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Tytuł pozycji:

Efficacy and safety of Ex-PRESS® mini shunt surgery versus trabeculectomy for neovascular glaucoma: a retrospective comparative study.

Tytuł :
Efficacy and safety of Ex-PRESS® mini shunt surgery versus trabeculectomy for neovascular glaucoma: a retrospective comparative study.
Autorzy :
Kawabata, Kazuyuki
Shobayashi, Kohei
Iwao, Keiichiro
Takahashi, Eri
Tanihara, Hidenobu
Inoue, Toshihiro
Pokaż więcej
Temat :
GLAUCOMA surgery
TRABECULECTOMY
SURGICAL anastomosis
COMPARATIVE studies
GLAUCOMA
INTRAOCULAR pressure
RESEARCH methodology
MEDICAL cooperation
RESEARCH
RESEARCH funding
SURGICAL complications
EVALUATION research
PROPORTIONAL hazards models
RETROSPECTIVE studies
KAPLAN-Meier estimator
Źródło :
BMC Ophthalmology; 3/12/2019, Vol. 19 Issue 1, pN.PAG-N.PAG, 1p
Czasopismo naukowe
Background: The objective of this study is to evaluate and compare the short-term efficacy and safety of Ex-PRESS® mini shunt surgery and trabeculectomy for neovascular glaucoma (NVG).Methods: Patients with NVG who underwent Ex-PRESS® mini shunt surgery or trabeculectomy as a primary glaucoma surgery between March 2013 and October 2015 were included in the study, and their medical charts were retrospectively reviewed. The Ex-PRESS® and trabeculectomy groups included 14 eyes and 30 eyes, respectively. Surgical failure was defined by an intraocular pressure (IOP) of ≥21 mmHg (condition A) or ≥ 18 mmHg (condition B); Kaplan-Meier survival analyses and the multivariable Cox proportional hazards model were used to assess efficacies.Results: Kaplan-Meier survival analyses indicated that the probabilities of success at 1 year for the Ex-PRESS® group were 25.7 and 31.8% based on complete and qualified success under condition A, respectively. The corresponding values for the trabeculectomy group were 47.8 and 69.3%, and there was a significant difference in qualified success with condition A (Fig. 1; P = 0.018), while there were no significant differences in the other criteria. Ex-PRESS® mini shunt surgery and higher intraocular pressure were independent prognostic factors using Cox proportional hazards model analyses in qualified success as in condition A (P = 0.012 and 0.0495, respectively). The occurrences of postsurgical hyphema and bleb leaks were significantly higher in the trabeculectomy group (P = 0.005 and 0.008, respectively).Conclusion: During a 1 year follow-up, Ex-PRESS® mini shunt surgery was a less effective, but safer treatment for NVG compared with trabeculectomy. [ABSTRACT FROM AUTHOR]
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