Emergence of Candida auris in intensive care units in Algeria.

Tytuł:: Emergence of Candida auris in intensive care units in Algeria.
Autorzy:: Zerrouki H; Aix-Marseille Université, IRD, APHM, MEPHI, Marseille, France.; IHU-Méditerranée Infection, Marseille, France.; Laboratoire de Microbiologie Appliquée à l'Agroalimentaire, au Biomédical et à l'Environnement, Université de Tlemcen, Tlemcen, Algeria.
Ibrahim A; Aix-Marseille Université, IRD, APHM, MEPHI, Marseille, France.; IHU-Méditerranée Infection, Marseille, France.
Rebiahi SA; Laboratoire de Microbiologie Appliquée à l'Agroalimentaire, au Biomédical et à l'Environnement, Université de Tlemcen, Tlemcen, Algeria.
Elhabiri Y; Laboratoire de Microbiologie Appliquée à l'Agroalimentaire, au Biomédical et à l'Environnement, Université de Tlemcen, Tlemcen, Algeria.
Benhaddouche DE; Service d'anesthésie et de réanimation, Centre Hospitalo-Universitaire Tlemcen, Tlemcen, Algeria.
de Groot T; Department of Medical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.; Centre of Expertise in Mycology, Radboudumc/Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.
Meis JF; Department of Medical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.; Centre of Expertise in Mycology, Radboudumc/Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.
Rolain JM; Aix-Marseille Université, IRD, APHM, MEPHI, Marseille, France.; IHU-Méditerranée Infection, Marseille, France.
Bittar F; Aix-Marseille Université, IRD, APHM, MEPHI, Marseille, France.; IHU-Méditerranée Infection, Marseille, France.
Źródło:: Mycoses [Mycoses] 2022 Jul; Vol. 65 (7), pp. 753-759. Date of Electronic Publication: 2022 May 31.
Typ publikacji:: Journal Article
Język:: English
Imprint Name(s):: Original Publication: Berlin : Grosse Verlag, [1988?-
MeSH Terms:: Antifungal Agents*/pharmacology
Antifungal Agents*/therapeutic use
Candidiasis*/diagnosis
Candidiasis*/drug therapy
Candidiasis*/epidemiology
Algeria/epidemiology ; Candida/genetics ; Candida auris ; Humans ; Intensive Care Units ; Microbial Sensitivity Tests
References:: J Hosp Infect. 2017 Dec;97(4):363-370. (PMID: 28939316)
Clin Infect Dis. 2017 Jan 15;64(2):134-140. (PMID: 27988485)
Am J Transplant. 2017 Jan;17(1):296-299. (PMID: 28029734)
Mycoses. 2022 Feb;65(2):134-139. (PMID: 34780087)
Lancet Infect Dis. 2018 Dec;18(12):1377-1384. (PMID: 30293877)
Antimicrob Resist Infect Control. 2020 Apr 7;9(1):50. (PMID: 32264966)
PLoS Pathog. 2017 May 18;13(5):e1006290. (PMID: 28542486)
Microbiol Immunol. 2009 Jan;53(1):41-4. (PMID: 19161556)
Int J Infect Dis. 2019 Aug;85:182-187. (PMID: 31185293)
J Clin Microbiol. 2015 Jun;53(6):1823-30. (PMID: 25809970)
J Clin Microbiol. 2017 Oct;55(10):2996-3005. (PMID: 28747370)
J Mycol Med. 2021 Sep;31(3):101139. (PMID: 33965885)
Med Mycol. 2020 Jan 1;58(1):124-127. (PMID: 30874806)
Emerg Infect Dis. 2019 Jan;25(1):192-194. (PMID: 30561310)
Med Mycol. 2013 Oct;51(7):713-20. (PMID: 23611419)
PLoS Pathog. 2020 Oct 22;16(10):e1008921. (PMID: 33091071)
Eur J Clin Microbiol Infect Dis. 2021 Jul;40(7):1547-1551. (PMID: 33515096)
