LINC00662 Promotes Proliferation and Invasion and Inhibits Apoptosis of Glioma Cells Through miR-483-3p/SOX3 Axis.

Szczegóły
Abstrakt

Tytuł:: LINC00662 Promotes Proliferation and Invasion and Inhibits Apoptosis of Glioma Cells Through miR-483-3p/SOX3 Axis.
Autorzy:: Yuan L; Department of Neurosurgery, the Affiliated Sixth People's Hospital, Shanghai Jiaotong University, No. 600 Yishan Road, Shanghai, 200233, China.
Zhang P; Department of Neurosurgery, the Affiliated Sixth People's Hospital, Shanghai Jiaotong University, No. 600 Yishan Road, Shanghai, 200233, China.
Lu Y; Department of Neurosurgery, the Affiliated Sixth People's Hospital, Shanghai Jiaotong University, No. 600 Yishan Road, Shanghai, 200233, China.
Zhang A; Department of Neurosurgery, the Affiliated Sixth People's Hospital, Shanghai Jiaotong University, No. 600 Yishan Road, Shanghai, 200233, China.
Chen X; Department of Neurosurgery, the Affiliated Sixth People's Hospital, Shanghai Jiaotong University, No. 600 Yishan Road, Shanghai, 200233, China. .
Źródło:: Applied biochemistry and biotechnology [Appl Biochem Biotechnol] 2022 Jul; Vol. 194 (7), pp. 2857-2871. Date of Electronic Publication: 2022 Mar 11.
Typ publikacji:: Journal Article
Język:: English
Imprint Name(s):: Original Publication: Clifton, N.J. : Humana Press, c1981-
MeSH Terms:: Glioma*/genetics
Glioma*/metabolism
MicroRNAs*/genetics
MicroRNAs*/metabolism
RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
Apoptosis/genetics ; Carcinogenesis/genetics ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Gene Expression Regulation, Neoplastic ; Humans ; SOXB1 Transcription Factors/genetics
References:: Ostrom, Q. T., Bauchet, L., Davis, F. G., et al. (2014). The epidemiology of glioma in adults: A “state of the science” review. Neuro-Oncology, 16(7), 896–913. (PMID: 10.1093/neuonc/nou087)
Milano, M. T., Johnson, M. D., Sul, J., et al. (2010). Primary spinal cord glioma: A surveillance, epidemiology, and end results database study. Journal of Neuro-Oncology, 98(1), 83–92. (PMID: 10.1007/s11060-009-0054-7)
Lorenzi, L., Avila Cobos, F., Decock, A., et al. (2019). Long noncoding RNA expression profiling in cancer: Challenges and opportunities. Genes, Chromosomes & Cancer, 58(4), 191–199. (PMID: 10.1002/gcc.22709)
Liu, D., Zou, Z., Li, G., Pan, P., & Liang, G. (2020). Long noncoding RNA NEAT1 suppresses proliferation and promotes apoptosis of glioma cells via downregulating miR-92b. Cancer Control, 27(1), 1073274819897977. (PMID: 319333776961147)
Shi, J., Zhang, Y., Qin, B., Wang, Y., & Zhu, X. (2019). Long non-coding RNA LINC00174 promotes glycolysis and tumor progression by regulating miR-152-3p/SLC2A1 axis in glioma. Journal of Experimental & Clinical Cancer Research : CR, 38(1), 395–395. (PMID: 10.1186/s13046-019-1390-x)
Xiong, Z., Wang, L., Wang, Q., & Yuan, Y. (2018). LncRNA MALAT1/miR-129 axis promotes glioma tumorigenesis by targeting SOX2. Journal of Cellular and Molecular Medicine, 22(8), 3929–3940. (PMID: 10.1111/jcmm.13667)
Gong, W., Su, Y., Liu, Y., Sun, P., & Wang, X. (2018). Long non-coding RNA Linc00662 promotes cell invasion and contributes to cancer stem cell-like phenotypes in lung cancer cells. J Biochem, 164(6), 461–469. (PMID: 10.1093/jb/mvy078)
Wang, H., Yu, M., Hu, W., et al. (2019). Linc00662 promotes tumorigenesis and progression by regulating miR-497-5p/AVL9 axis in colorectal cancer. Frontiers in Genetics, 10, 1385. (PMID: 10.3389/fgene.2019.01385)
Li, N., Zhang, L. Y., Qiao, Y. H., & Song, R. J. (2019). Long noncoding RNA LINC00662 functions as miRNA sponge to promote the prostate cancer tumorigenesis through targeting miR-34a. European Review for Medical and Pharmacological Sciences, 23(9), 3688–3698. (PMID: 31114993)
Xu, D., Chen, Y., Yuan, C., Zhang, S., & Peng, W. (2019). Long non-coding RNA LINC00662 promotes proliferation and migration in oral squamous cell carcinoma. OncoTargets and Therapy, 12, 647–656. (PMID: 10.2147/OTT.S188691)
Denzler, R., Agarwal, V., Stefano, J., Bartel, D. P., & Stoffel, M. (2014). Assessing the ceRNA hypothesis with quantitative measurements of miRNA and target abundance. Molecular Cell, 54(5), 766–776. (PMID: 10.1016/j.molcel.2014.03.045)
Lu, W., Zhang, H., Niu, Y., et al. (2017). Long non-coding RNA linc00673 regulated non-small cell lung cancer proliferation, migration, invasion and epithelial mesenchymal transition by sponging miR-150-5p. Molecular Cancer, 16(1), 118. (PMID: 10.1186/s12943-017-0685-9)
C. Luo, Z. Quan, B. Zhong, et al., lncRNA XIST promotes glioma proliferation and metastasis through miR-133a/SOX4, Experimental and therapeutic medicine 2020; 19(3): 1641-1648.
M.-N. Menbari, K. Rahimi, A. Ahmadi, et al., miR-483-3p suppresses the proliferation and progression of human triple negative breast cancer cells by targeting the HDAC8>oncogene, Journal of cellular physiology 2020; 235(3): 2631-2642.
