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Tytuł:
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A two-photon fluorogenic probe based on a coumarin schiff base for formaldehyde detection in living cells.
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Autorzy:
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Zhang Y; College of Chemistry and Chemical Engineering, Yangtze Normal University, Fuling, Chongqing 408100, PR China. Electronic address: .
Qiu X; College of Chemistry and Chemical Engineering, Yangtze Normal University, Fuling, Chongqing 408100, PR China.
Sun L; College of Chemistry and Chemical Engineering, Yangtze Normal University, Fuling, Chongqing 408100, PR China.
Yan Q; College of Chemistry and Chemical Engineering, Yangtze Normal University, Fuling, Chongqing 408100, PR China.
Luck RL; Department of Chemistry, Michigan Technological University, Houghton, MI 49931, United States. Electronic address: .
Liu H; Department of Chemistry, Michigan Technological University, Houghton, MI 49931, United States. Electronic address: .
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Źródło:
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Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2022 Jun 05; Vol. 274, pp. 121074. Date of Electronic Publication: 2022 Feb 28.
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Typ publikacji:
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Journal Article
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Język:
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English
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Imprint Name(s):
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Publication: : Amsterdam : Elsevier
Original Publication: [Kidlington, Oxford, U.K. ; Tarrytown, NY] : Pergamon, c1994-
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MeSH Terms:
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Fluorescent Dyes*
Schiff Bases*
Coumarins ; Formaldehyde ; HeLa Cells ; Humans
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Contributed Indexing:
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Keywords: Coumarin fluorophore; Fluorogenic probe; Formaldehyde; Living cell; Two-photon excitation microscopy
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Substance Nomenclature:
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0 (Coumarins)
0 (Fluorescent Dyes)
0 (Schiff Bases)
1HG84L3525 (Formaldehyde)
A4VZ22K1WT (coumarin)
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Entry Date(s):
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Date Created: 20220308 Date Completed: 20220411 Latest Revision: 20220411
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Update Code:
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20240104
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DOI:
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10.1016/j.saa.2022.121074
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PMID:
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35257990
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A novel two-photon fluorogenic probe has been developed to detect formaldehyde with fast response, low cytotoxicity, and excellent selectivity. This probe exhibits a strong turn-on fluorescence response to formaldehyde under excitation at 370 nm and has been successfully applied to detect formaldehyde in living cells. Theoretical calculations at the B3LYP/6-31 + G(d,p), APFD/6-311++G, and APFD/6-311 + G(2d,p) levels of theory for the absorption and emission wavelengths of the probes were in agreement with those obtained experimentally.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2022 Elsevier B.V. All rights reserved.)