Microbiologyopen. 2018 Aug;7(4):e00578. (PMID: 29345117)
J Mycol Med. 2018 Sep;28(3):568-573. (PMID: 30030072)
Antimicrob Agents Chemother. 2017 Jul 25;61(8):. (PMID: 28584152)
Emerg Infect Dis. 2019 Sep;25(9):1763-1765. (PMID: 31223105)
J Fungi (Basel). 2021 May 29;7(6):. (PMID: 34072592)
Nat Med. 2021 Aug;27(8):1401-1409. (PMID: 34155414)
PLoS Pathog. 2019 Apr 8;15(4):e1007638. (PMID: 30958866)
J Antimicrob Chemother. 2017 Jun 1;72(6):1794-1801. (PMID: 28333181)
Mycoses. 2022 Jul;65(7):753-759. (PMID: 35546294)
mBio. 2020 Jan 7;11(1):. (PMID: 31911492)
Am J Infect Control. 2021 Jun;49(6):804-807. (PMID: 33485922)
Emerg Infect Dis. 2018 Nov;24(11):2036-2040. (PMID: 30334713)
MMWR Morb Mortal Wkly Rep. 2017 May 19;66(19):514-515. (PMID: 28520710)
Emerg Microbes Infect. 2021 Dec;10(1):1300-1308. (PMID: 34176429)
Med Mycol. 2016 Mar;54(3):256-65. (PMID: 26613703)
J Fungi (Basel). 2020 Nov 21;6(4):. (PMID: 33233388)
BMC Infect Dis. 2020 Nov 11;20(1):827. (PMID: 33176724)
Front Microbiol. 2019 Aug 20;10:1918. (PMID: 31481947)
Clin Microbiol Rev. 2017 Nov 15;31(1):. (PMID: 29142078)
J Glob Antimicrob Resist. 2020 Jun;21:181-185. (PMID: 31655136)
mBio. 2020 Apr 28;11(2):. (PMID: 32345637)
mSphere. 2019 Jul 31;4(4):. (PMID: 31366705)
Mycopathologia. 2019 Jun;184(3):353-365. (PMID: 31209693)
Expert Rev Anti Infect Ther. 2020 Jun;18(6):551-562. (PMID: 32237924)
J Fungi (Basel). 2020 Sep 22;6(3):. (PMID: 32971857)
Grant Information:: Agence Nationale de la Recherche
Contributed Indexing:: Keywords: Candida auris; Algeria; ICU; clades (I-IV); emergence
Substance Nomenclature:: 0 (Antifungal Agents)
Entry Date(s):: Date Created: 20220513 Date Completed: 20220621 Latest Revision: 20220731
Update Code:: 20240105
PubMed Central ID:: PMC9328195
DOI:: 10.1111/myc.13470
PMID:: 35546294
: Czasopismo naukowe

Pełny tekst

Background: Currently, Candida auris is among the most serious emerging pathogens that can be associated with nosocomial infections and outbreaks in intensive care units. Clinicians must be able to identify and manage it quickly.
Objective: Here, we report for the first time in Algeria seven cases of C. auris infection or colonisation.
Methods and Results: The strains were isolated from clinical sites including bronchial aspirates (n = 4), wound swabs (n = 1), urine sample (n = 1) and peritoneal fluid (n = 1), in patients admitted to the intensive care unit. Candida auris was identified both by MALDI-TOF and by sequencing the ITS region and the D1/D2 domain. Antifungal susceptibility testing was performed using the E-test method. Non-wildtype susceptibility was observed for five strains against fluconazole, itraconazole, voriconazole and caspofungin. Genotyping showed the presence of four clades (I-IV) in one hospital.
Conclusions: Appropriate antifungal treatments with rapid and accurate microbial identification are the cornerstone for the management and control of C. auris infections.
(© 2022 The Authors. Mycoses published by Wiley-VCH GmbH.)

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