Pepe, F., Visone, R., & Veronese, A. (2018). The Glucose-regulated miR-483-3p influences key signaling pathways in cancer. Cancers (Basel), 10(6), 181. (PMID: 10.3390/cancers10060181)
Guo, Y., Yin, J., Tang, M., & Yu, X. (2018). Downregulation of SOX3 leads to the inhibition of the proliferation, migration and invasion of osteosarcoma cells. Int J Oncol, 52(4), 1277–1284. (PMID: 29484385)
Acloque, H., Ocaña, O. H., Matheu, A., et al. (2011). Reciprocal repression between Sox3 and snail transcription factors defines embryonic territories at gastrulation. Developmental Cell, 21(3), 546–558. (PMID: 10.1016/j.devcel.2011.07.005)
Shen, J., Zhai, J., Wu, X., Xie, G., & Shen, L. (2020). Serum proteome profiling reveals SOX3 as a candidate prognostic marker for gastric cancer. Journal of Cellular and Molecular Medicine, 24(12), 6750–6761. (PMID: 10.1111/jcmm.15326)
Marjanovic Vicentic, J., Drakulic, D., Garcia, I., et al. (2019). SOX3 can promote the malignant behavior of glioblastoma cells. Cell Oncol (Dordr), 42(1), 41–54. (PMID: 10.1007/s13402-018-0405-5)
Zhang, Y., Jiang, X., Wu, Z., et al. (2020). Long Noncoding RNA LINC00467 promotes glioma progression through inhibiting P53 expression via binding to DNMT1. Journal of Cancer, 11(10), 2935–2944. (PMID: 10.7150/jca.41942)
Peng, W. X., Koirala, P., & Mo, Y. Y. (2017). LncRNA-mediated regulation of cell signaling in cancer. Oncogene, 36(41), 5661–5667. (PMID: 10.1038/onc.2017.184)
Geng, Y., Wu, Y., Xu, C., Li, T., & Zhang, L. (2020). Long non-coding RNA LINC00662 regulated proliferation and migration by targeting miR-34a-5p/LMAN2L axis in glioma. Onco Targets and Therapy, 13, 10161–10172. (PMID: 10.2147/OTT.S272616)
Wu, J., Guo, X., & Xu, D. (2020). H Zhang, LINC00662 sponges miR-107 accelerating the invasiveness and proliferation of glioma cells. Journal of Cancer, 11(19), 5700–5712. (PMID: 10.7150/jca.46381)
Guo, J., Yang, Z., Zhou, H., et al. (2020). Upregulation of DKK3 by miR-483-3p plays an important role in the chemoprevention of colorectal cancer mediated by black raspberry anthocyanins. Molecular Carcinogenesis, 59(2), 168–178. (PMID: 10.1002/mc.23138)
W. Wu, N. Wei, G. Shao, et al., circZNF609 promotes the proliferation and migration of gastric cancer by sponging miR-483-3p and regulating CDK6, OncoTargets and therapy 2019; 12: 8197-8205.
Yasukawa, K., Liew, L. C., Hagiwara, K., et al. (2020). MicroRNA-493-5p-mediated repression of the MYCN oncogene inhibits hepatic cancer cell growth and invasion. Cancer Science, 111(3), 869–880. (PMID: 10.1111/cas.14292)
K. Wu, J. Wang, J. He, Q. Chen, L. Yang, miR-483-3p promotes proliferation and migration of neuroblastoma cells by targeting PUMA, International journal of clinical and experimental pathology 2018; 11(2): 490-501.
Li, S., Zheng, K., Pei, Y., Wang, W., & Zhang, X. (2019). Long noncoding RNA NR2F1-AS1 enhances the malignant properties of osteosarcoma by increasing forkhead box A1 expression via sponging of microRNA-483-3p. Aging, 11(23), 11609–11623. (PMID: 10.18632/aging.102563)
J.M. Adams, S. Cory, The Bcl-2 protein family: Arbiters of cell survival, Science (New York, N.Y.) 1998; 281(5381): 1322-6.
Lefebvre, V., Dumitriu, B., Penzo-Méndez, A., Han, Y., & Pallavi, B. (2007). Control of cell fate and differentiation by Sry-related high-mobility-group box (Sox) transcription factors. The International Journal of Biochemistry & Cell Biology, 39(12), 2195–2214. (PMID: 10.1016/j.biocel.2007.05.019)
Im, C.-N., Yun, H. H., Yoo, H. J., Park, M.-J., & Lee, J.-H. (2015). Enhancement of SOX-2 expression and ROS accumulation by culture of A172 glioblastoma cells under non-adherent culture conditions. Oncology Reports, 34(2), 920–928. (PMID: 10.3892/or.2015.4021)
Garros-Regulez, L., Aldaz, P., Arrizabalaga, O., et al. (2016). mTOR inhibition decreases SOX2-SOX9 mediated glioma stem cell activity and temozolomide resistance. Expert Opin Ther Targets, 20(4), 393–405. (PMID: 10.1517/14728222.2016.1151002)
Zhao, T., Yang, H., Tian, Y., et al. (2016). SOX7 is associated with the suppression of human glioma by HMG-box dependent regulation of Wnt/β-catenin signaling. Cancer Letters, 375(1), 100–107. (PMID: 10.1016/j.canlet.2016.02.044)
Titulaer, M. J., Klooster, R., Potman, M., et al. (2009). SOX antibodies in small-cell lung cancer and Lambert-Eaton myasthenic syndrome: Frequency and relation with survival. Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology, 27(26), 4260–4267. (PMID: 10.1200/JCO.2008.20.6169)
Contributed Indexing:: Keywords: Glioma; LINC00662; SOX3; miR-483-3p
Substance Nomenclature:: 0 (MIRN483 microRNA, human)
0 (MicroRNAs)
0 (RNA, Long Noncoding)
0 (SOX3 protein, human)
0 (SOXB1 Transcription Factors)
Entry Date(s):: Date Created: 20220311 Date Completed: 20220621 Latest Revision: 20220622
Update Code:: 20240105
DOI:: 10.1007/s12010-022-03855-2
PMID:: 35275355
: Czasopismo naukowe

