The network structure of cognitive deficits in first episode psychosis patients.

Szczegóły
Abstrakt

Tytuł:: The network structure of cognitive deficits in first episode psychosis patients.
Autorzy:: Sánchez-Torres AM; Department of Psychiatry, Hospital Universitario de Navarra, Pamplona, Spain; Instituto de Investigación Sanitaria de Navarra (IdiSNa), Pamplona, Spain.
Peralta V; Instituto de Investigación Sanitaria de Navarra (IdiSNa), Pamplona, Spain; Mental Health Department, Servicio Navarro de Salud-Osasunbidea, Pamplona, Spain.
Gil-Berrozpe GJ; Department of Psychiatry, Hospital Universitario de Navarra, Pamplona, Spain; Instituto de Investigación Sanitaria de Navarra (IdiSNa), Pamplona, Spain.
Mezquida G; Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Barcelona Clinic Schizophrenia Unit, Hospital Clinic of Barcelona, Neuroscience Institute, Spain; Department of Medicine, Institut de Neurociències, Universitat de Barcelona, Spain; August Pi I Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.
Ribeiro M; Department of Psychiatry, Hospital Universitario de Navarra, Pamplona, Spain; Instituto de Investigación Sanitaria de Navarra (IdiSNa), Pamplona, Spain.
Molina-García M; Department of Child and Adolescent Psychiatry, Hospital General Universitario Gregorio Marañón, Spain; Instituto de Investigación Sanitaria Gregorio Marañón, Spain; School of Psychology, Complutense University, Madrid, Spain.
Amoretti S; Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Barcelona Clinic Schizophrenia Unit, Hospital Clinic of Barcelona, Neuroscience Institute, Spain; Department of Medicine, Institut de Neurociències, Universitat de Barcelona, Spain; August Pi I Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.
Lobo A; Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Department of Medicine and Psychiatry, Zaragoza University, Instituto de Investigación Sanitaria Aragón (IIS Aragón), Zaragoza, Spain.
González-Pinto A; Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Department of Psychiatry, Araba University Hospital, Bioaraba Research Institute, Department of Neurociences, University of the Basque Country, Vitoria, Spain.
Merchán-Naranjo J; Department of Child and Adolescent Psychiatry, Hospital General Universitario Gregorio Marañón, Spain; Instituto de Investigación Sanitaria Gregorio Marañón, Spain; School of Psychology, Complutense University, Madrid, Spain.
Corripio I; Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Psychiatry Department, Institut d'Investigació Biomèdica-Sant Pau (IIB-SANT PAU), Hospital de la Santa Creu i Sant Pau, Spain; Universitat Autònoma de Barcelona (UAB), Barcelona, Spain; Hospital Clinic, Institute of Neuroscience, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain.
Vieta E; Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Hospital Clinic, Institute of Neuroscience, University of Barcelona, IDIBAPS, Barcelona, Spain.
de la Serna E; Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Department of Child and Adolescent Psychiatry and Psychology, Institut Clinic de Neurociències, Hospital Clínic Universitari, Barcelona 2017SGR881, Spain.
Bergé D; Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Hospital del Mar Medical Research Institute (IMIM), Autonomous University of Barcelona (UAB), Barcelona, Spain.
Bernardo M; Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Barcelona Clinic Schizophrenia Unit, Hospital Clinic of Barcelona, Neuroscience Institute, Spain; Department of Medicine, Institut de Neurociències, Universitat de Barcelona, Spain; August Pi I Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.
Cuesta MJ; Department of Psychiatry, Hospital Universitario de Navarra, Pamplona, Spain; Instituto de Investigación Sanitaria de Navarra (IdiSNa), Pamplona, Spain. Electronic address: .
