria. Clinical findings in 220 patients. J Am Acad Dermatol. 1985;13(4):636-644.
Gernez Y, Sicherer SH, Wang J. Variability in diagnosis and management of acquired cold-induced urticaria. J Allergy Clin Immunol Pract. 2018;6(4):1396-1399.
Maurer M, Metz M, Bindslev-Jensen C, et al. Definition, aims, and implementation of GA(2) LEN Urticaria Centers of Reference and Excellence. Allergy. 2016;71(8):1210-1218.
Sampson HA, Munoz-Furlong A, Campbell RL, et al. Second symposium on the definition and management of anaphylaxis: summary report-Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium. J Allergy Clin Immunol. 2006;117(2):391-397.https://pubmed.ncbi.nlm.nih.gov/16461139/.
Mlynek A, Magerl M, Siebenhaar F, et al. Results and relevance of critical temperature threshold testing in patients with acquired cold urticaria. Br J Dermatol. 2010;162(1):198-200.
Abajian M, Młynek A, Maurer M. Physical Urticaria. Curr Allergy Asthma Rep. 2012;12(4):281-287.
Buss YL, Sticherling M. Cold urticaria; disease course and outcome-an investigation of 85 patients before and after therapy. Br J Dermatol. 2005;153(2):440-441.
Black AK, Sibbald RG, Greaves MW. Cold urticaria treated by induction of tolerance. Lancet. 1979;2(8149):964.
Hochstadter EF, Ben-Shoshan M. Cold-induced urticaria: challenges in diagnosis and management. BMJ Case Rep. 2013;2013:bcr2013010441.
Krause K, Zuberbier T, Maurer M. Modern approaches to the diagnosis and treatment of cold contact urticaria. Curr Allergy Asthma Rep. 2010;10(4):243-249.
Abajian M, Curto-Barredo L, Krause K, et al. Rupatadine 20 mg and 40 mg are effective in reducing the symptoms of chronic cold urticaria. Acta Derm Venereol. 2016;96(1):56-59.
Kingery FA. Cold Urticaria. JAMA. 1965;192:107.
Stoevesandt J, Sturm GJ, Bonadonna P, Oude Elberink JNG, Trautmann A. Risk factors and indicators of severe systemic insect sting reactions. Allergy. 2020;75(3):535-545.
Kosnik M, Korosec P. Venom immunotherapy: clinical efficacy, safety and contraindications. Expert Rev Clin Immunol. 2015;11(8):877-884.
Selb J, Rijavec M, Erzen R, et al. D816V screening identifies clonal mast cell disease in patients with Hymenoptera allergy regularly missed using baseline tryptase levels alone. J Allergy Clin Immunol. 2021;148(2):621-626 e627. https://pubmed.ncbi.nlm.nih.gov/33753098/.
Moller A, Henning M, Zuberbier T, Czarnetzki-Henz BM. Epidemiologie und Klinik der Kälteurtikaria [Epidemiology and clinical aspects of cold urticaria]. Hautarzt. 1996;47(7):510-514. https://pubmed.ncbi.nlm.nih.gov/8926165/.
-
Contributed Indexing:
-
Keywords: COLD-CE; adrenaline autoinjector; cold urticaria; risk factors; systemic reactions
-
Entry Date(s):
-
Date Created: 20211204 Date Completed: 20220701 Latest Revision: 20220830
-
Update Code:
-
20240105
-
DOI:
-
10.1111/all.15194
-
PMID:
-
34862605
-
Background: Cold urticaria (ColdU), that is, the occurrence of wheals or angioedema in response to cold exposure, is classified into typical and atypical forms. The diagnosis of typical ColdU relies on whealing in response to local cold stimulation testing (CST). It can also manifest with cold-induced anaphylaxis (ColdA). We aimed to determine risk factors for ColdA in typical ColdU.
Methods: An international, cross-sectional study COLD-CE was carried out at 32 urticaria centers of reference and excellence (UCAREs). Detailed history was taken and CST with an ice cube and/or TempTest ® performed. ColdA was defined as an acute cold-induced involvement of the skin and/or visible mucosal tissue and at least one of: cardiovascular manifestations, difficulty breathing, or gastrointestinal symptoms.
Results: Of 551 ColdU patients, 75% (n = 412) had a positive CST and ColdA occurred in 37% (n = 151) of the latter. Cold-induced generalized wheals, angioedema, acral swelling, oropharyngeal/laryngeal symptoms, and itch of earlobes were identified as signs/symptoms of severe disease. ColdA was most commonly provoked by complete cold water immersion and ColdA caused by cold air was more common in countries with a warmer climate. Ten percent (n = 40) of typical ColdU patients had a concomitant chronic spontaneous urticaria (CSU). They had a lower frequency of ColdA than those without CSU (4% vs. 39%, p = .003). We identified the following risk factors for cardiovascular manifestations: previous systemic reaction to a Hymenoptera sting, angioedema, oropharyngeal/laryngeal symptoms, and itchy earlobes.
Conclusion: ColdA is common in typical ColdU. High-risk patients require education about their condition and how to use an adrenaline autoinjector.
(© 2021 The Authors. Allergy published by European Academy of Allergy and Clinical Immunology and John Wiley & Sons Ltd.)
