Green synthesis approach for Fe (III), Cu (II), Zn (II) and Ni (II)‐Schiff base complexes, spectral, conformational, MOE‐docking and biological studies.
Al‐Hazmi, Gamil A.A.
Abou‐Melha, Khlood S.
El‐Metwaly, Nashwa M.
Applied Organometallic Chemistry; Mar2020, Vol. 34 Issue 3, pN.PAG-N.PAG, 1p
Green synthesis of Fe (III), Cu (II), Zn (II) and Ni (II)‐Schiff's‐base complexes from 2‐oxo‐N‐(pyridine‐2‐yl)‐2‐(2‐(1‐(pyridin‐2‐yl)ethylidene)hydrazinyl)acetamide(H2L)ligand. All new complexes were characterized via several spectroscopic and analytical techniques, to establish their molecular and structural formulae. All complexes appeared have 1:1 molar ratio (M:L). The ligand contributed as a neutral poly‐dentate towards the metal ions. Moreover, material‐studio program was used to predict the most fitted atomic‐skeletons for investigated compounds by applying DFT method. MOE docking module (vs. 2015) was used to examine the degree of inhibition for new compounds versus three infected‐cell proteins (1bqb, 2gt1 and 4esw). Also, antimicrobial and colorimetric assess for compounds that bind DNA were performed [ABSTRACT FROM AUTHOR]
Copyright of Applied Organometallic Chemistry is the property of John Wiley & Sons, Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Zaloguj się, aby uzyskać dostęp do pełnego tekstu.