Corporate Authors:: PEPs Group
Źródło:: Schizophrenia research [Schizophr Res] 2022 Jun; Vol. 244, pp. 46-54. Date of Electronic Publication: 2022 May 17.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
Język:: English
Imprint Name(s):: Original Publication: Amsterdam : Elsevier Science Publisher B. V., c1988-
MeSH Terms:: Cognition Disorders*/etiology
Cognition Disorders*/psychology
Psychotic Disorders*/complications
Psychotic Disorders*/psychology
Cognition ; Humans ; Memory, Short-Term ; Neuropsychological Tests
Contributed Indexing:: Investigator: B Cabrera, Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Barcelona Clinic Schizophrenia Unit, Hospital Clinic of Barcelona, Neuroscience Institute, Spain; Department of Medicine, Institut de Neurociències, Universitat de Barcelona, Spain; August Pi I Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; M Pons, Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Barcelona Clinic Schizophrenia Unit, Hospital Clinic of Barcelona, Neuroscience Institute, Spain; Department of Medicine, Institut de Neurociències, Universitat de Barcelona, Spain; August Pi I Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; R Abregú-Crespo, Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Department of Child and Adolescent Psychiatry, Hospital General Universitario Gregorio Marañón, Spain; Instituto de Investigación Sanitaria Gregorio Marañón, Spain; School of Psychology, Complutense University, Madrid, Spain.; M Rapado-Castro, Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Department of Child and Adolescent Psychiatry, Hospital General Universitario Gregorio Marañón, Spain; Instituto de Investigación Sanitaria Gregorio Marañón, Spain; School of Psychology, Complutense University, Madrid, Spain.; A Alonso-Solís, Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Psychiatry Department, Institut d'Investigació Biomèdica-Sant Pau (IIB-SANT PAU), Hospital de la Santa Creu i Sant Pau, Spain; Universitat Autònoma de Barcelona (UAB), Barcelona, Spain; Hospital Clinic, Institute of Neuroscience, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain.; E Grasa, Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Psychiatry Department, Institut d'Investigació Biomèdica-Sant Pau (IIB-SANT PAU), Hospital de la Santa Creu i Sant Pau, Spain; Universitat Autònoma de Barcelona (UAB), Barcelona, Spain; Hospital Clinic, Institute of Neuroscience, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain.; I González-Ortega, Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Department of Psychiatry, Araba University Hospital, Bioaraba Research Institute, Department of Neurociences, University of the Basque Country, Vitoria, Spain.; S Alberich, Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Department of Psychiatry, Araba University Hospital, Bioaraba Research Institute, Department of Neurociences, University of the Basque Country, Vitoria, Spain.; C de la Cámara, Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Department of Medicine and Psychiatry, Zaragoza University, Instituto de Investigación Sanitaria Aragón (IIS Aragón), Zaragoza, Spain.; P Saz, Department of Medicine and Psychiatry, Zaragoza University, Instituto de Investigación Sanitaria Aragón (IIS Aragón), Zaragoza, Spain.; EJ Aguilar, Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; INCLIVA, School of Medicine, University of Valencia, Valencia, Spain.; MJ Escartí, Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; INCLIVA, School of Medicine, University of Valencia, Valencia, Spain; Department of Psychiatry, Hospital Clinic, Valencia, Spain.; L Martínez, Hospital del Mar Medical Research Institute (IMIM), Autonomous University of Barcelona (UAB), Barcelona, Spain.; A Toll, Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Hospital del Mar Medical Research Institute (IMIM), Autonomous University of Barcelona (UAB), Barcelona, Spain.; P Gavin, Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Hospital Clinic, Institute of Neuroscience, University of Barcelona, IDIBAPS, Barcelona, Spain.; C Varo, Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Hospital Clinic, Institute of Neuroscience, University of Barcelona, IDIBAPS, Barcelona, Spain.; I Baeza, Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Department of Child and Adolescent Psychiatry and Psychology, Institut Clinic de Neurociències, Hospital Clínic Universitari, Barcelona 2017SGR881, Spain.; O Puig, Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Department of Child and Adolescent Psychiatry and Psychology, Institut Clinic de Neurociències, Hospital Clínic Universitari, Barcelona 2017SGR881, Spain.; F Contreras, Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Bellvitge Biomedical Research Institute IDIBELL, Department of Psychiatry-Bellvitge University Hospital, Hospitalet de