Peritoneal Dialysis-Related Peritonitis: Rate, Clinical Outcomes and Patient Survival.

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Abstrakt

Tytuł:: Peritoneal Dialysis-Related Peritonitis: Rate, Clinical Outcomes and Patient Survival.
Autorzy:: Dzekova-Vidimliski P; University Hospital of Nephrology, Skopje, R. North Macedonia.
Nikolov IG; University Hospital of Nephrology, Skopje, R. North Macedonia.
Gjorgjievski N; University Hospital of Nephrology, Skopje, R. North Macedonia.
Selim G; University Hospital of Nephrology, Skopje, R. North Macedonia.
Trajceska L; University Hospital of Nephrology, Skopje, R. North Macedonia.
Stojanoska A; University Hospital of Nephrology, Skopje, R. North Macedonia.
Rambabova-Bushljetik I; University Hospital of Nephrology, Skopje, R. North Macedonia.
Simeonov R; Acibadem Sistina Hospital, Skopje, R. North Macedonia.
Stojkovski L; Acibadem Sistina Hospital, Skopje, R. North Macedonia.
Źródło:: Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki) [Pril (Makedon Akad Nauk Umet Odd Med Nauki)] 2021 Dec 30; Vol. 42 (3), pp. 47-55. Date of Electronic Publication: 2021 Dec 30.
Typ publikacji:: Journal Article
Język:: English
Imprint Name(s):: Original Publication: Skopje : Makedonska akademija na naukite i umetnostite, [2013]-
MeSH Terms:: Kidney Failure, Chronic*/diagnosis
Kidney Failure, Chronic*/therapy
Peritoneal Dialysis*/adverse effects
Peritonitis*/epidemiology
Peritonitis*/etiology
Humans ; Renal Dialysis ; Retrospective Studies ; Survival Rate
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Contributed Indexing:: Keywords: bacteria; infection; peritoneal dialysis; peritonitis; survival
Entry Date(s):: Date Created: 20220115 Date Completed: 20220118 Latest Revision: 20220125
Update Code:: 20240105
DOI:: 10.2478/prilozi-2021-0034
PMID:: 35032377
: Czasopismo naukowe

Pełny tekst

Peritoneal dialysis-related peritonitis remains the major complication and primary challenge to the long-term success of peritoneal dialysis (PD). The study aimed to analyze the peritonitis rate, the cause, the outcomes, and the association of peritonitis with the survival of patients on peritoneal dialysis. Patient data were collected retrospectively from medical charts. A total of 96 patients received peritoneal dialysis in the PD center from 1 January 1999 to 31 December 2018. Episodes of peritonitis (n=159) were registered in 54 (56.3%) patients. The study population was divided into two groups, a group of patients (n=54) who experienced peritonitis and a group of patients free of peritonitis (n=42). The peritonitis rate was 0.47 episodes per patient year. The majority of causative microorganisms were gram-positive bacteria (53.5%). Outcomes of the episodes of peritonitis were resolved infection in 84.9% of episodes, catheter removal in 11.3% of episodes, and death in 3.8% of the episodes of peritonitis. A Kaplan-Meier analysis and log-rank test revealed that the group with peritonitis tended to survive significantly longer than the peritonitis-free group. A 67% reduction rate in the risk of patient mortality was observed for the peritonitis group compared with the peritonitis-free group (hazard ratio: 0.33, 95% CI 0.19-0.57, P=0.000). The prevention and management of PD-related infections, resulted in their worldwide reduction, supporting the use of PD as a first-line dialysis modality.
(© 2021 Ioannis Chrysikos, published by Sciendo.)

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