The percentage and clinical correlates of alexithymia in stable patients with schizophrenia.

Tytuł:: The percentage and clinical correlates of alexithymia in stable patients with schizophrenia.
Autorzy:: Yi Y; Department of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, 36 Mingxin Rd, Liwan District, Guangzhou, 510370, China.
Huang Y; Department of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, 36 Mingxin Rd, Liwan District, Guangzhou, 510370, China.
Jiang R; Department of Psychiatry, Qingdao Mental Health Center, Qingdao, China.
Chen Q; Department of Psychiatry, The Brain Hospital of Guangxi Zhuang Autonomous Region, Guangxi, China.
Yang M; Department of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, 36 Mingxin Rd, Liwan District, Guangzhou, 510370, China.
Li H; Department of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, 36 Mingxin Rd, Liwan District, Guangzhou, 510370, China.
Feng Y; Department of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, 36 Mingxin Rd, Liwan District, Guangzhou, 510370, China.
Feng S; Department of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, 36 Mingxin Rd, Liwan District, Guangzhou, 510370, China.
Zhou S; Department of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, 36 Mingxin Rd, Liwan District, Guangzhou, 510370, China.
Zhang L; Department of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, 36 Mingxin Rd, Liwan District, Guangzhou, 510370, China.
Ning Y; Department of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, 36 Mingxin Rd, Liwan District, Guangzhou, 510370, China.; Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China.
Li Z; Department of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, 36 Mingxin Rd, Liwan District, Guangzhou, 510370, China. .
Wu F; Department of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, 36 Mingxin Rd, Liwan District, Guangzhou, 510370, China. .; Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China. .
Źródło:: European archives of psychiatry and clinical neuroscience [Eur Arch Psychiatry Clin Neurosci] 2023 Apr; Vol. 273 (3), pp. 679-686. Date of Electronic Publication: 2022 Oct 14.
Typ publikacji:: Journal Article
Język:: English
Imprint Name(s):: Original Publication: Berlin ; New York : Springer International, c1990-
MeSH Terms:: Affective Symptoms*/epidemiology
Affective Symptoms*/etiology
Schizophrenia*/complications
Schizophrenia*/epidemiology
Schizophrenia*/diagnosis
Humans ; Psychopathology ; East Asian People
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Grant Information:: 2019B030316001 Science and Technology Program of Guizhou Province
Contributed Indexing:: Keywords: Alexithymia; Depressive symptoms; Negative symptoms; Schizophrenia
Entry Date(s):: Date Created: 20221014 Date Completed: 20230412 Latest Revision: 20230413
Update Code:: 20240104
PubMed Central ID:: PMC10085932
DOI:: 10.1007/s00406-022-01492-8
PMID:: 36239818
: Czasopismo naukowe

Pełny tekst

Alexithymia is a common, but less-recognized affective deficit in patients with schizophrenia. To date, no definitive conclusions have been drawn about the relationship between alexithymia and the clinical symptoms or their clinical correlates, particularly in stable patients with schizophrenia. The purpose of this study was to investigate the link between alexithymia and psychopathological symptoms, as well as any associated correlates, in stable patients with schizophrenia. A total of 435 Chinese patients with schizophrenia were recruited. The Positive and Negative Symptoms Scale (PANSS) was used to evaluate each patient's psychopathological symptoms. The Toronto Alexithymia Scale (TAS-20) was used to measure alexithymia. The percentage of alexithymia was 35.2% in stable patients with schizophrenia. Compared to non-alexithymia patients, patients with alexithymia had higher PANSS total scores, negative subscores, depressive subscores, and cognitive subscores (all p < 0.05). Multivariate regression analysis revealed that the following variables were positively associated with TAS-20 total scores: PANSS negative subscores (β = 0.274, t = 3.198, p = 0.001) and PANSS depressive subscores (β = 0.366, t = 2.500, p = 0.013). Education years (β = - 0.453, t = - 2.824, p = 0.005) was negatively associated with TAS-20 total scores. Our results suggest that the percentage of alexithymia was relatively higher in stable patients with schizophrenia. Education levels, negative symptoms, and depressive symptoms were independently associated with alexithymia in this specific population.
(© 2022. The Author(s).)

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