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Tytuł pozycji:

Stakeholder views on informed consent models for future use of biological samples in Malawi and South Africa.

Tytuł:
Stakeholder views on informed consent models for future use of biological samples in Malawi and South Africa.
Autorzy:
Masiye F; Malawi University of Science and Technology, Ndata Farm, Thyolo, Malawi. .; Centre for Medical Ethics and Law, Stellenbosch University, Cape Town, South Africa. .
Jaoko W; Centre for Medical Ethics and Law, Stellenbosch University, Cape Town, South Africa.; University of Nairobi, Nairobi, Kenya.
Rennie S; Centre for Medical Ethics and Law, Stellenbosch University, Cape Town, South Africa.; University of North Carolina, Chapel Hill, North Carolina, USA.
Źródło:
BMC medical ethics [BMC Med Ethics] 2023 Jan 19; Vol. 24 (1), pp. 4. Date of Electronic Publication: 2023 Jan 19.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
Język:
English
Imprint Name(s):
Original Publication: London : BioMed Central, [2000-
MeSH Terms:
Research Subjects*
Biomedical Research*
Humans ; South Africa ; Malawi ; Informed Consent ; Qualitative Research
References:
BMC Med Ethics. 2014 Jan 22;15:4. (PMID: 24447822)
BMC Med Ethics. 2012 Oct 16;13:27. (PMID: 23072321)
BMC Med Ethics. 2017 Feb 2;18(1):8. (PMID: 28153006)
Lancet Oncol. 2006 Mar;7(3):266-9. (PMID: 16510336)
BMC Med Ethics. 2015 Dec 02;16(1):83. (PMID: 26626016)
BMC Med Ethics. 2016 Oct 10;17(1):57. (PMID: 27724893)
Science. 2014 Jun 20;344(6190):1346-8. (PMID: 24948725)
Eur J Hum Genet. 2015 Feb;23(2):141-6. (PMID: 24801761)
Br J Cancer. 2009 Jan 13;100(1):8-12. (PMID: 19034276)
Am J Bioeth. 2015;15(9):34-42. (PMID: 26305750)
J Med Ethics. 2010 Sep;36(9):539-47. (PMID: 20663757)
Soc Sci Med. 2005 Sep;61(6):1211-22. (PMID: 15970232)
BMC Med Ethics. 2019 Oct 15;20(1):71. (PMID: 31615491)
Camb Q Healthc Ethics. 2012 Jan;21(1):40-50. (PMID: 22152457)
Grant Information:
D43 TW01511-01 United States TW FIC NIH HHS; U01 HG008222 United States HG NHGRI NIH HHS
Contributed Indexing:
Keywords: Broad consent; Focus group discussion and in-depth interview; Informed consent; Specific consent; Tiered consent
Entry Date(s):
Date Created: 20230119 Date Completed: 20230123 Latest Revision: 20230207
Update Code:
20240104
PubMed Central ID:
PMC9854061
DOI:
10.1186/s12910-023-00882-4
PMID:
36658544
Czasopismo naukowe
Background: Current advances in biomedical research have introduced new ethical challenges in obtaining informed consent in low and middle-income settings. For example, there are controversies about the use of broad consent in the collection of biological samples for use in future biomedical research. However, few studies have explored preferred informed consent models for future use of biological samples in Malawi and South Africa. Therefore, we conducted an empirical study to understand preferred consent models among key stakeholders in biomedical studies that involve collection of biological samples in Malawi and South Africa. The main objective of the study was to explore views of key stakeholders on current policies on informed consent in Malawi and South Africa.
Methods: This was a qualitative study involving in-depth interviews and focus group discussions. Thirty-four in-depth interviews and 6 focus group discussions were conducted with REC members, Funders, Policymakers, CAB members and Research Participants in Malawi and South Africa to gather their views on models of informed consent. The study was conducted in Cape Town, South Africa, and Blantyre and Lilongwe in Malawi.
Results: Most key stakeholders preferred broad consent and tiered consent to specific consent. Some participants expressed a strong preference for specific consent to other models of informed consent in biomedical research. Few participants did not have any preference for a consent model, opting for any consent model which provides adequate information about the proposed research and what their national consent regulations require. Finally, very few participants preferred blanket consent to other informed consent models.
Conclusions: This study aimed to help fill the gap in the scientific literature on key stakeholder views on consent models for future use of biological samples in Malawi and South Africa. The findings of the study have provided some evidence that may support policies on permissible consent models for future use of biological samples in sub-Saharan Africa considering the differences in informed consent regulations and guidelines. Finally, the findings can inform ongoing discussions on permissible consent models to be used for future use of biological samples.
(© 2023. The Author(s).)

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