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Tytuł:
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Is suboptimal effort an issue? A systematic review on neuropsychological performance validity in major depressive disorder.
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Autorzy:
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Legemaat AM; Department of Psychiatry Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam Neuroscience & Amsterdam Public Health, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands.
Haagedoorn MAS; Department of Geriatric Psychiatry, Mental Health Care North-Holland North, Maelsonstraat 1, 1624 NP Hoorn, the Netherlands.
Burger H; Department of General Practice and Elderly Care Medicine, University Medical Center Groningen, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, the Netherlands.
Denys D; Department of Psychiatry Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam Neuroscience & Amsterdam Public Health, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands.
Bockting CL; Department of Psychiatry Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam Neuroscience & Amsterdam Public Health, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands; Centre for Urban Mental Health, University of Amsterdam, Oude Turfmarkt 147, 1012 GC Amsterdam, the Netherlands.
Geurtsen GJ; Department of Medical Psychology Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam Neuroscience & Amsterdam Public Health, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands. Electronic address: .
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Źródło:
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Journal of affective disorders [J Affect Disord] 2023 Feb 15; Vol. 323, pp. 731-740. Date of Electronic Publication: 2022 Dec 14.
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Typ publikacji:
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Systematic Review; Journal Article; Review
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Język:
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English
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Imprint Name(s):
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Original Publication: Amsterdam, Elsevier/North-Holland Biomedical Press.
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MeSH Terms:
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Depressive Disorder, Major*/diagnosis
Depressive Disorder, Major*/psychology
Cognition Disorders*/psychology
Cognitive Dysfunction*/diagnosis
Cognitive Dysfunction*/etiology
Adult ; Humans ; Cognition ; Neuropsychological Tests
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Contributed Indexing:
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Keywords: Cognitive impairment; Depression; Major depressive disorder; Neuropsychological assessment; Performance validity; Symptom validity
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Entry Date(s):
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Date Created: 20221217 Date Completed: 20230112 Latest Revision: 20230317
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Update Code:
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20240105
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DOI:
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10.1016/j.jad.2022.12.043
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PMID:
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36528136
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Background: In Major Depressive Disorder (MDD), emotion- and motivation related symptoms may affect effort during neuropsychological testing. Performance Validity Tests (PVT's) are therefore essential, but are rarely mentioned in research on cognitive functioning in MDD. We aimed to assess the proportion of MDD patients with demonstrated valid performance and determine cognitive functioning in patients with valid performance. This is the first systematic review on neuropsychological performance validity in MDD.
Methods: Databases PubMed, PsycINFO, Embase, and Cochrane Library were searched for studies reporting on PVT results of adult MDD patients. We meta-analyzed the proportion of MDD patients with PVT scores indicative of valid performance.
Results: Seven studies with a total of 409 MDD patients fulfilled inclusion criteria. Six studies reported the exact proportion of patients with PVT scores indicative of valid performance, which ranged from 60 to 100 % with a proportion estimate of 94 %. Four studies reported on cognitive functioning in MDD patients with valid performance. Two out of these studies found memory impairment in a minority of MDD patients and two out of these studies found no cognitive impairment.
Limitations: Small number of studies and small sample sizes.
Conclusions: A surprisingly small number of studies reported on PVT in MDD. About 94 % of MDD patients in studies using PVT's had valid neuropsychological test performance. Concessive information regarding cognitive functioning in MDD patients with valid performance was lacking. Neuropsychological performance validity should be taken into account since this may alter conclusions regarding cognitive functioning.
Competing Interests: Conflict of interest We have no conflicts of interest to declare.
(Copyright © 2022 The Authors. Published by Elsevier B.V. All rights reserved.)
