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Title of the item:

The Value of Arterial Blood Gas Parameters for Prediction of Mortality in Survivors of Out-of-hospital Cardiac Arrest.

Title :
The Value of Arterial Blood Gas Parameters for Prediction of Mortality in Survivors of Out-of-hospital Cardiac Arrest.
Authors :
von Auenmueller, Katharina Isabel
Christ, Martin
Sasko, Benjamin Michel
Trappe, Hans-Joachim
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Subject Terms :
CARDIAC arrest
BLOOD gases
STANDARD deviations
RESUSCITATION
LACTATES
Source :
Journal of Emergencies, Trauma & Shock; Jul-Sep2017, Vol. 10 Issue 3, p134-139, 6p
Academic Journal
Context: Sudden cardiac death is one of the leading causes of death in Europe, and early prognostication remains challenging. There is a lack of valid parameters for the prediction of survival after cardiac arrest. Aims: This study aims to investigate if arterial blood gas parameters correlate with mortality of patients after out-of-hospital cardiac arrest. Materials and Methods: All patients who were admitted to our hospital after resuscitation following out-of-hospital cardiac arrest between January 1, 2008, and December 31, 2013, were included in this retrospective study. The patient's survival 5 days after resuscitation defined the study end-point. For the statistical analysis, the mean, standard deviation, Student's t-test, Chi-square test, and logistic regression analyses were used (level of significance P < 0.05). Results: Arterial blood gas samples were taken from 170 patients. In particular, pH <7.0 (odds ratio [OR]: 7.20; 95% confidence interval [CI]: 3.11-16.69; P < 0.001) and lactate = 5.0 mmol/L (OR: 6.79; 95% CI: 2.77-16.66; P < 0.001) showed strong and independent correlations with mortality within the first 5 days after hospital admission. Conclusion: Our study results indicate that several arterial blood gas parameters correlate with mortality of patients after out-of-hospital resuscitation. The most relevant parameters are pH and lactate because they are strongly and independently associated with mortality within the first 5 days after resuscitation. Despite this correlation, none of these parameters by oneself is strong enough to allow an early prognostication. Still, these parameters can contribute as part of a multimodal approach to assessing the patients' prognosis. [ABSTRACT FROM AUTHOR]
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