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Tytuł:
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Risk prediction for advanced neoplasia using longitudinal adherence measures to fecal immunochemical test-based colorectal cancer screening programs.
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Autorzy:
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de Jonge L; Department of Public Health, Erasmus MC, University Medical Center, Rotterdam, the Netherlands. Electronic address: .
Riggi E; Epidemiology and Screening Unit - CPO, University Hospital Città della Salute e della Scienza, Turin, Italy.
van Duuren LA; Department of Public Health, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.
Toes-Zoutendijk E; Department of Public Health, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.
Campari C; Screening Unit, AUSL IRCCS Reggio Emilia, Reggio Emilia, Italy.
Sassatelli R; Gastroenterology and Digestive Endoscopy Unit, IRCCS Santa Maria Nuova, Reggio Emilia, Italy.
Arrigoni A; Diagnostic and Interventional Digestive Endoscopy, FPO-IRCCS Candiolo Cancer Institute, Turin, Italy.
Orione L; Screening organisation and evaluation Unit, ASL CN1, Cuneo, Italy.
Lansdorp-Vogelaar I; Department of Public Health, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.
Senore C; Epidemiology and Screening Unit - CPO, University Hospital Città della Salute e della Scienza, Turin, Italy.
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Źródło:
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Preventive medicine [Prev Med] 2023 May; Vol. 170, pp. 107488. Date of Electronic Publication: 2023 Mar 16.
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Typ publikacji:
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Journal Article
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Język:
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English
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Imprint Name(s):
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Original Publication: New York, Academic Press.
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MeSH Terms:
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Mass Screening*
Colorectal Neoplasms*/diagnosis
Humans ; Pilot Projects ; Early Detection of Cancer ; Occult Blood ; Colonoscopy
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Contributed Indexing:
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Keywords: Adherence; Colorectal cancer; Fecal immunochemical test; Longitudinal adherence measure; Risk prediction; Screening
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Entry Date(s):
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Date Created: 20230317 Date Completed: 20230414 Latest Revision: 20230417
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Update Code:
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20240105
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DOI:
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10.1016/j.ypmed.2023.107488
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PMID:
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36931473
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Background: Patterns of longitudinal adherence may predict advanced neoplasia (AN) detection in subsequent rounds of colorectal cancer (CRC) screening. However, after more than five rounds, it is important to obtain a simplified measure. The aim was to determine the best simplified measure of longitudinal adherence to predict AN detection in CRC screening.
Methods: Individuals with four invitations from a Dutch Fecal immunochemical testing (FIT-)based pilot study and two Italian FIT-based CRC screening programs were included. We calculated AN detection in the fourth round, stratified by prior adherence. Five simplified measures were compared to full information (permutations) using chi-squared goodness-of-fit: adherence previous invitation, consistency, frequency, frequency + adherence previous invitation, and proportion of invitations covered.
Results: AN detection in the fourth round was highly dependent on prior adherence behavior. For inconsistent adherence, detection in the fourth round was strongly dependent on frequency and time since last participation. The performance of the simplified measures to capture this variation differed considerably. 'Adherence previous invitation' scored worst in predicting AN detection. 'Frequency+adherence previous invitation' had lowest chi-squared goodness-of-fit.
Discussion: The simplified measure 'frequency+adherence previous invitation' is the best measure to reflect patterns of longitudinal adherence and could be used to emphasize to individuals the importance of CRC screening.
Competing Interests: Declaration of Competing Interest The authors declare no conflict of interests.
(Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.)