Llobregat-Barcelona, Spain; University of Barcelona, Department of Clinical Sciences, School of Medicine, Barcelona, Spain.; C Saiz-Masvidal, Bellvitge Biomedical Research Institute IDIBELL, Department of Psychiatry-Bellvitge University Hospital, Hospitalet de Llobregat-Barcelona, Spain; University of Barcelona, Department of Clinical Sciences, School of Medicine, Barcelona, Spain.; LG Álvarez, Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Department of Psychiatry, Universidad de Oviedo, Oviedo, Spain; Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain; Instituto Universitario de Neurociencias del Principado de Asturias (INEUROPA), Oviedo, Spain; Department of Psychology, Universidad de Oviedo, Oviedo, Spain.; MTB Bascarán, Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain; Servicio de Salud del Principado de Asturias (SESPA), Oviedo, Spain; Instituto Universitario de Neurociencias del Principado de Asturias (INEUROPA), Oviedo, Spain; Department of Psychology, Universidad de Oviedo, Oviedo, Spain.; MG Fraile, Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Department of Psychiatry, Araba University Hospital, Bioaraba Research Institute, Department of Neurociences, University of the Basque Country, Vitoria, Spain.; AZ Rabadán, Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; University of the Basque Country (UPV/EHU), Department of Neurosciences, BioCruces Health Research Institute, Vizcaya, Spain.; L Sanchez-Pastor, Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Madrid, Spain.; R Rodriguez-Jimenez, Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Madrid, Spain; CogPsy Group, Universidad Complutense de Madrid (UCM), Madrid, Spain.; J Usall, Parc Sanitari Sant Joan de Déu, Sant Boi de Llobregat, Child and Adolescent Psychiatry and Psychology Department, Hospital Sant Joan de Déu of Barcelona, Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain.; A Butjosa, Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Parc Sanitari Sant Joan de Déu, Sant Boi de Llobregat, Child and Adolescent Psychiatry and Psychology Department, Hospital Sant Joan de Déu of Barcelona, Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain.; S Sarró, Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; FIDMAG Germanes Hospitalàries Research Foundation, Barcelona, Spain; School of Medicine, Universitat Internacional de Catalunya, Barcelona, Spain.; R Landín-Romero, Neuroscience Research Australia, Sydney, NSW, Australia; School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia; ARC Centre of Excellence in Cognition and its Disorders, Sydney, NSW, Australia.; Á Ibáñez, Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Department of Psychiatry, Hospital Universitario Ramon y Cajal, Universidad de Alcala, Instituto Ramon y Cajal de Investigacion Sanitaria (IRyCIS), Madrid, Spain.; L Moreno-Izco, Department of Psychiatry, Complejo Hospitalario de Navarra, Pamplona, Spain; Instituto de Investigación Sanitaria de Navarra (IdiSNa), Pamplona, Spain.; V Balanzá-Martínez, Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, Spain; Teaching Unit of Psychiatry, Department of Medicine, University of Valencia, Valencia, Spain.
Keywords: Attention; Cognition; First-episode psychosis; Network analysis; Verbal memory; Working memory
Entry Date(s):: Date Created: 20220520 Date Completed: 20220621 Latest Revision: 20220726
Update Code:: 20240105
DOI:: 10.1016/j.schres.2022.05.005
PMID:: 35594732
: Czasopismo naukowe

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Network analysis is an important conceptual and analytical approach in mental health research. However, few studies have used network analysis to examine the structure of cognitive performance in psychotic disorders. We examined the network structure of the cognitive scores of a sample of 207 first-episode psychosis (FEP) patients and 188 healthy controls. Participants were assessed using a battery of 10 neuropsychological tests. Fourteen cognitive scores encompassing six cognitive domains and premorbid IQ were selected to perform the network analysis. Many similarities were found in the network structure of FEP patients and healthy controls. Verbal memory, attention, working memory and executive function nodes were the most central nodes in the network. Nodes in both groups corresponding to the same tests tended to be strongly connected. Verbal memory, attention, working memory and executive function were central dimensions in the cognitive network of FEP patients and controls. These results suggest that the interplay between these core dimensions is essential for demands to solve complex tasks, and these interactions may guide the aims of cognitive rehabilitation. Network analysis of cognitive dimensions might have therapeutic implications that deserve further research.
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