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Tytuł:
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Sustained improvements in EQ-5D utility scores and self-rated health status in patients with ankylosing spondylitis after spa treatment including low-dose radon - an analysis of prospective radon indication registry data.
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Autorzy:
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van der Zee-Neuen A; Center for Physiology, Pathophysiology and Biophysics, Institute for Physiology and Pathophysiology, Salzburg, Austria. .; Gastein Research Institute, Paracelsus Medical University, Strubergasse 22, 5020, Salzburg, Austria. .; Institute of Nursing Science and Practice, Paracelsus Medical University, Salzburg, Austria. .; Center for Public Health and Healthcare Research, Paracelsus Medical University, Salzburg, Austria. .
Strobl V; Center for Physiology, Pathophysiology and Biophysics, Institute for Physiology and Pathophysiology, Salzburg, Austria.; Gastein Research Institute, Paracelsus Medical University, Strubergasse 22, 5020, Salzburg, Austria.; Ludwig Boltzmann Institute for Arthritis and Rehabilitation, Salzburg, Austria.
Dobias H; Center for Physiology, Pathophysiology and Biophysics, Institute for Physiology and Pathophysiology, Salzburg, Austria.; Gastein Research Institute, Paracelsus Medical University, Strubergasse 22, 5020, Salzburg, Austria.; Ludwig Boltzmann Institute for Arthritis and Rehabilitation, Salzburg, Austria.
Fuchs J; Center for Physiology, Pathophysiology and Biophysics, Institute for Physiology and Pathophysiology, Salzburg, Austria.; Gastein Research Institute, Paracelsus Medical University, Strubergasse 22, 5020, Salzburg, Austria.; Ludwig Boltzmann Institute for Arthritis and Rehabilitation, Salzburg, Austria.
Untner J; Gastein Healing Gallery, Bad Gastein, Austria.
Foisner W; Cure and Rehabilitation Center, Bad Hofgastein, Austria.
Knapp M; Stiftung Kurtherme Badehospiz, Bad Gastein, Austria.
Edtinger S; Baerenhof Health Care & Rehabilitation Center, Bad Gastein, Austria.; Department of Physical Medicine and Rehabilitation, Kardinal Schwarzenberg Klinikum, Schwarzach Im Pongau, Austria.
Offenbächer M; Gastein Healing Gallery, Bad Gastein, Austria.
Ritter M; Center for Physiology, Pathophysiology and Biophysics, Institute for Physiology and Pathophysiology, Salzburg, Austria.; Gastein Research Institute, Paracelsus Medical University, Strubergasse 22, 5020, Salzburg, Austria.; Ludwig Boltzmann Institute for Arthritis and Rehabilitation, Salzburg, Austria.; Center for Physiology, Pathophysiology and Biophysics, Institute for Physiology, Pathophysiology and Biophysics, Nuremberg, Germany.; Kathmandu University School of Medical Sciences, Dhulikhel, Nepal.
Hölzl B; Gastein Healing Gallery, Bad Gastein, Austria.; Department of Internal Medicine, Landesklinik St. Veit Im Pongau, SALK, Paracelsus Medical University, Salzburg, Austria.
Gaisberger M; Center for Physiology, Pathophysiology and Biophysics, Institute for Physiology and Pathophysiology, Salzburg, Austria. .; Gastein Research Institute, Paracelsus Medical University, Strubergasse 22, 5020, Salzburg, Austria. .; Ludwig Boltzmann Institute for Arthritis and Rehabilitation, Salzburg, Austria. .
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Źródło:
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BMC musculoskeletal disorders [BMC Musculoskelet Disord] 2022 Aug 03; Vol. 23 (1), pp. 743. Date of Electronic Publication: 2022 Aug 03.
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Typ publikacji:
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Journal Article
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Język:
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English
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Imprint Name(s):
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Original Publication: London : BioMed Central, [2000-
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MeSH Terms:
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Radon*/therapeutic use
Spondylitis, Ankylosing*/therapy
Female ; Health Status ; Humans ; Male ; Middle Aged ; Prospective Studies ; Quality of Life ; Registries ; Surveys and Questionnaires
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References:
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Contributed Indexing:
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Keywords: Ankylosing spondylitis; Quality of life; Radon; Spa therapy
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Substance Nomenclature:
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Q74S4N8N1G (Radon)
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Entry Date(s):
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Date Created: 20220803 Date Completed: 20220805 Latest Revision: 20220807
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Update Code:
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20240104
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PubMed Central ID:
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PMC9347130
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DOI:
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10.1186/s12891-022-05691-1
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PMID:
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35922780
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Background: Patients with ankylosing spondylitis (AS) have significantly lower quality of life (QoL) than the general population. Holistic interventions addressing QoL comprise spa- or balneotherapy including radon. These interventions have shown to be beneficial in reducing pain and improving QoL in AS-patients. We explored the association of spa-therapy including low-dose radon with QoL in AS-patients over an extended time period.
Methods: Registry data collected for the "Radon indication registry" in the Austrian Gastein valley comprising data on QoL (EuroQol EQ-5D) directly before the treatment (baseline), directly(t1), 3 (t2); 6(t3) and 9(t4) months after the treatment, age, sex and body mass index (BMI) were analysed. Linear regression models explored the association of measurement time with 1) EQ-5D-5L utilities and 2) EuroQol visual analogue scale (VAS) score. Alterations of 0.05 (utilities) and 5.00 (VAS) were considered clinically relevant.
Results: Two-hundred-ninety-one AS-patients were included in the analyses. Forty-four percent (n = 128) were women, the mean age was 52 (SD 10) and the average BMI was 26 (SD 4). Utilities (t1: 0.09 [0.07;0.11]; t2: 0.08 [0.06; 0.10]; t3: 0.06 [0.05;0.09]; t4: 0.04 [0.02;0.06]) and VAS (t1: 11.68 [9.38; 13.97]; t2: 12.20 [9.78; 14.61]; t3: 9.70 [7.24; 12.17]; t4: 6.11 [3.57; 8.65]) were significantly higher at all timepoints compared to baseline. Improvements were clinically relevant at all timepoints in case of the VAS and until 6 months after treatment for the utilities.
Conclusion: AS-patients who received spa therapy including radon show significantly and clinically relevant improvements in Qol until 6-9 months after treatment.
(© 2022. The Author(s).)
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