[Effect of pancreatic DNAse on the nuclear DNA topology of Candida tropicalis yeasts].

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Abstrakt

Tytuł:: [Effect of pancreatic DNAse on the nuclear DNA topology of Candida tropicalis yeasts].
Autorzy:: Kupriianova FG
Davydova MN
Kuznetsova NN
Vinter VG
Transliterated Title:: Vliianie pankreaticheskoĭ DNKazy na topologiiu iadernoĭ DNK drozhzheĭ Candida tropicalis.
Źródło:: Nauchnye doklady vysshei shkoly. Biologicheskie nauki [Nauchnye Doki Vyss Shkoly Biol Nauki] 1986 (4), pp. 24-9.
Typ publikacji:: Comparative Study; Journal Article
Język:: Russian
Imprint Name(s):: Publication: Moskva : Biologicheskie Nauki
Original Publication: Moskva.
MeSH Terms:: Candida/*drug effects
Cell Nucleus/*drug effects
DNA, Fungal/*metabolism
Deoxyribonucleases/*pharmacology
Nucleic Acid Conformation/*drug effects
Pancreas/*enzymology
Animals ; Candida/metabolism ; Cell Division/drug effects ; Cell Nucleus/metabolism ; Centrifugation, Density Gradient ; DNA, Fungal/analysis ; DNA, Single-Stranded/metabolism ; DNA, Superhelical/metabolism ; Time Factors ; Ultracentrifugation
Substance Nomenclature:: 0 (DNA, Fungal)
0 (DNA, Single-Stranded)
0 (DNA, Superhelical)
EC 3.1.- (Deoxyribonucleases)
Entry Date(s):: Date Created: 19860101 Date Completed: 19860718 Latest Revision: 20201209
Update Code:: 20240104
PMID:: 3708027
: Czasopismo naukowe

It has been shown that pancreatic DNAase added to the nutritious medium caused the change in the nuclear DNA topology of asporogenic Candida tropicalis yeast. DNA conformative changes are due to the unwinding of supertwisted molecules as a result of single-strand ruptures formation which induce DNA synthesis acceleration, cell growth and division.

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