Full Text Finder

LINC00662 plays a prominent role in the carcinogenesis and progression of diverse cancers. However, its biological functions in glioma are still unclear. LINC00662 expression in glioma tissue samples and cell lines was examined by quantitative real-time polymerase chain reaction. The correlation between LINC00662 expression and the clinical characteristics of 50 patients with glioma was analyzed. LINC00662 knockdown and overexpression cell lines were constructed, and the effects of LINC00662 on the proliferation, invasion, and apoptosis of glioma cells were evaluated by cell counting kit-8, 5-ethynyl-2'-deoxyuridine, Transwell, and flow cytometry assays, respectively. Besides, the relationships among LINC00662, miR-483-3p, and sex-determining region Y-box 3 (SOX3) were assessed by dual-luciferase reporter assay and RNA immunoprecipitation assay. Western blot was used to detect the regulatory effects of LINC00662 and miR-483-3p on SOX3 expression in glioma cells. LINC00662 expression level was elevated in glioma tissues and cell lines compared to that in normal tissues and cell lines. LINC00662 high expression was associated with the adverse prognosis of patients with glioma. Knockdown of LINC00662 repressed the proliferation and invasion of glioma cells, and promoted apoptosis. Additionally, it was revealed that LINC00662 acted as the molecular sponge of miR-483-3p, and SOX3 was verified as a direct target of miR-483-3p. The inhibition of miR-483-3p expression and SOX3 overexpression reversed the biological effects of LINC00662 knockdown on glioma cells. This study reports the key regulatory role of LINC00662/miR-483-3p/SOX3 axis in the tumorigenesis and progression of glioma, bringing novel insights into the underlying mechanisms of glioma.
(© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)

Informacja