Workshop studies with monoclonal antibodies identifying a novel porcine differentiation antigen, SWC9.

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Tytuł:: Workshop studies with monoclonal antibodies identifying a novel porcine differentiation antigen, SWC9.
Autorzy:: Dominguez J; Centro de Investigación en Sanidad Animal INIA, Madrid, Spain.
Ezquerra A
Alonso F
Bullido R
McCullough K
Summerfield A
Bianchi A
Zwart RJ
Kim YB
Blecha F
Eicher S
Murtaugh MP
Pampusch M
Burger K
Źródło:: Veterinary immunology and immunopathology [Vet Immunol Immunopathol] 1998 Jan 30; Vol. 60 (3-4), pp. 343-9.
Typ publikacji:: Journal Article
Język:: English
Imprint Name(s):: Original Publication: [Amsterdam] Elsevier Scientific.
MeSH Terms:: Antibodies, Monoclonal/*metabolism
Antigens, Differentiation, Myelomonocytic/*analysis
Swine/*immunology
Animals ; Kinetics ; Macrophages/immunology ; Macrophages, Alveolar/immunology ; Monocytes/immunology ; Precipitin Tests ; Swine, Miniature ; T-Lymphocyte Subsets/immunology
Substance Nomenclature:: 0 (Antibodies, Monoclonal)
0 (Antigens, Differentiation, Myelomonocytic)
Entry Date(s):: Date Created: 19980520 Date Completed: 19980716 Latest Revision: 20190831
Update Code:: 20240104
DOI:: 10.1016/s0165-2427(97)00110-4
PMID:: 9589572
: Czasopismo naukowe

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Two monoclonal antibodies (mAb) within cluster M4 of the myeloid section of the Second International Swine CD Workshop, C4 (No. 144) and PM18-7 (No. 192), showed reactivity with thymocytes and among cells of myelomonocytic origin with mature macrophages but not with monocytes and granulocytes. Both mAb recognize a protein showing two bands of 205 kDa and 130 kDa under both reducing and non-reducing conditions. Although epitope mapping with these mAb could not be performed, this cluster received the SWC9 designation.

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