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Tytuł pozycji:

An Analysis of Perioperative Anesthetic Adverse Events in Thailand [PAAd Thai]: Allergic Reaction/Anaphylactoid/Anaphylaxis.

Tytuł :
An Analysis of Perioperative Anesthetic Adverse Events in Thailand [PAAd Thai]: Allergic Reaction/Anaphylactoid/Anaphylaxis.
Autorzy :
Pulnitiporn, Aksorn
Limapichat, Ratchayakorn
Vimuktanandana, Anantachote
Pravitharangul, Thanist
Lapisatepun, Worawut
Chernsirikasem, Nopadon
Sriraj, Wimonrat
Morakul, Sunthiti
Ariyanuchitkul, Thidarat
Pokaż więcej
Temat :
ANESTHETICS
ANAPHYLAXIS
ALLERGIES
BLOOD products
SERODIAGNOSIS
Źródło :
Journal of the Medical Association of Thailand; Nov2018, Vol. 101 Issue 11, p1509-1515, 7p
Czasopismo naukowe
Background: Perioperative anaphylaxis or anaphylactoid reaction is an uncommon event and difficult to diagnose. Clinical symptoms range from mild with skin lesion to serious life-threatening conditions. Objective: To describe characteristics of patients who developed anaphylaxis or anaphylactoid reaction during anesthesia including signs, symptoms, treatment, outcome, and suggestive strategies for perioperative anaphylaxis or anaphylactoid reaction in Thailand. Materials and Methods: A prospective descriptive study was conducted by using data from first 2,000 incident reports of the Perioperative and Anesthetic Adverse Events in Thailand [PAAd Thai] study. Patient characteristic and detail of anaphylaxis including signs, symptoms, probable causes, treatment, and immediate outcome were recorded. All data were reviewed by three experienced anesthesiologists. Descriptive statistics was used. Results: After reviewed, 70 incidents were identified as perioperative anaphylaxis or anaphylactoid reaction. Anaphylaxis occurred more commonly in female. Most (98.5%) were ASA I-III with mean age 42.6±2.5 years. Seventy-two-point-nine percent of events occurred during general anesthesia. By using clinical severity, patients were classified as grade I, II, III, in 38, 4, and 28 patients, respectively. Suspected causes were identified in 41 cases. The most common causes were antibiotic, blood component, and colloid, in 13, 9, and 6 cases, respectively. Clinical manifestations of grade III were hypotension, rash or urticarial, bronchospasm, tachycardia, and angioedema, in 21, 18, 15, 11, and 5 patients, respectively. Only 19 from 28 patients in grade III received adrenaline treatment. All patients in grade I and II recovered completely. In grade III, surgery was postponed in five cases and two cases were admitted to ICU. Only one patient received serologic test and skin test. Conclusion: To improve outcome, guidelines for perioperative anaphylaxis management should be followed. After anaphylaxis event, proper investigation to identify definite cause should be done at proper time. [ABSTRACT FROM AUTHOR]
Copyright of Journal of the Medical Association of Thailand is the property of Medical Association of Thailand and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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