Correlated variability in primate superior colliculus depends on functional class.

Tytuł:: Correlated variability in primate superior colliculus depends on functional class.
Autorzy:: Katz LN; Laboratory of Sensorimotor Research, National Eye Institute, Bethesda, MD, 20892, USA. .
Yu G; Laboratory of Sensorimotor Research, National Eye Institute, Bethesda, MD, 20892, USA.
Herman JP; Department of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, 15219, USA.
Krauzlis RJ; Laboratory of Sensorimotor Research, National Eye Institute, Bethesda, MD, 20892, USA.
Źródło:: Communications biology [Commun Biol] 2023 May 18; Vol. 6 (1), pp. 540. Date of Electronic Publication: 2023 May 18.
Typ publikacji:: Journal Article; Research Support, N.I.H., Intramural
Język:: English
Imprint Name(s):: Original Publication: London, United Kingdom : Nature Publishing Group UK, [2018]-
MeSH Terms:: Superior Colliculi*/physiology
Neurons*/physiology
Animals ; Macaca mulatta ; Memory, Short-Term
References:: J Neurosci. 1998 May 15;18(10):3870-96. (PMID: 9570816)
Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11252-5. (PMID: 21690375)
J Neurophysiol. 1972 Jul;35(4):575-86. (PMID: 4624741)
Nat Commun. 2021 Jul 22;12(1):4473. (PMID: 34294703)
Trends Neurosci. 2017 Jun;40(6):328-346. (PMID: 28515011)
J Neurophysiol. 1997 Nov;78(5):2732-41. (PMID: 9356422)
Nat Neurosci. 2014 Dec;17(12):1661-3. (PMID: 25383900)
Nat Rev Neurosci. 2011 Aug 10;12(9):509-23. (PMID: 21829219)
Neuron. 2008 Oct 9;60(1):162-73. (PMID: 18940596)
Neuroscientist. 2004 Dec;10(6):553-65. (PMID: 15534040)
J Neurosci. 2016 Jun 8;36(23):6225-41. (PMID: 27277801)
Science. 2010 Jan 29;327(5965):584-7. (PMID: 20110506)
Neuron. 2009 Sep 24;63(6):879-88. (PMID: 19778515)
Nat Neurosci. 2014 Jun;17(6):858-65. (PMID: 24777419)
Nature. 1994 Jul 14;370(6485):140-3. (PMID: 8022482)
J Neurosci. 1998 Sep 15;18(18):7519-34. (PMID: 9736670)
J Neurophysiol. 2002 Oct;88(4):2019-34. (PMID: 12364525)
J Neurophysiol. 1997 Dec;78(6):3493-7. (PMID: 9405568)
J Neurosci. 1997 Nov 1;17(21):8566-79. (PMID: 9334428)
Prog Brain Res. 2006;151:321-78. (PMID: 16221594)
Nat Neurosci. 2011 Jun 27;14(7):811-9. (PMID: 21709677)
Nat Neurosci. 2018 Apr;21(4):598-606. (PMID: 29483663)
Nat Neurosci. 2014 Oct;17(10):1410-7. (PMID: 25195105)
Annu Rev Neurosci. 2016 Jul 8;39:237-56. (PMID: 27145916)
Nat Neurosci. 2009 Dec;12(12):1594-600. (PMID: 19915566)
Nat Rev Neurosci. 2006 May;7(5):358-66. (PMID: 16760916)
J Neurosci. 2015 Jan 7;35(1):170-8. (PMID: 25568112)
J Neurophysiol. 2016 Oct 1;116(4):1807-1820. (PMID: 27466133)
J Neurosci. 2007 Jan 10;27(2):261-4. (PMID: 17215384)
Nat Neurosci. 2010 Mar;13(3):369-78. (PMID: 20173745)
Neuron. 2014 Sep 17;83(6):1329-34. (PMID: 25233315)
Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):E6973-82. (PMID: 26621747)
Neuron. 2011 Aug 25;71(4):750-61. (PMID: 21867889)
Annu Rev Neurosci. 1980;3:189-226. (PMID: 6774653)
J Neurosci. 2008 Nov 26;28(48):12591-603. (PMID: 19036953)
Nat Neurosci. 2016 Mar;19(3):383-93. (PMID: 26906505)
J Neurosci. 2000 Jan 1;20(1):387-400. (PMID: 10627615)
Annu Rev Neurosci. 2013 Jul 8;36:165-82. (PMID: 23682659)
Exp Brain Res. 1988;70(1):216-20. (PMID: 3402565)
Neuron. 2018 Oct 24;100(2):463-475. (PMID: 30359609)
Curr Opin Neurol. 2018 Feb;31(1):59-65. (PMID: 29076880)
