Charakteristika aterosklerotického plátu a riziko mozkové ischemie při stentování vnitřní karotidy. - OpacWWW

Tytuł:: Charakteristika aterosklerotického plátu a riziko mozkové ischemie při stentování vnitřní karotidy.
Autorzy:: Charvát, F.
Vrána, J.
Netuka, D.
Cihlář, F.
Krajina, A.
Chovanec, V.
Herzig, R.
Procházka, V.
Roubec, M.
Kešnerová, P.
Školoudík, D.
Temat:: ATHEROSCLEROTIC plaque
CEREBRAL ischemia
INTERNAL carotid artery
BRAIN damage
ANGIOPLASTY
Alternatywny tytuł:: Atherosclerotic plaque characteristics and the risk of brain ischemia dur--ing internal carotid artery stent--ing. (English)
Źródło:: Česká a Slovenská Neurologie a Neurochirurgie; 2020, Vol. 83 Issue 1, p84-94, 11p
Abstract (English):: Aim: The aim of a prospective multicenter study was to determine whether the risk of develop--ing a new ischemic brain lesion on control MRI is dependent on some of the characteristics of atherosclerotic plaque detected by duplex sonography, MRI and CTA. Materials and methods: Patients with internal carotid artery stenosis (70– 95%) indicated for carotid angioplasty and stent--ing (CAS) were consecutively included in the prospective observational study. All enrol-led patients underwent neurological and physical examinations, duplex sonographic examination of the carotid arteries with evaluation of the structure of atherosclerotic plaque in the ultrasound B-mode, CTA of the cervical and cerebral arteries and MRI of the neck and brain. The univariate and multivariate logistic regres-sion analyses were performed to identify factors af-fect--ing the risk of the onset of brain ischemia following CAS. Results: A total of 121 patients (93 males, age 70.5 ± 7.6 years) were enrol-led in the study. Within 30 days of the CAS, 4 patients suf-fered from stroke, 1 patient suf-fered from a transient ischemic attack and 1 patient died. A new ischemic lesion on control brain MRI was detected in 34 (28.1%) patients. Us--ing univariate and multivariate logistic regres-sion analysis, no predictor (atherosclerotic plaque characteristics, history data, CAS data) was found to influence the risk of the onset of new brain ischemia. Conclusion: Characteristics of atherosclerotic plaque in the area of the internal carotid artery stenosis does not af-fect the risk of develop--ing brain ischemia detected by brain MRI following CAS. [ABSTRACT FROM AUTHOR]
: Czasopismo naukowe

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Charakteristika aterosklerotického plátu a riziko mozkové ischemie při stentování vnitřní karotidy.