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Tytuł pozycji:

Serum serotonin concentration in lean and obese dogs with myxomatous mitral valve disease.

Tytuł:
Serum serotonin concentration in lean and obese dogs with myxomatous mitral valve disease.
Autorzy:
Kyu-Tae Kim
Hee-Myung Park
Changbaig Hyun
Kyoung-Won Seo
Kun-Ho Song
Temat:
MITRAL valve diseases
SEROTONIN
BLOOD serum analysis
OBESITY in animals
ABNORMALITIES in dogs
Źródło:
Korean Journal of Veterinary Research; 2016, Vol. 56 Issue 4, p205-208, 4p
Czasopismo naukowe
The aim of the present study is to investigate the potential influence of obesity as a factor in 5- hydroxytryptamine (5-HT) concentration in myxomatous mitral valve disease (MMVD) dogs. Fifty-five client-owned dogs were enrolled in a randomized trial. Dogs were classified by echocardiography into healthy (control), mild, and moderate to severe MMVD groups. Each group was subclassified by using a 9-point body condition score (BCS); lean (BCS 5-6/9) and obese groups (BCS 7.5-9/9). Dogs with moderate to severe MMVD had lower serotonin (5- HT) concentrations than the control group (p = 0.03). Dogs with moderate to severe MMVD (p = 0.017) had lower serum 5-HT concentrations than the control group in the obese group (BCS 7.5-9/9). Significant difference was found between the lean and obese groups (p = 0.015) which are not consider severe in the MMVD group. These results suggested that 5-HT concentration was decreased with the increasing severity of MMVD, and obesity might be taken into consideration when interpreting the serotonin concentration in MMVD dogs. [ABSTRACT FROM AUTHOR]
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