Annu Rev Vis Sci. 2017 Sep 15;3:197-226. (PMID: 28617660)
Phys Rev E Stat Nonlin Soft Matter Phys. 2001 Nov;64(5 Pt 1):051904. (PMID: 11735965)
J Neurophysiol. 1989 Feb;61(2):331-49. (PMID: 2918358)
J Neurophysiol. 2000 Apr;83(4):1979-2001. (PMID: 10758109)
J Neurosci. 2014 Dec 3;34(49):16408-16. (PMID: 25471578)
Neuron. 1995 Mar;14(3):477-85. (PMID: 7695894)
Nature. 2009 Feb 26;457(7233):1133-6. (PMID: 19151698)
Annu Rev Neurosci. 2012;35:463-83. (PMID: 22483043)
Science. 2018 Jan 26;359(6374):463-465. (PMID: 29371470)
Neuron. 2014 Apr 2;82(1):235-48. (PMID: 24698278)
Cognition. 2005 Jul;96(3):B79-88. (PMID: 15996557)
J Comput Neurosci. 2021 Aug;49(3):229-249. (PMID: 33161507)
Annu Rev Neurosci. 2011;34:205-31. (PMID: 21456962)
J Neurophysiol. 1995 Jun;73(6):2334-48. (PMID: 7666142)
Spat Vis. 1997;10(4):433-6. (PMID: 9176952)
Neuron. 2011 May 26;70(4):773-86. (PMID: 21609831)
J Neurosci. 2005 Apr 6;25(14):3661-73. (PMID: 15814797)
J Neurosci. 2001 Mar 1;21(5):1676-97. (PMID: 11222658)
J Neurophysiol. 1985 Mar;53(3):603-35. (PMID: 3981231)
J Neurosci. 2019 Jun 5;39(23):4511-4526. (PMID: 30914447)
J Neurosci. 1992 Dec;12(12):4745-65. (PMID: 1464765)
Curr Opin Neurobiol. 2016 Apr;37:126-132. (PMID: 26922005)
Nat Rev Neurosci. 2013 May;14(5):350-63. (PMID: 23595013)
Front Neuroinform. 2012 Jan 31;6:1. (PMID: 22319490)
Neuron. 2012 Nov 8;76(3):590-602. (PMID: 23141070)
Neural Comput. 1999 Jan 1;11(1):91-101. (PMID: 9950724)
Nature. 1992 Feb 6;355(6360):542-5. (PMID: 1741032)
J Neurophysiol. 2013 Feb;109(4):940-7. (PMID: 23197461)
Nat Commun. 2015 Sep 21;6:8378. (PMID: 26387804)
eNeuro. 2017 Apr 12;4(2):. (PMID: 28413825)
J Neurophysiol. 1972 Jul;35(4):542-59. (PMID: 4624739)
Grant Information:: ZIA EY000511 United States ImNIH Intramural NIH HHS
Molecular Sequence:: Dryad 10.5061/dryad.12jm63z0r
Entry Date(s):: Date Created: 20230518 Date Completed: 20230522 Latest Revision: 20230607
Update Code:: 20240105
PubMed Central ID:: PMC10195790
DOI:: 10.1038/s42003-023-04912-0
PMID:: 37202508
: Czasopismo naukowe

Pełny tekst

Correlated variability in neuronal activity (spike count correlations, r SC ) can constrain how information is read out from populations of neurons. Traditionally, r SC is reported as a single value summarizing a brain area. However, single values, like summary statistics, stand to obscure underlying features of the constituent elements. We predict that in brain areas containing distinct neuronal subpopulations, different subpopulations will exhibit distinct levels of r SC that are not captured by the population r SC . We tested this idea in macaque superior colliculus (SC), a structure containing several functional classes (i.e., subpopulations) of neurons. We found that during saccade tasks, different functional classes exhibited differing degrees of r SC . "Delay class" neurons displayed the highest r SC , especially during saccades that relied on working memory. Such dependence of r SC on functional class and cognitive demand underscores the importance of taking functional subpopulations into account when attempting to model or infer population coding principles.
(© 2023. This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.)

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