Various β-hydroxy-substituted amidines were obtained starting from methyl serinates, aldehydes or ketones, and tosyl azide. These were converted via Mitsunobu intramolecular cyclization into enantiomerically pure methyl 2-alkyl-1-tosyl-4,5-dihydro- 1H-imidazole-4-carboxylates. [ABSTRACT FROM AUTHOR]
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