Effects of resistance training, palm pollen grain extracts, and testosterone injection on luteinizing hormone receptors, claudin-1, cingulin, and zonula occludens in the prostate tissues of adult male rats.

Tytuł:: Effects of resistance training, palm pollen grain extracts, and testosterone injection on luteinizing hormone receptors, claudin-1, cingulin, and zonula occludens in the prostate tissues of adult male rats.
Autorzy:: Nazarian A; Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
Azarbayjani MA; Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
Atashak S; Department of Exercise Physiology, Mahabad Branch, Islamic Azad University, Mahabad, Iran.
Peeri M; Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
Źródło:: Andrologia [Andrologia] 2022 Jun; Vol. 54 (5), pp. e14394. Date of Electronic Publication: 2022 Feb 28.
Typ publikacji:: Journal Article
Język:: English
Imprint Name(s):: Publication: : Berlin : Blackwell Pub.
Original Publication: Berlin, Grosse
MeSH Terms:: Phoeniceae*
Physical Conditioning, Animal*
Pollen*
Prostate*/metabolism
Animals ; Claudin-1 ; Male ; Membrane Proteins ; Microfilament Proteins ; Plant Extracts/pharmacology ; Rats ; Receptors, LH ; Testosterone ; Tight Junctions
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Grant Information:: Islamic Azad University Central Tehran Branch
Contributed Indexing:: Keywords: claudin-1; palm pollen; prostate; resistance exercise; tight junction
Substance Nomenclature:: 0 (Claudin-1)
0 (Membrane Proteins)
0 (Microfilament Proteins)
0 (Plant Extracts)
0 (Receptors, LH)
3XMK78S47O (Testosterone)
Entry Date(s):: Date Created: 20220228 Date Completed: 20220520 Latest Revision: 20220531
Update Code:: 20240104
DOI:: 10.1111/and.14394
PMID:: 35226967
: Czasopismo naukowe

Pełny tekst

The present study aimed to investigate the effects of resistance training, Phoenix dactylifera extract, and testosterone enanthate injection on luteinizing hormone receptor, claudin-1, cingulin, and zonula occludens in the prostate tissues of adult rats. 30 male rats were divided into six groups: (1) control, (2) resistance training, (3) Phoenix dactylifera extract, (4) testosterone enanthate, (5) resistance training+Phoenix dactylifera extract, and (6) resistance training + testosterone enanthate. After completing the treatments and resistance training, all rats were sacrificed via anaesthesia. The results showed that resistance training, Phoenix dactylifera, and testosterone enanthate significantly increased the luteinizing hormone receptor, claudin-1, cingulin, and zonula occludens gene expression levels in the prostate. The resistance training treatment, along with Phoenix dactylifera + testosterone enanthate, exerted synergic effects on the prostate luteinizing hormone receptor levels and claudin-1 gene expression. In conclusion, Phoenix dactylifera, as a natural compound with fewer side effects than testosterone injection, can be used to enhance athletic performance. Besides, considering the potential benefits of Phoenix dactylifera, it can be considered in the treatment of testosterone deficiency; however, further research is needed.
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