Semisynthetic cephalosporins. Synthesis and structure-activity relationships of 7-mandelamido-3-cephem-4-carboxylic acids.

Tytuł:: Semisynthetic cephalosporins. Synthesis and structure-activity relationships of 7-mandelamido-3-cephem-4-carboxylic acids.
Autorzy:: Hoover JR
Dunn GL
Jakas DR
Lam LL
Taggart JJ
Guarini JR
Phillips L
Źródło:: Journal of medicinal chemistry [J Med Chem] 1974 Jan; Vol. 17 (1), pp. 34-41.
Typ publikacji:: Journal Article
Język:: English
Imprint Name(s):: Publication: Washington Dc : American Chemical Society
Original Publication: [Easton, Pa.] : American Chemical Society, [c1963-
MeSH Terms:: Cephalosporins/*chemical synthesis
Mandelic Acids/*chemical synthesis
Amides/blood ; Amides/chemical synthesis ; Amides/pharmacology ; Amides/therapeutic use ; Animals ; Bacteria/drug effects ; Cephalosporins/blood ; Cephalosporins/pharmacology ; Cephalosporins/therapeutic use ; Dogs ; Escherichia coli Infections/drug therapy ; Klebsiella Infections/drug therapy ; Magnetic Resonance Spectroscopy ; Mandelic Acids/blood ; Mandelic Acids/pharmacology ; Mandelic Acids/therapeutic use ; Mice ; Microbial Sensitivity Tests ; Rabbits ; Staphylococcal Infections/drug therapy ; Stereoisomerism ; Structure-Activity Relationship
Substance Nomenclature:: 0 (Amides)
0 (Cephalosporins)
0 (Mandelic Acids)
Entry Date(s):: Date Created: 19740101 Date Completed: 19740130 Latest Revision: 20190709
Update Code:: 20240104
DOI:: 10.1021/jm00247a008
PMID:: 4585974
: Czasopismo naukowe

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