Epidemiology of GII.4 and GII.2 norovirus outbreaks in closed and semi-closed institutions in 2017 and 2018.

Tytuł:: Epidemiology of GII.4 and GII.2 norovirus outbreaks in closed and semi-closed institutions in 2017 and 2018.
Autorzy:: Cornejo-Sánchez T; Laboratori de Microbiologia, Hospital Universitari Vall d'Hebrón, Barcelona, Spain.
Soldevila N; CIBER Epidemiología y Salut Pública (CIBERSP), Madrid, Spain. .; Departament de Medicina, Universitat de Barcelona, Barcelona, Spain. .
Coronas L; Departament de Medicina, Universitat de Barcelona, Barcelona, Spain.; Agència de Salut Pública de Catalunya, Barcelona, Spain.
Alsedà M; Agència de Salut Pública de Catalunya, Barcelona, Spain.
Godoy P; CIBER Epidemiología y Salut Pública (CIBERSP), Madrid, Spain.; Agència de Salut Pública de Catalunya, Barcelona, Spain.; Institut de Recerca Biomédica de Lleida, IRB Lleida, Lleida, Spain.
Razquín E; Agència de Salut Pública de Barcelona (ASPB), Barcelona, Spain.
Sabaté S; Agència de Salut Pública de Barcelona (ASPB), Barcelona, Spain.
Guix S; Departament de Genètica Microbiologia i Estadística, Grup de Virus Entèrics, Universitat de Barcelona, Barcelona, Spain.; Nutrition and Food Safety Research Institute (INSA·UB), Universitat de Barcelona, 08921, Santa Coloma de Gramenet, Spain.
Rodríguez Garrido V; Laboratori de Microbiologia, Hospital Universitari Vall d'Hebrón, Barcelona, Spain.
Bartolomé R; Laboratori de Microbiologia, Hospital Universitari Vall d'Hebrón, Barcelona, Spain.
Domínguez A; CIBER Epidemiología y Salut Pública (CIBERSP), Madrid, Spain.; Departament de Medicina, Universitat de Barcelona, Barcelona, Spain.
Corporate Authors:: Working Group for the Study of Outbreaks of Acute Gastroenteritis in Catalonia
Źródło:: Scientific reports [Sci Rep] 2023 Jan 30; Vol. 13 (1), pp. 1659. Date of Electronic Publication: 2023 Jan 30.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
Język:: English
Imprint Name(s):: Original Publication: London : Nature Publishing Group, copyright 2011-
MeSH Terms:: Norovirus*/genetics
Gastroenteritis*/epidemiology
Caliciviridae Infections*/epidemiology
Humans ; Adolescent ; Genotype ; Molecular Epidemiology ; Disease Outbreaks ; Phylogeny
References:: Epidemiol Infect. 2019 Jan;147:e207. (PMID: 31364544)
J Clin Virol. 2014 Jun;60(2):96-104. (PMID: 24746342)
PLoS One. 2017 Jun 29;12(6):e0179572. (PMID: 28662035)
J Gen Virol. 2019 Oct;100(10):1393-1406. (PMID: 31483239)
J Food Prot. 2013 Oct;76(10):1810-6. (PMID: 24112586)
Open Forum Infect Dis. 2017 Aug 03;4(3):ofx131. (PMID: 32455144)
Epidemiol Infect. 2003 Aug;131(1):737-44. (PMID: 12948374)
PLoS One. 2013 Oct 02;8(10):e75922. (PMID: 24098406)
Viruses. 2019 Apr 10;11(4):. (PMID: 30974898)
Adv Food Nutr Res. 2018;86:13-53. (PMID: 30077220)
PLoS Pathog. 2017 Jan 19;13(1):e1006136. (PMID: 28103318)
Viruses. 2019 Apr 11;11(4):. (PMID: 30979014)
Clin Infect Dis. 2020 Dec 3;71(9):2398-2404. (PMID: 31720684)
J Infect. 2017 Sep;75(3):216-224. (PMID: 28633888)
Viruses. 2019 Apr 29;11(5):. (PMID: 31035642)
Virus Evol. 2019 Nov 25;5(2):vez048. (PMID: 32161666)
BMC Infect Dis. 2019 Jan 25;19(1):87. (PMID: 30683063)
Lancet Infect Dis. 2018 May;18(5):545-553. (PMID: 29396001)
Euro Surveill. 2014 Jul 24;19(29):. (PMID: 25080141)
Clin Infect Dis. 2021 Oct 5;73(7):e1525-e1531. (PMID: 32667045)
Annu Rev Food Sci Technol. 2015;6:411-33. (PMID: 25884284)
Zhonghua Liu Xing Bing Xue Za Zhi. 2018 Sep 10;39(9):1210-1215. (PMID: 30293312)
Zhonghua Liu Xing Bing Xue Za Zhi. 2020 Mar 10;41(3):417-422. (PMID: 32294846)
Nat Rev Microbiol. 2016 Jul;14(7):421-33. (PMID: 27211790)
J Clin Virol. 2013 Mar;56(3):185-93. (PMID: 23218993)
J Clin Virol. 2016 May;78:111-9. (PMID: 27018574)
Sci Rep. 2018 Oct 15;8(1):15238. (PMID: 30323290)
Euro Surveill. 2017 Jan 26;22(4):. (PMID: 28181902)
Gut Pathog. 2019 May 24;11:26. (PMID: 31143245)
J Med Virol. 2019 Jun;91(6):1014-1021. (PMID: 30735247)
Contributed Indexing:: Investigator: J Álvarez; AI Belver; N Camps; S Minguell; M Carol; C Izquierdo; I Parrón; C Pérez; A Rovira; M Sabaté; MR Sala; RM Vileu; I Barrabeig; M Jané; A Martínez; N Torner; J de Benito; A Moreno-Martínez; C Rius; A de Andres; E Camprubí; M Cunillé; ML Forns; M de Simón
Entry Date(s):: Date Created: 20230130 Date Completed: 20230201 Latest Revision: 20230314
Update Code:: 20240105
PubMed Central ID:: PMC9886968
DOI:: 10.1038/s41598-023-28448-9
PMID:: 36717621
: Czasopismo naukowe

Pełny tekst

Norovirus infections are a leading cause of acute gastroenteritis outbreaks worldwide, with genotypes GII.2 and GII.4 being the most prevalent. The aim of this study was to compare the characteristics of GII.2 and GII.4 norovirus outbreaks reported in Catalonia in closed or semi-closed institutions in 2017 and 2018. The epidemiological and clinical characteristics of GII.2 and GII.4 outbreaks were compared using the chi-square test or Fisher's exact test for categorical variables and the Mann-Whitney U test for continuous variables. Odds ratios and their 95% confidence intervals were estimated. 61 outbreaks were reported: GII.4 was the causative agent in 12 outbreaks (30%) and GII.2 in 9 outbreaks (22.5%). GII.2 outbreaks were detected more frequently in schools or summer camps (66.7%) and GII.4 outbreaks in nursing homes (91.7%) (p = 0.01). Ninety-three people were affected in GII.2 outbreaks and 94 in GII.4 outbreaks. The median age was 15 years (range: 1-95 years) in GII.2 outbreaks and 86 years (range: 0-100 years) in GII.4 outbreaks (p < 0.001). Nausea, abdominal pain, and headache were observed more frequently in persons affected by GII.2 outbreaks (p < 0.05). Symptomatic cases presented a higher viral load suggestive of greater transmission capacity, although asymptomatic patients presented relevant loads indicative of transmission capacity.
(© 2023. The Author(s).)

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