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Title of the item:

Pyrrolopyrrole aza-BODIPY near-infrared photosensitizer for dual-mode imaging-guided photothermal cancer therapy.

Title:
Pyrrolopyrrole aza-BODIPY near-infrared photosensitizer for dual-mode imaging-guided photothermal cancer therapy.
Authors:
Wu, Chaolong
Huang, Xiaoyu
Tang, Yunyun
Xiao, Wanyue
Sun, Liguo
Shao, Jinjun
Dong, Xiaochen
Subject Terms:
PHOTOSENSITIZERS
ACOUSTIC imaging
CANCER treatment
Source:
Chemical Communications; 1/18/2019, Vol. 55 Issue 6, p790-793, 4p
Academic Journal
A NIR photosensitizer pyrrolopyrrole aza-BODIPY (PPAB) was synthesized in a straightforward manner. Through the use of PPAB NPs as a photothermal agent, photoacoustic imaging (PAI) and NIR fluorescence imaging (NIR-FI) can be achieved in vivo. In addition, the photothermal ablation of tumor cells can be realized both in vitro and in vivo, even at a low concentration (0.5 mg kg−1). [ABSTRACT FROM AUTHOR]
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